PDB: 184050 件ウェブページステータス検索Chemie searchBIRD

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5SYG	Cryo-EM reconstruction of zampanolide-bound microtubule 分子名称: (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Kellogg, E.H, Hejab, N.M.A, Nogales, E. 登録日 2016-08-11 公開日 2017-02-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429, 2017
2QST	Crystal structure of the V39C mutant of the N-terminal domain of carcinoembryonic antigen (CEA) 分子名称: Carcinoembryonic antigen-related cell adhesion molecule 5 著者 Le Trong, I, Korotkova, N, Moseley, S.L, Stenkamp, R.E. 登録日 2007-07-31 公開日 2008-01-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation. Mol.Microbiol., 67, 2008
4E2F	Crystal Structure of E. coli Aspartate Transcarbamoylase K164E/E239K Mutant in an intermediate state 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION 著者 Guo, W, Kantrowitz, E.R. 登録日 2012-03-08 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase. Proc.Natl.Acad.Sci.USA, 109, 2012
6SWC	IC2B model of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi 分子名称: 16S ribosomal rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Coureux, P.-D, Mechulam, Y, Schmitt, E. 登録日 2019-09-20 公開日 2020-02-19 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation. Commun Biol, 3, 2020
6SWE	IC2 head of cryo-EM structure of a full archaeal ribosomal translation initiation complex devoid of aIF1 in P. abyssi 分子名称: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S13, ... 著者 Coureux, P.-D, Mechulam, Y, Schmitt, E. 登録日 2019-09-20 公開日 2020-02-19 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM study of an archaeal 30S initiation complex gives insights into evolution of translation initiation. Commun Biol, 3, 2020
6SG4	Structure of CDK2/cyclin A M246Q, S247EN 分子名称: Cyclin-A2, Cyclin-dependent kinase 2 著者 Salamina, M, Basle, A, Massa, B, Noble, M.E.M, Endicott, J.A. 登録日 2019-08-02 公開日 2021-01-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation. J.Mol.Biol., 433, 2021
1FL3	CRYSTAL STRUCTURE OF THE BLUE FLUORESCENT ANTIBODY (19G2) IN COMPLEX WITH STILBENE HAPTEN AT 277K 分子名称: 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, BLUE FLUORESCENT ANTIBODY (19G2)-HEAVY CHAIN, BLUE FLUORESCENT ANTIBODY (19G2)-LIGHT CHAIN 著者 Stevens, R.C, Beuscher IV, A.E. 登録日 2000-08-11 公開日 2000-11-01 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Blue-fluorescent antibodies. Science, 290, 2000
5SYC	Near-atomic resolution cryo-EM reconstruction of peloruside-stabilized microtubule 分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Kellogg, E.H, Nogales, E. 登録日 2016-08-10 公開日 2017-02-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures. J. Mol. Biol., 429, 2017
1FSA	THE T-STATE STRUCTURE OF LYS 42 TO ALA MUTANT OF THE PIG KIDNEY FRUCTOSE 1,6-BISPHOSPHATASE EXPRESSED IN E. COLI 分子名称: 6-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, FRUCTOSE 1,6-BISPHOSPHATASE, ... 著者 Lu, G, Stec, B, Giroux, E, Kantrowitz, E.R. 登録日 1996-08-24 公開日 1997-09-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Evidence for an active T-state pig kidney fructose 1,6-bisphosphatase: interface residue Lys-42 is important for allosteric inhibition and AMP cooperativity. Protein Sci., 5, 1996
7BQO	The structure of HpiI in complex with its substrate analogue 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(E,2S,4S)-2,4-dimethyloct-6-enoyl]-4-oxidanyl-1H-pyridin-2-one, GLYCEROL, ... 著者 Cai, Y.J, Ohashi, M, Zhou, J.H, Tang, Y. 登録日 2020-03-25 公開日 2020-10-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 An enzymatic Alder-ene reaction. Nature, 586, 2020
1KN9	CRYSTAL STRUCTURE OF A BACTERIAL SIGNAL PEPTIDASE APO-ENZYME, IMPLICATIONS FOR SIGNAL PEPTIDE BINDING AND THE SER-LYS DYAD MECHANISM. 分子名称: Signal peptidase I 著者 Paetzel, M, Dalbey, R.E, Strynadka, N.C.J. 登録日 2001-12-18 公開日 2002-01-30 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of a bacterial signal peptidase apoenzyme: implications for signal peptide binding and the Ser-Lys dyad mechanism J.Biol.Chem., 277, 2002
4LJZ	Crystal Structure Analysis of the E.coli holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.5871 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4XB6	Structure of the E. coli C-P lyase core complex 分子名称: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ... 著者 Brodersen, D.E. 登録日 2014-12-16 公開日 2015-08-19 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural insights into the bacterial carbon-phosphorus lyase machinery. Nature, 525, 2015
