PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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5ENZ	S. aureus MnaA-UDP co-structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, TETRAETHYLENE GLYCOL, ... 著者 Fischmann, T.O. 登録日 2015-11-09 公開日 2016-04-27 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Chemical Genetic Analysis and Functional Characterization of Staphylococcal Wall Teichoic Acid 2-Epimerases Reveals Unconventional Antibiotic Drug Targets. Plos Pathog., 12, 2016
2BBL	NMR structures of the peptide linked to the genome (VPg) of poliovirus in a stabilizing solvent 分子名称: Genome linked protein VPg 著者 Schein, C.H, Oezguen, N. 登録日 2005-10-17 公開日 2006-03-28 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 NMR structure of the viral peptide linked to the genome (VPg) of poliovirus. Peptides, 27, 2006
5EOS	Crystallizing Strained DNA: Self-Assembly of 3D Crystals Containing a Torsionally-Stressed Component 分子名称: DNA (5'-D(*TP*CP*TP*GP*AP*TP*GP*TP*GP*CP*TP*GP*C)-3'), DNA (5'-D(P*AP*CP*GP*GP*AP*CP*AP*TP*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*AP*CP*CP*GP*T)-3'), ... 著者 Hernandez, C, Birktoft, J.J, Seeman, N.C. 登録日 2015-11-10 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (4.7 Å) 主引用文献 Self-Assembly of 3D DNA Crystals Containing a Torsionally Stressed Component. Cell Chem Biol, 2017
4ZRZ	PlyCB mutant R66E 分子名称: PlyCB 著者 Gallagher, D.T, Nelson, D.C, Shen, Y. 登録日 2015-05-12 公開日 2016-09-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 A bacteriophage endolysin that eliminates intracellular streptococci. Elife, 5, 2016
3UR4	Crystal structure of human WD repeat domain 5 with compound 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... 著者 Dong, A, Dombrovski, L, Senisterra, G, Wernimont, A, Wasney, G.A, Allali Hassani, A, Nguyen, K.T, Smil, D, Bolshan, Y, Hajian, T, Poda, G, Chau, I, Al-Awar, R, Bountra, C, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Brown, P, Schapira, M, Vedadi, M, Wu, H, Structural Genomics Consortium (SGC) 登録日 2011-11-21 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Small-molecule inhibition of MLL activity by disruption of its interaction with WDR5. Biochem. J., 449, 2013
4ZS8	Crystal structure of ligand-free, full length DasR 分子名称: 1,2-ETHANEDIOL, HTH-type transcriptional repressor DasR 著者 Fillenberg, S.B, Muller, Y.A. 登録日 2015-05-13 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structures of the Global Regulator DasR from Streptomyces coelicolor: Implications for the Allosteric Regulation of GntR/HutC Repressors. Plos One, 11, 2016
5A7O	Crystal structure of human JMJD2A in complex with compound 42 分子名称: 1,2-ETHANEDIOL, 2-[5-(2-methoxyethanoylamino)-2-oxidanyl-phenyl]pyridine-4-carboxylic acid, DIMETHYL SULFOXIDE, ... 著者 Nowak, R, Velupillai, S, Krojer, T, Gileadi, C, Johansson, C, Korczynska, M, Le, D.D, Younger, N, Gregori-Puigjane, E, Tumber, A, Iwasa, E, Pollock, S.B, Ortiz Torres, I, Pinkas, D.M, von Delft, F, Arrowsmith, C.H, Bountra, C, Edwards, A, Shoichet, B.K, Fujimori, D.G, Oppermann, U. 登録日 2015-07-09 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Docking and Linking of Fragments to Discover Jumonji Histone Demethylase Inhibitors. J.Med.Chem., 59, 2016
3URR	Structure of PTS IIA-like nitrogen-regulatory protein PtsN (BTH_I0484) (ptsN) 分子名称: GLYCEROL, PHOSPHATE ION, PTS IIA-like nitrogen-regulatory protein PtsN 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-22 公開日 2011-12-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.397 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
3UNQ	Bovine trypsin variant X(triplePhe227) in complex with small molecule inhibitor 分子名称: 1,2-ETHANEDIOL, BENZAMIDINE, CALCIUM ION, ... 著者 Tziridis, A, Neumann, P, Kolenko, P, Stubbs, M.T. 登録日 2011-11-16 公開日 2012-11-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 Correlating structure and ligand affinity in drug discovery: a cautionary tale involving second shell residues. Biol.Chem., 395, 2014
5EKA	HU DNA-binding protein from Thermus thermophilus 分子名称: DNA-binding protein HU, GLYCEROL 著者 Papageorgiou, A, Adam, P, Stavros, P, Nounesis, G, Meijers, R, Petratos, K, Vorgias, C.E. 登録日 2015-11-03 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 HU histone-like DNA-binding protein from Thermus thermophilus: structural and evolutionary analyses. Extremophiles, 20, 2016
4ZSK	Crystal structure of the effector-binding domain of DasR (DasR-EBD) in complex with N-acetylglucosamine-6-phosphate 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, ... 著者 Fillenberg, S.B, Muller, Y.A. 登録日 2015-05-13 公開日 2016-06-08 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal Structures of the Global Regulator DasR from Streptomyces coelicolor: Implications for the Allosteric Regulation of GntR/HutC Repressors. Plos One, 11, 2016
1ZCA	Crystal structure of G alpha 12 in complex with GDP, Mg2+ and AlF4- 分子名称: G alpha i/12, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Nance, M.R, Tesmer, J.J.G. 登録日 2005-04-11 公開日 2005-11-15 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteins. Biochemistry, 45, 2006
