PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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8YDE	E.coli transcription translation coupling complex in TTC-B state 1 (subclass 3) containing mRNA with 39-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Zhang, J, Lu, G, Wang, C, Lin, J. 登録日 2024-02-20 公開日 2025-08-27 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 E.coli transcription translation coupling complex in TTC-B state 1 (subclass 3) containing mRNA with 39-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin To be published
2R8U	Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution 分子名称: MOLYBDATE ION, Microtubule-associated protein RP/EB family member 1 著者 Huang, X, Lovelace, L.L, Smith, D, Lebioda, L. 登録日 2007-09-11 公開日 2008-09-23 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution To be Published
9F1C	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Yudin, D, Scaiola, A, Ban, N. 登録日 2024-04-18 公開日 2024-08-21 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
3MBM	Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with cytosine and FoL fragment 717, imidazo[2,1-b][1,3]thiazol-6-ylmethanol 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, 6-AMINOPYRIMIDIN-2(1H)-ONE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-03-25 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011
3PZJ	Crystal structure of a probable acetyltransferases (GNAT family) from Chromobacterium violaceum ATCC 12472 分子名称: 1,2-ETHANEDIOL, Probable acetyltransferases, SODIUM ION 著者 Nocek, B, Stein, A, Bigelow, L, Feldmann, B, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2010-12-14 公開日 2011-01-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Crystal structure of a probable acetyltransferases (GNAT family) from Chromobacterium violaceum ATCC 12472 TO BE PUBLISHED
6FET	Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-1439 分子名称: 1,2-ETHANEDIOL, 1-(2-{4-[(4aS,8aR)-4-[3,4-bis(difluoromethoxy)phenyl]-1-oxo-1,2,4a,5,8,8a-hexahydrophthalazin-2-yl]piperidin-1-yl}-2-oxoethyl)-4,4-dimethylpiperidine-2,6-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Singh, A.K, Brown, D.G. 登録日 2018-01-03 公開日 2019-04-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 hPDE4D2 structure with inhibitor NPD-1439 To be published
7K20	Cryo-EM structure of pyrene-labeled ADP-actin filaments 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... 著者 Chou, S.Z, Pollard, T.D. 登録日 2020-09-08 公開日 2020-11-04 最終更新日 2025-04-02 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-electron microscopy structures of pyrene-labeled ADP-P i - and ADP-actin filaments. Nat Commun, 11, 2020
1PFU	METHIONYL-TRNA SYNTHETASE FROM ESCHERICHIA COLI COMPLEXED WITH METHIONINE PHOSPHINATE 分子名称: (1-AMINO-3-METHYLSULFANYL-PROPYL)-PHOSPHINIC ACID, Methionyl-tRNA synthetase, ZINC ION 著者 Crepin, T, Schmitt, E, Mechulam, Y, Sampson, P.B, Vaughan, M.D, Honek, J.F, Blanquet, S. 登録日 2003-05-27 公開日 2004-02-17 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Use of analogues of methionine and methionyl adenylate to sample conformational changes during catalysis in Escherichia coli methionyl-tRNA synthetase. J.Mol.Biol., 332, 2003
9F1D	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... 著者 Yudin, D, Scaiola, A, Ban, N. 登録日 2024-04-18 公開日 2024-08-21 最終更新日 2024-10-02 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
2WEW	Crystal structure of human apoM in complex with myristic acid 分子名称: 1,2-ETHANEDIOL, APOLIPOPROTEIN M, MYRISTIC ACID 著者 Sevvana, M, Ahnstrom, J, Egerer-Sieber, C, Dahlback, B, Muller, Y.A. 登録日 2009-04-02 公開日 2009-09-15 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Serendipitous Fatty Acid Binding Reveals the Structural Determinants for Ligand Recognition in Apolipoprotein M. J.Mol.Biol., 393, 2009
6JUG	Crystal Structures of Endo-beta-1,4-xylanase II Complexed with Xylotriose 分子名称: Endo-1,4-beta-xylanase 2, IODIDE ION 著者 Li, C, Wan, Q. 登録日 2019-04-13 公開日 2020-04-15 最終更新日 2025-03-12 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 Studying the Role of a Single Mutation of a Family 11 Glycoside Hydrolase Using High-Resolution X-ray Crystallography. Protein J., 39, 2020
5VX2	Mcl-1 in complex with Bim-h3Pc-RT 分子名称: 1,2-ETHANEDIOL, Bcl-2-like protein 11, Induced myeloid leukemia cell differentiation protein Mcl-1 homolog,Induced myeloid leukemia cell differentiation protein Mcl-1 chimera 著者 Cowan, A.D, Brouwer, J.M, Colman, P.M, Czabotar, P.E. 登録日 2017-05-23 公開日 2017-11-15 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.851 Å) 主引用文献 Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design. Mol. Cell, 68, 2017
2AML	Crystal structure of Lmo0035 protein (46906266) from LISTERIA MONOCYTOGENES 4b F2365 at 1.50 A resolution 分子名称: ACETATE ION, GLYCEROL, PHOSPHATE ION, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2005-08-09 公開日 2005-10-18 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Lmo0035 protein (46906266) from Listeria Monocytogenes 4b F2365 at 1.50 A resolution To be published
