7YZP
Hairpin-bound state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ADP and a DNA hairpin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | DNA hairpin (59-MER) | polymer | 75 | 23144.8 | 1 | synthetic construct | ||
| 2 | B, C (A, B) | Nuclease SbcCD subunit D | polymer | 407 | 45640.3 | 2 | UniProt (P0AG76) Pfam (PF00149) Pfam (PF12320) | Escherichia coli | |
| 3 | D, E (C, D) | Nuclease SbcCD subunit C | polymer | 1048 | 118851.5 | 2 | UniProt (P13458) Pfam (PF13476) Pfam (PF13558) | Escherichia coli | |
| 4 | F, G, H, I (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 4 | Chemie (MN) | |||
| 5 | J, L (C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 6 | K, M (C, D) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A, B: 1 - 400 (UniProt: P0AG76)
| PDB | External Database | Details |
|---|---|---|
| Gln 84 | His 84 | engineered mutation |
| Gly 401 | - | expression tag |
| His 402 | - | expression tag |
| His 403 | - | expression tag |
| His 404 | - | expression tag |
| His 405 | - | expression tag |
| His 406 | - | expression tag |
| His 407 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 352128.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1122.8 | |
| All* | Total formula weight | 353251.2 |