4ZST	Crystal structure of Brevundimonas diminuta phosphotriesterase mutant L7eP-3a 分子名称: COBALT (II) ION, Parathion hydrolase 著者 Mabanglo, M.F, Raushel, F.M. 登録日 2015-05-13 公開日 2015-09-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.011 Å) 主引用文献 Variants of Phosphotriesterase for the Enhanced Detoxification of the Chemical Warfare Agent VR. Biochemistry, 54, 2015
5ELL	Crystal structure of L-aspartate/glutamate-specific racemase from Escherichia coli 分子名称: Asp/Glu_racemase family protein 著者 Ahn, J.W, Chang, J.H, Kim, K.J. 登録日 2015-11-04 公開日 2015-11-18 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Structural basis for an atypical active site of an l-aspartate/glutamate-specific racemase from Escherichia coli Febs Lett., 589, 2015
1Z6T	Structure of the apoptotic protease-activating factor 1 bound to ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Apoptotic protease activating factor 1 著者 Riedl, S.J, Li, W, Chao, Y, Schwarzenbacher, R, Shi, Y. 登録日 2005-03-23 公開日 2005-04-19 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure of the apoptotic protease-activating factor 1 bound to ADP Nature, 434, 2005
5ELY	X-ray structure of human glutamate carboxypeptidase II (GCPII) in complex with a hydroxamate inhibitor JHU242 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(2~{R})-2-carboxy-5-(oxidanylamino)-5-oxidanylidene-pentyl]benzoic acid, ... 著者 Barinka, C, Novakova, Z, Pavlicek, J. 登録日 2015-11-05 公開日 2016-04-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity. J.Med.Chem., 59, 2016
4ZVO	Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to VEID inhibitor. 分子名称: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASJ 著者 Hill, M.E, MacPherson, D.J, Hardy, J.A. 登録日 2015-05-18 公開日 2016-04-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition. Acs Chem.Biol., 11, 2016
2B55	Human cyclin dependent kinase 2 (cdk2) complexed with indenopyraxole DIN-101312 分子名称: 2-(4-(AMINOMETHYL)PIPERIDIN-1-YL)-N-(3_CYCLOHEXYL-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)ACETAMIDE, Cell division protein kinase 2 著者 Muckelbauer, J. 登録日 2005-09-27 公開日 2005-10-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Synthesis and Evaluation of Indenopyrazoles as Cyclin-Dependent Kinase Inhibitors. 3. Structure Activity Relationships at C3 J.Med.Chem., 45, 2002
5EU1	CRYSTAL STRUCTURE OF BRD9 IN COMPLEX WITH BI-7273 分子名称: 4-[4-[(dimethylamino)methyl]-3,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one, BRD9 著者 Bader, G, Martin, L.M, Steurer, S, Weiss-Puxbaum, A, Zoephel, A. 登録日 2015-11-18 公開日 2016-03-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-Based Design of an in Vivo Active Selective BRD9 Inhibitor. J.Med.Chem., 59, 2016
5EU8	Structure of FIPV main protease in complex with dual inhibitors 分子名称: 1,2-ETHANEDIOL, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE, ZINC ION, ... 著者 Wang, F, Chen, C, Liu, X, Yang, K, Xu, X, Yang, H. 登録日 2015-11-18 公開日 2015-12-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.447 Å) 主引用文献 Crystal Structure of Feline Infectious Peritonitis Virus Main Protease in Complex with Synergetic Dual Inhibitors J.Virol., 90, 2015
3UW4	Crystal structure of cIAP1 BIR3 bound to GDC0152 分子名称: Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 4, GDC0152, ... 著者 Maurer, B, Hymowitz, S. 登録日 2011-11-30 公開日 2012-02-22 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152). J.Med.Chem., 55, 2012
5EUG	CRYSTALLOGRAPHIC AND ENZYMATIC STUDIES OF AN ACTIVE SITE VARIANT H187Q OF ESCHERICHIA COLI URACIL DNA GLYCOSYLASE: CRYSTAL STRUCTURES OF MUTANT H187Q AND ITS URACIL COMPLEX 分子名称: PROTEIN (GLYCOSYLASE), URACIL 著者 Xiao, G, Tordova, M, Drohat, A.C, Jagadeesh, J, Stivers, J.T, Gilliland, G.L. 登録日 1998-12-27 公開日 1999-07-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: structure and glycosylase mechanism revisited. Proteins, 35, 1999
4ZWJ	Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser 分子名称: Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin 著者 Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR) 登録日 2015-05-19 公開日 2015-07-29 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.302 Å) 主引用文献 Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature, 523, 2015
5UJ8	Human Origin Recognition Complex subunits 2 and 3 分子名称: Origin recognition complex subunit 2, Origin recognition complex subunit 3 著者 Tocilj, A, On, K.F, Elkayam, E, Joshua-Tor, L. 登録日 2017-01-17 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (6 Å) 主引用文献 Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6, 2017
1ZI1	Crystal Structure of Human N-acetylgalactosaminyltransferase (GTA) Complexed with Lactose 分子名称: CHLORIDE ION, Histo-blood group ABO system transferase (NAGAT) Includes: Glycoprotein-fucosylgalactoside alpha-N- acetylgalactosaminyltransferase, MANGANESE (II) ION, ... 著者 Letts, J.A, Rose, N.L, Fang, Y.R, Barry, C.H, Borisova, S.N, Seto, N.O, Palcic, M.M, Evans, S.V. 登録日 2005-04-26 公開日 2005-12-13 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Differential Recognition of the Type I and II H Antigen Acceptors by the Human ABO(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem., 281, 2006

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