4APL	Crystal Structure of AMA1 from Neospora caninum 分子名称: APICAL MEMBRANE ANTIGEN 1 著者 Tonkin, M.L, Crawford, J, Lebrun, M.L, Boulanger, M.J. 登録日 2012-04-04 公開日 2012-12-05 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Babesia Divergens and Neospora Caninum Apical Membrane Antigen 1 (Ama1) Structures Reveal Selectivity and Plasticity in Apicomplexan Parasite Host Cell Invasion. Protein Sci., 22, 2013
7KKN	Structure of the catalytic domain of tankyrase 1 in complex with talazoparib 分子名称: (8S,9R)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Poly [ADP-ribose] polymerase, ... 著者 Gajiwala, K.S, Ryan, K. 登録日 2020-10-27 公開日 2021-01-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1. J.Biol.Chem., 296, 2021
9GFH	BCR Fab from the subset 1 chronic lymphocytic leukaemia case P1173 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BCR P1173 heavy chain, ... 著者 Cocomazzi, P.G, Degano, M. 登録日 2024-08-09 公開日 2025-08-20 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 Defective cell-autonomous signalling and antigenic polyreactivity of B-cell receptors from chronic lymphocytic leukaemia stereotyped subset 1 To Be Published
1MDC	CRYSTALLIZATION, STRUCTURE DETERMINATION AND LEAST-SQUARES REFINEMENT TO 1.75 ANGSTROMS RESOLUTION OF THE FATTY-ACID-BINDING PROTEIN ISOLATED FROM MANDUCA SEXTA L 分子名称: INSECT FATTY ACID BINDING PROTEIN, PALMITIC ACID, SULFATE ION 著者 Benning, M, Holden, H.M. 登録日 1992-07-20 公開日 1994-01-31 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystallization, structure determination and least-squares refinement to 1.75 A resolution of the fatty-acid-binding protein isolated from Manduca sexta L. J.Mol.Biol., 228, 1992
1TKB	SPECIFICITY OF COENZYME BINDING IN THIAMIN DIPHOSPHATE DEPENDENT ENZYMES: CRYSTAL STRUCTURES OF YEAST TRANSKETOLASE IN COMPLEX WITH ANALOGS OF THIAMIN DIPHOSPHATE 分子名称: 1'-DEAZO-THIAMIN DIPHOSPHATE, CALCIUM ION, TRANSKETOLASE 著者 Schneider, G, Koenig, S. 登録日 1994-02-07 公開日 1994-11-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Specificity of coenzyme binding in thiamin diphosphate-dependent enzymes. Crystal structures of yeast transketolase in complex with analogs of thiamin diphosphate. J.Biol.Chem., 269, 1994
7KJR	Cryo-EM structure of SARS-CoV-2 ORF3a 分子名称: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, Apolipoprotein A-I, ORF3a protein 著者 Kern, D.M, Hoel, C.M, Kotecha, A, Brohawn, S.G. 登録日 2020-10-26 公開日 2020-11-18 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (2.08 Å) 主引用文献 Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs. Nat.Struct.Mol.Biol., 28, 2021
5V37	Crystal structure of SMYD3 with SAM and EPZ028862 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... 著者 Boriack-Sjodin, P.A. 登録日 2017-03-06 公開日 2018-03-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation. Plos One, 13, 2018
6K8P	Structural and catalytic analysis of two diverse uridine phosphorylases in the oomycete Phytophthora capsici. 分子名称: 1-O-phosphono-alpha-D-ribofuranose, PHOSPHATE ION, THYMIDINE, ... 著者 Yang, C.C, Zhang, X.G. 登録日 2019-06-13 公開日 2019-11-13 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.965 Å) 主引用文献 Structural and catalytic analysis of two diverse uridine phosphorylases in Phytophthora capsici. Sci Rep, 10, 2020
6JY1	Crystal Structure of a Group II pyridoxal dependent decarboxylase, LLP-bound form from Methanocaldococcus jannaschii at 1.72 A 分子名称: GLYCEROL, L-tyrosine/L-aspartate decarboxylase, SULFATE ION 著者 Manoj, N, Gayathri, S.C. 登録日 2019-04-25 公開日 2019-10-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structural insights into the mechanism of internal aldimine formation and catalytic loop dynamics in an archaeal Group II decarboxylase. J.Struct.Biol., 208, 2019
2VZD	Crystal structure of the C-terminal calponin homology domain of alpha parvin in complex with paxillin LD1 motif 分子名称: 1,2-ETHANEDIOL, ALPHA-PARVIN, GLYCEROL, ... 著者 Lorenz, S, Vakonakis, I, Lowe, E.D, Campbell, I.D, Noble, M.E.M, Hoellerer, M.K. 登録日 2008-07-31 公開日 2008-10-28 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin Structure, 16, 2008
1PTX	CRYSTAL STRUCTURE OF TOXIN II FROM THE SCORPION ANDROCTONUS AUSTRALIS HECTOR REFINED AT 1.3 ANGSTROMS RESOLUTION 分子名称: SCORPION TOXIN II 著者 Fontecilla-Camps, J.C, Housset, D. 登録日 1994-09-02 公開日 1995-01-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of toxin II from the scorpion Androctonus australis Hector refined at 1.3 A resolution. J.Mol.Biol., 238, 1994
6KEC	Crystal structure of BRD4 bromodomain 1 (BD1) in complex with 4-ethoxy-5,16-dimethoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(17),3,5,7,9,13,15-heptaen-12-one 分子名称: 4-ethoxy-5,16-dimethoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(17),3,5,7,9,13,15-heptaen-12-one, Bromodomain-containing protein 4, FORMIC ACID 著者 Lee, B.I, Park, T.H. 登録日 2019-07-04 公開日 2020-07-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research. Molecules, 26, 2021

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