1FNI
 
 | | CRYSTAL STRUCTURE OF PORCINE BETA TRYPSIN WITH 0.01% POLYDOCANOL | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, SULFATE ION, ... | | 著者 | Deepthi, S, Johnson, A, Pattabhi, V. | | 登録日 | 2000-08-22 | | 公開日 | 2000-09-13 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structures of porcine beta-trypsin-detergent complexes: the stabilization of proteins through hydrophilic binding of polydocanol.
Acta Crystallogr.,Sect.D, 57, 2001
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6B2C
 | | Macrophage Migration Inhibitory Factor in Complex with a Naphthyridinone Inhibitor (4b) | | 分子名称: | Macrophage migration inhibitory factor, SULFATE ION, {2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]-8-oxo-1,7-naphthyridin-7(8H)-yl}acetic acid | | 著者 | Krimmer, S.G, Robertson, M.J, Jorgensen, W.L. | | 登録日 | 2017-09-19 | | 公開日 | 2018-01-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Adding a Hydrogen Bond May Not Help: Naphthyridinone vs Quinoline Inhibitors of Macrophage Migration Inhibitory Factor.
ACS Med Chem Lett, 8, 2017
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1FI0
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5IYV
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7JLL
 | | The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site | | 分子名称: | 1,2-ETHANEDIOL, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, CESIUM ION, ... | | 著者 | Hilario, E, Dunn, M.F, Mueller, L.J. | | 登録日 | 2020-07-29 | | 公開日 | 2021-08-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | The internal aldimine crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-S377A in complex with inhibitor 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site and L-Tryptophan at the enzyme beta-site.
To be Published
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8UXB
 | | E. coli 70S ribosome with unmodified P/E-tRNAPro(GGG) bound to slippery P-site CCC-C codon | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Kimbrough, E.M, Dunham, C.M, Nguyen, H.A. | | 登録日 | 2023-11-09 | | 公開日 | 2025-07-09 | | 最終更新日 | 2025-08-27 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting.
Nat Commun, 16, 2025
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3H6D
 | | Structure of the mycobacterium tuberculosis DUTPase D28N mutant | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ... | | 著者 | Leveles, I, Harmat, V, Nagy, G, Takacs, E, Lopata, A, Toth, J, Vertessy, B.G. | | 登録日 | 2009-04-23 | | 公開日 | 2009-11-24 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Direct contacts between conserved motifs of different subunits provide major contribution to active site organization in human and mycobacterial dUTPases.
Febs Lett., 584, 2010
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8UZG
 | | E. coli 70S ribosome with unmodified e*/E-tRNAPro(GGG) bound to slippery P-site CCC-C codon | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Kimbrough, E.M, Dunham, C.M, Nguyen, H.A. | | 登録日 | 2023-11-15 | | 公開日 | 2025-07-09 | | 最終更新日 | 2025-08-27 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting.
Nat Commun, 16, 2025
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4M97
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8V03
 | | E. coli 70S ribosome with unmodified P/E-tRNAPro(GGG) bound to slippery P-site CCC-C codon | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S11, ... | | 著者 | Kimbrough, E.M, Dunham, C.M, Nguyen, H.A. | | 登録日 | 2023-11-16 | | 公開日 | 2025-07-09 | | 最終更新日 | 2025-08-27 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | An RNA modification prevents extended codon-anticodon interactions from facilitating +1 frameshifting.
Nat Commun, 16, 2025
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5OLE
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6B4V
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1MD4
 | | A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to valine | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase | | 著者 | Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W. | | 登録日 | 2002-08-06 | | 公開日 | 2002-08-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1
J.Biol.Chem., 278, 2003
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5UP4
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5A5S
 | | NN-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 5-5-methoxypyridin-3-yl-3- methyl-8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one | | 分子名称: | 1,2-ETHANEDIOL, 5-(5-methoxypyridin-3-yl)-3-methyl-8-[(piperidin-4-yl)amino]-1,2-dihydro-1,7-naphthyridin-2-one, BROMODOMAIN-CONTAINING PROTEIN 4 | | 著者 | Chung, C, Bamborough, P, Demont, E. | | 登録日 | 2015-06-20 | | 公開日 | 2015-07-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Fragment-Based Discovery of Low-Micromolar Atad2 Bromodomain Inhibitors.