1KK2	Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDP-Mg2+ 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... 著者 Schmitt, E, Blanquet, S, Mechulam, Y. 登録日 2001-12-06 公開日 2002-04-10 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J., 21, 2002
6EUD	Crystal structure of E. coli DExH-box NTPase HrpB 分子名称: 1,2-ETHANEDIOL, ATP-dependent RNA helicase HrpB 著者 Pietrzyk-Brzezinska, A.J, Wahl, M.C. 登録日 2017-10-30 公開日 2018-09-12 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the Escherichia coli DExH-Box NTPase HrpB. Structure, 26, 2018
1ZA2	Structure of wild-type E. coli Aspartate Transcarbamoylase in the presence of CTP, carbamoyl phosphate at 2.50 A resolution 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Wang, J, Stieglitz, K.A, Cardia, J.P, Kantrowitz, E.R. 登録日 2005-04-05 公開日 2005-06-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase Proc.Natl.Acad.Sci.Usa, 102, 2005
1KK1	Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDPNP-Mg2+ 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ZINC ION, ... 著者 Schmitt, E, Blanquet, S, Mechulam, Y. 登録日 2001-12-06 公開日 2002-04-10 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J., 21, 2002
4BWO	The FedF adhesin from entrrotoxigenic Escherichia coli is a sulfate- binding lectin 分子名称: BROMIDE ION, F18 FIMBRIAL ADHESIN AC, SULFATE ION 著者 Lonardi, E, Moonens, K, Buts, L, de Boer, A.R, Olsson, J.D.M, Weiss, M.S, Fabre, E, Guerardel, Y, Deelder, A.M, Oscarson, S, Wuhrer, M, Bouckaert, J. 登録日 2013-07-03 公開日 2013-08-28 最終更新日 2014-05-28 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia Coli Biology, 2, 2013
2X93	Crystal structure of AnCE-trandolaprilat complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ANGIOTENSIN CONVERTING ENZYME, ... 著者 Akif, M, Georgiadis, D, Mahajan, A, Dive, V, Sturrock, E.D, Isaac, R.E, Acharya, K.R. 登録日 2010-03-14 公開日 2010-06-02 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 High Resolution Crystal Structures of Drosophila Melanogaster Angiotensin Converting Enzyme in Complex with Novel Inhibitors and Anti- Hypertensive Drugs. J.Mol.Biol., 400, 2010
4LK0	Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex 分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9103 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
7YZP	Hairpin-bound state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and a DNA hairpin 分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA hairpin (59-MER), MAGNESIUM ION, ... 著者 Gut, F, Kaeshammer, L, Lammens, K, Bartho, J, van de Logt, E, Kessler, B, Hopfner, K.P. 登録日 2022-02-21 公開日 2022-08-17 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50. Mol.Cell, 82, 2022
1LXC	Crystal Structure of E. Coli Enoyl Reductase-NAD+ with a Bound Acrylamide Inhibitor 分子名称: 3-(6-AMINOPYRIDIN-3-YL)-N-METHYL-N-[(1-METHYL-1H-INDOL-2-YL)METHYL]ACRYLAMIDE, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Miller, W.H, Seefeld, M.A, Newlander, K.A, Uzinskas, I.N, Burgess, W.J, Heerding, D.A, Yuan, C.C.K, Head, M.S, Payne, D.J, Rittenhouse, S.F, Moore, T.D, Pearson, S.C, Dewolf, V, Berry, W.E, Keller, P.M, Polizzi, B.J, Qiu, X, Janson, C.A, Huffman, W.F. 登録日 2002-06-05 公開日 2002-09-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI). J.Med.Chem., 45, 2002
7Z04	10 mM Rb+ soak of beryllium fluoride inhibited Na+,K+-ATPase, E2-BeFx (rigid body model) 分子名称: BERYLLIUM TRIFLUORIDE ION, FXYD domain-containing ion transport regulator, MAGNESIUM ION, ... 著者 Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shasavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P. 登録日 2022-02-22 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (7.5 Å) 主引用文献 The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. J.Biol.Chem., 298, 2022
7YZR	50 mM Rb+ soak of beryllium fluoride inhibited Na+,K+-ATPase, E2-BeFx (rigid body model) 分子名称: BERYLLIUM TRIFLUORIDE ION, FXYD domain-containing ion transport regulator, MAGNESIUM ION, ... 著者 Fruergaard, M.U, Dach, I, Andersen, J.L, Ozol, M, Shasavar, A, Quistgaard, E.M, Poulsen, H, Fedosova, N.U, Nissen, P. 登録日 2022-02-21 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (6.92 Å) 主引用文献 The Na + ,K + -ATPase in complex with beryllium fluoride mimics an ATPase phosphorylated state. J.Biol.Chem., 298, 2022
1HJR	ATOMIC STRUCTURE OF THE RUVC RESOLVASE: A HOLLIDAY JUNCTION-SPECIFIC ENDONUCLEASE FROM E. COLI 分子名称: HOLLIDAY JUNCTION RESOLVASE (RUVC) 著者 Ariyoshi, M, Vassylyev, D.G, Morikawa, K. 登録日 1994-12-02 公開日 1995-02-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Atomic structure of the RuvC resolvase: a holliday junction-specific endonuclease from E. coli. Cell(Cambridge,Mass.), 78, 1994

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