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3U1N
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BU of 3u1n by Molmil
Structure of the catalytic core of human SAMHD1
分子名称: PHOSPHATE ION, SAM domain and HD domain-containing protein 1, ZINC ION
著者Goldstone, D.C, Ennis-Adeniran, V, Walker, P.A, Haire, L.F, Webb, M, Taylor, I.A.
登録日2011-09-30
公開日2011-11-16
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase
Nature, 480, 2011
1TE6
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BU of 1te6 by Molmil
Crystal Structure of Human Neuron Specific Enolase at 1.8 angstrom
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Gamma enolase, ...
著者Chai, G, Brewer, J, Lovelace, L, Aoki, T, Minor, W, Lebioda, L.
登録日2004-05-24
公開日2004-09-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Expression, Purification and the 1.8 A Resolution Crystal Structure of Human Neuron Specific Enolase
J.Mol.Biol., 341, 2004
1TEV
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BU of 1tev by Molmil
Crystal structure of the human UMP/CMP kinase in open conformation
分子名称: SULFATE ION, UMP-CMP kinase
著者Segura-Pena, D, Sekulic, N, Ort, S, Konrad, M, Lavie, A.
登録日2004-05-25
公開日2004-06-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substrate-induced Conformational Changes in Human UMP/CMP Kinase.
J.Biol.Chem., 279, 2004
3UBW
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BU of 3ubw by Molmil
Complex of 14-3-3 isoform epsilon, a Mlf1 phosphopeptide and a small fragment hit from a FBDD screen
分子名称: (3S)-pyrrolidin-3-ol, 14-3-3 protein epsilon, Myeloid leukemia factor 1, ...
著者Molzan, M, Weyand, M, Rose, R, Ottmann, C.
登録日2011-10-25
公開日2012-01-25
最終更新日2012-02-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights of the MLF1/14-3-3 interaction.
Febs J., 279, 2012
1WJP
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BU of 1wjp by Molmil
Solution structure of zf-C2H2 domains from human Zinc finger protein 295
分子名称: ZINC ION, Zinc finger protein 295
著者Tomizawa, T, Kigawa, T, Saito, K, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-29
公開日2004-11-29
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of zf-C2H2 domains from human Zinc finger protein 295
To be Published
3U5K
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BU of 3u5k by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with Midazolam
分子名称: 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine, Bromodomain-containing protein 4
著者Filippakopoulos, P, Picaud, S, Felletar, I, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2011-10-11
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.
Bioorg.Med.Chem., 20, 2012
3TIW
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BU of 3tiw by Molmil
Crystal structure of p97N in complex with the C-terminus of gp78
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase AMFR, Transitional endoplasmic reticulum ATPase
著者Haenzelmann, P, Schindelin, H.
登録日2011-08-22
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97.
J.Biol.Chem., 286, 2011
1WWQ
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BU of 1wwq by Molmil
Solution Structure of Mouse ER
分子名称: Enhancer of rudimentary homolog
著者Li, H, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-01-12
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the mouse enhancer of rudimentary protein reveals a novel fold
J.Biomol.Nmr, 32, 2005
4FNC
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BU of 4fnc by Molmil
Human TDG in a post-reactive complex with 5-hydroxymethyluracil (5hmU)
分子名称: 5-HYDROXYMETHYL URACIL, DNA (28-MER), DNA (29-MER), ...
著者Hashimoto, H, Hong, S, Bhagwat, A.S, Zhang, X, Cheng, X.
登録日2012-06-19
公開日2012-09-19
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation.
Nucleic Acids Res., 40, 2012
3TJM
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BU of 3tjm by Molmil
Crystal Structure of the Human Fatty Acid Synthase Thioesterase Domain with an Activate Site-Specific Polyunsaturated Fatty Acyl Adduct
分子名称: Fatty acid synthase, methyl (R)-(6Z,9Z,12Z)-octadeca-6,9,12-trien-1-ylphosphonofluoridate
著者Zhang, W, Zheng, F, Florante, A.Q.
登録日2011-08-24
公開日2011-09-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid.