J.Med.Chem., 58, 2015
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6AQO
 | | Crystal structure of hypoxanthine-guanine-xanthine phosphorybosyltranferase in complex with {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid) | | 分子名称: | Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, {[(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)propane-1,2-diyl]bis(oxyethane-2,1-diyl)}bis(phosphonic acid) | | 著者 | Teran, D, Gudday, L.W. | | 登録日 | 2017-08-21 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Evaluation of the Trypanosoma brucei 6-oxopurine salvage pathway as a potential target for drug discovery.
PLoS Negl Trop Dis, 12, 2018
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7VN6
 | | Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning CGCACGTGCG | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*CP*GP*CP*AP*CP*GP*TP*GP*CP*GP*AP*AP*A)-3'), Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ... | | 著者 | Nosaki, S, Tanokura, M, Miyakawa, T. | | 登録日 | 2021-10-10 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Brassinosteroid-induced gene repression requires specific and tight promoter binding of BIL1/BZR1 via DNA shape readout.
Nat.Plants, 8, 2022
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3L6P
 | | Crystal Structure of Dengue Virus 1 NS2B/NS3 protease | | 分子名称: | CADMIUM ION, NICKEL (II) ION, SULFATE ION, ... | | 著者 | Chandramouli, S, Joseph, J.S, Daudenarde, S, Gatchalian, J, Cornillez-Ty, C, Kuhn, P. | | 登録日 | 2009-12-23 | | 公開日 | 2010-03-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Serotype-specific structural differences in the protease-cofactor complexes of the dengue virus family.
J.Virol., 84, 2010
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7VN3
 | | Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning CACACGTGTG | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*CP*AP*CP*AP*CP*GP*TP*GP*TP*GP*AP*AP*A)-3'), Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ... | | 著者 | Nosaki, S, Tanokura, M, Miyakawa, T. | | 登録日 | 2021-10-10 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Brassinosteroid-induced gene repression requires specific and tight promoter binding of BIL1/BZR1 via DNA shape readout.
Nat.Plants, 8, 2022
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7VN4
 | | Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning TCCACGTGGA | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*TP*CP*CP*AP*CP*GP*TP*GP*AP*AP*AP*AP*A)-3'), Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ... | | 著者 | Nosaki, S, Tanokura, M, Miyakawa, T. | | 登録日 | 2021-10-10 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Brassinosteroid-induced gene repression requires specific and tight promoter binding of BIL1/BZR1 via DNA shape readout.
Nat.Plants, 8, 2022
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4ALF
 | | Pseudomonas fluorescens PhoX in complex with phosphate | | 分子名称: | 1,2-ETHANEDIOL, ALKALINE PHOSPHATASE PHOX, CALCIUM ION, ... | | 著者 | Yong, S.C, Roversi, P, Lillington, J.E.D, Zeldin, O.B, Garman, E.F, Lea, S.M, Berks, B.C. | | 登録日 | 2012-03-02 | | 公開日 | 2013-03-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | A Complex Iron-Calcium Cofactor Catalyzing Phosphotransfer Chemistry
Science, 345, 2014
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5OQ2
 | | Se-SAD structure of the functional region of Cwp19 from Clostridium difficile | | 分子名称: | 1,2-ETHANEDIOL, Cwp19, PHOSPHATE ION | | 著者 | Bradshaw, W.J, Kirby, J.M, Roberts, A.K, Shone, C.C, Acharya, K.R. | | 登録日 | 2017-08-10 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile.
FEBS J., 284, 2017
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7VN5
 | | Crystal structure of MBP-fused BIL1/BZR1 (21-90) in complex with double-stranded DNA contaning TTCACGTGAA | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*TP*TP*TP*TP*CP*AP*CP*GP*TP*GP*AP*AP*AP*AP*A)-3'), Maltodextrin-binding protein,Protein BRASSINAZOLE-RESISTANT 1, ... | | 著者 | Nosaki, S, Tanokura, M, Miyakawa, T. | | 登録日 | 2021-10-10 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Brassinosteroid-induced gene repression requires specific and tight promoter binding of BIL1/BZR1 via DNA shape readout.
Nat.Plants, 8, 2022
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3C8U
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3SIL
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