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6R90
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BU of 6r90 by Molmil
Cryo-EM structure of NCP-THF2(+1)-UV-DDB class A
分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ...
著者Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-04-02
公開日2019-06-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
6R91
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BU of 6r91 by Molmil
Cryo-EM structure of NCP_THF2(-3)-UV-DDB
分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ...
著者Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-04-02
公開日2019-06-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
6R8Z
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BU of 6r8z by Molmil
Cryo-EM structure of NCP_THF2(-1)-UV-DDB
分子名称: DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ...
著者Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-04-02
公開日2019-06-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
2ZKD
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BU of 2zkd by Molmil
Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*DCP*DTP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DTP*DGP*DC)-3'), ...
著者Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M.
登録日2008-03-19
公開日2008-09-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
Nature, 455, 2008
6R92
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BU of 6r92 by Molmil
Cryo-EM structure of NCP-THF2(+1)-UV-DDB class B
分子名称: DNA damage-binding protein 1,DNA damage-binding protein 1, DNA damage-binding protein 2, Histone H2A type 1-B/E, ...
著者Matsumoto, S, Cavadini, S, Bunker, R.D, Thoma, N.H.
登録日2019-04-02
公開日2019-06-12
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献DNA damage detection in nucleosomes involves DNA register shifting.
Nature, 571, 2019
7K01
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BU of 7k01 by Molmil
Structure of TFIIH in TFIIH/Rad4-Rad23-Rad33 DNA opening complex
分子名称: DNA repair helicase RAD25, DNA repair helicase RAD3, General transcription and DNA repair factor IIH subunit SSL1, ...
著者van Eeuwen, T, Min, J.H, Murakami, K.
登録日2020-09-02
公開日2021-07-28
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structure of TFIIH/Rad4-Rad23-Rad33 in damaged DNA opening in nucleotide excision repair.
Nat Commun, 12, 2021
8EWV
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BU of 8ewv by Molmil
DNA-encoded library (DEL)-enabled discovery of proximity inducing small molecules
分子名称: Bromodomain-containing protein 4, Elongin-B, Elongin-C, ...
著者Schreiber, S.L, Shu, W, Ma, X, Michaud, G, Bonazzi, S, Berst, F.
登録日2022-10-24
公開日2023-10-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献DNA-encoded library-enabled discovery of proximity-inducing small molecules.
Nat.Chem.Biol., 20, 2024
6WGG
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BU of 6wgg by Molmil
Atomic model of pre-insertion mutant OCCM-DNA complex(ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
分子名称: Cell division control protein 6, Cell division cycle protein CDT1, DNA (41-MER), ...
著者Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
登録日2020-04-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGC
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BU of 6wgc by Molmil
Atomic model of semi-attached mutant OCCM-DNA complex (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation)
分子名称: Cell division control protein 6, DNA (41-MER), DNA replication licensing factor MCM3, ...
著者Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
登録日2020-04-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WGI
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BU of 6wgi by Molmil
Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution
分子名称: Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ...
著者Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
登録日2020-04-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
4CI3
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BU of 4ci3 by Molmil
Structure of the DDB1-CRBN E3 ubiquitin ligase bound to Pomalidomide
分子名称: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Pomalidomide, ...
著者Fischer, E.S, Boehm, K, Thoma, N.H.
登録日2013-12-05
公開日2014-07-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Nature, 512, 2014
4CI2
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BU of 4ci2 by Molmil
Structure of the DDB1-CRBN E3 ubiquitin ligase bound to lenalidomide
分子名称: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Lenalidomide, ...
著者Fischer, E.S, Boehm, K, Thoma, N.H.
登録日2013-12-05
公開日2014-07-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Nature, 512, 2014
4CI1
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BU of 4ci1 by Molmil
Structure of the DDB1-CRBN E3 ubiquitin ligase bound to thalidomide
分子名称: DNA DAMAGE-BINDING PROTEIN 1, PROTEIN CEREBLON, S-Thalidomide, ...
著者Fischer, E.S, Boehm, K, Thoma, N.H.
登録日2013-12-05
公開日2014-07-16
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structure of the Ddb1-Crbn E3 Ubiquitin Ligase in Complex with Thalidomide.
Nature, 512, 2014
3RCZ
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BU of 3rcz by Molmil
Rad60 SLD2 Ubc9 Complex
分子名称: DNA repair protein rad60, SUMO-conjugating enzyme ubc9
著者Perry, J.J.P, Arvai, A.S, Tainer, J.A.
登録日2011-03-31
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes.
