7YZP

Hairpin-bound state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and a DNA hairpin

Summary for 7YZP

• Entry DOI: 10.2210/pdb7yzp/pdb
• Related: 7YZO
• EMDB information: 14391 14393
• Descriptor: DNA hairpin (59-MER), Nuclease SbcCD subunit D, Nuclease SbcCD subunit C, ... (6 entities in total)
• Functional Keywords: abc-type atpase, nuclease, dna repair, dna binding protein
• Biological source: Escherichia coli; More
• Total number of polymer chains: 5
• Total formula weight: 353251.16

Authors

Gut, F.,Kaeshammer, L.,Lammens, K.,Bartho, J.,van de Logt, E.,Kessler, B.,Hopfner, K.P. (deposition date: 2022-02-21, release date: 2022-08-17, Last modification date: 2022-09-28)

• Primary citation: Gut, F.,Kashammer, L.,Lammens, K.,Bartho, J.D.,Boggusch, A.M.,van de Logt, E.,Kessler, B.,Hopfner, K.P.; Structural mechanism of endonucleolytic processing of blocked DNA ends and hairpins by Mre11-Rad50.; Mol.Cell, 82:3513-3522.e6, 2022; PubMed: 35987200; DOI: 10.1016/j.molcel.2022.07.019

Experimental method

ELECTRON MICROSCOPY (4 Å)