Mol.Cell.Biol., 31, 2011
5NP7
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BU of 5np7 by Molmil
CryoEM structure of Human Rad51 on single-stranded DNA to 4.2A resolution.
分子名称: DNA repair protein RAD51 homolog 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Short, J.M, Venkitaraman, A.
登録日2017-04-13
公開日2017-05-03
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献High-resolution structure of the presynaptic RAD51 filament on single-stranded DNA by electron cryo-microscopy.
Nucleic Acids Res., 44, 2016
5CKK
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BU of 5ckk by Molmil
Crystal structure of 9DB1* deoxyribozyme
分子名称: DNA (44-MER), MAGNESIUM ION, RNA (5'-R(P*GP*CP*AP*CP*UP*AP*GP*AP*UP*CP*GP*GP*AP*UP*G)-3')
著者Ponce-Salvatierra, A, Hoebartner, C, Pena, V.
登録日2015-07-15
公開日2016-01-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.801 Å)
主引用文献Crystal structure of a DNA catalyst.
Nature, 529, 2016
6OEM
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BU of 6oem by Molmil
Cryo-EM structure of mouse RAG1/2 PRC complex (DNA0)
分子名称: DNA (46-MER), DNA (57-MER), High mobility group protein B1, ...
著者Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M.
登録日2019-03-27
公開日2020-01-29
最終更新日2020-02-26
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cutting antiparallel DNA strands in a single active site.
Nat.Struct.Mol.Biol., 27, 2020
3SR2
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BU of 3sr2 by Molmil
Crystal Structure of Human XLF-XRCC4 Complex
分子名称: DNA repair protein XRCC4, Non-homologous end-joining factor 1
著者Hammel, M, Classen, S, Tainer, J.A.
登録日2011-07-06
公開日2011-07-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.9708 Å)
主引用文献XRCC4 Protein Interactions with XRCC4-like Factor (XLF) Create an Extended Grooved Scaffold for DNA Ligation and Double Strand Break Repair.
J.Biol.Chem., 286, 2011
4M6F
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BU of 4m6f by Molmil
Dimer of the G-Segment Invertase bound to a DNA substrate
分子名称: DNA-invertase, gix site analog
著者Ritacco, C.J, Wang, J, Steitz, T.A.
登録日2013-08-09
公開日2014-03-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (4.99 Å)
主引用文献Exploiting large non-isomorphous differences for phase determination of a G-segment invertase-DNA complex.
Acta Crystallogr.,Sect.D, 70, 2014
6M2V
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BU of 6m2v by Molmil
Crystal structure of UHRF1 SRA complexed with fully-mCHG DNA.
分子名称: DNA (5'-D(*TP*CP*AP*CP*GP*(5CM)P*TP*GP*CP*GP*TP*GP*A)-3'), E3 ubiquitin-protein ligase UHRF1
著者Abhishek, S, Nakarakanti, N.K, Deeksha, W, Rajakumara, E.
登録日2020-03-01
公開日2021-01-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA.
Int.J.Biol.Macromol., 170, 2021
2D8M
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BU of 2d8m by Molmil
Solution structure of the first BRCT domain of DNA-repair protein XRCC1
分子名称: DNA-repair protein XRCC1
著者Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-06
公開日2006-06-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the first BRCT domain of DNA-repair protein XRCC1
To be published
3SZQ
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BU of 3szq by Molmil
Structure of an S. pombe APTX/DNA/AMP/Zn complex
分子名称: 5'-D(*CP*CP*CP*TP*G)-3', 5'-D(*TP*AP*TP*CP*GP*GP*AP*AP*TP*CP*AP*GP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ...
著者Tumbale, P, Krahn, J, Williams, R.S.
登録日2011-07-19
公開日2011-10-12
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.353 Å)
主引用文献Structure of an aprataxin-DNA complex with insights into AOA1 neurodegenerative disease.
Nat.Struct.Mol.Biol., 18, 2011
3Q4F
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BU of 3q4f by Molmil
Crystal structure of xrcc4/xlf-cernunnos complex
分子名称: DNA repair protein XRCC4, Non-homologous end-joining factor 1
著者Ropars, V, Legrand, P, Charbonnier, J.B.
登録日2010-12-23
公開日2011-08-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (5.5 Å)
主引用文献Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Proc.Natl.Acad.Sci.USA, 108, 2011
6WJG
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BU of 6wjg by Molmil
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
分子名称: DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S.
登録日2020-04-13
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020
6WJF
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BU of 6wjf by Molmil
PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma
分子名称: DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S.
登録日2020-04-13
公開日2020-12-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma.
Plos Biol., 18, 2020

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