Proc.Natl.Acad.Sci.USA, 108, 2011
3U5J
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BU of 3u5j by Molmil
Crystal Structure of the first bromodomain of human BRD4 in complex with Alprazolam
分子名称: 1,2-ETHANEDIOL, 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, Bromodomain-containing protein 4
著者Filippakopoulos, P, Picaud, S, Felletar, I, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2011-10-11
公開日2011-11-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.
Bioorg.Med.Chem., 20, 2012
4FL9
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BU of 4fl9 by Molmil
Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Heat shock cognate 71 kDa protein, trimethylamine oxide
著者Grimm, C.
登録日2012-06-14
公開日2013-10-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution
TO BE PUBLISHED
3TLP
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BU of 3tlp by Molmil
Crystal structure of the fourth bromodomain of human poly-bromodomain containing protein 1 (PB1)
分子名称: NICKEL (II) ION, Protein polybromo-1
著者Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Krojer, T, Allerston, C.K, Latwiel, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2011-08-30
公開日2011-09-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.13 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
3TU9
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BU of 3tu9 by Molmil
Crystal structure of rabbit muscle aldolase bound with 5-O-methyl mannitol 1,6-phosphate
分子名称: 2-O-methyl-1,6-di-O-phosphono-D-mannitol, Fructose-bisphosphate aldolase A
著者Arthus-Cartier, G, Sygusch, J.
登録日2011-09-16
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Mannitol Bis-phosphate Based Inhibitors of Fructose 1,6-Bisphosphate Aldolases.
ACS Med Chem Lett, 2, 2011
1WE7
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BU of 1we7 by Molmil
Solution structure of Ubiquitin-like domain in SF3a120
分子名称: Sf3a1 protein
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-24
公開日2004-11-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of Ubiquitin-like domain in SF3a120
To be Published
1WM2
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BU of 1wm2 by Molmil
Crystal structure of human SUMO-2 protein
分子名称: Ubiquitin-like protein SMT3B
著者Huang, W.-C, Ko, T.-P, Li, S.S.-L, Wang, A.H.-J.
登録日2004-07-02
公開日2004-11-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of the human SUMO-2 protein at 1.6 A and 1.2 A resolution: implication on the functional differences of SUMO proteins
Eur.J.Biochem., 271, 2004
1WTB
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BU of 1wtb by Molmil
Complex structure of the C-terminal RNA-binding domain of hnRNP D (AUF1) with telomere DNA
分子名称: 5'-D(P*TP*AP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein D0
著者Enokizono, Y, Konishi, Y, Nagata, K, Ouhashi, K, Uesugi, S, Ishikawa, F, Katahira, M.
登録日2004-11-22
公開日2005-04-05
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of hnRNP D complexed with single-stranded telomere DNA and unfolding of the quadruplex by heterogeneous nuclear ribonucleoprotein D
J.Biol.Chem., 280, 2005
3UCD
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BU of 3ucd by Molmil
Asymmetric complex of human neuron specific enolase-2-PGA/PEP
分子名称: 2-PHOSPHOGLYCERIC ACID, Gamma-enolase, MAGNESIUM ION, ...
著者Qin, J, Chai, G, Brewer, J, Lovelace, L, Lebioda, L.
登録日2011-10-26
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Structures of asymmetric complexes of human neuron specific enolase with resolved substrate and product and an analogous complex with two inhibitors indicate subunit interaction and inhibitor cooperativity.
J.Inorg.Biochem., 111, 2012
3UF1
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BU of 3uf1 by Molmil
Crystal Structure of Vimentin (fragment 144-251) from Homo sapiens, Northeast Structural Genomics Consortium Target HR4796B
分子名称: Vimentin
著者Kuzin, A, Abashidze, M, Vorobiev, S.M, Patel, P, Xiao, R, Ciccosanti, C, Shastry, R, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2011-10-31
公開日2011-11-30
最終更新日2013-04-24
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The structure of vimentin linker 1 and rod 1B domains characterized by site-directed spin-labeling electron paramagnetic resonance (SDSL-EPR) and X-ray crystallography.
J.Biol.Chem., 287, 2012
3RCW
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BU of 3rcw by Molmil
Crystal Structure of the bromodomain of human BRD1
分子名称: 1,2-ETHANEDIOL, 1-methylpyrrolidin-2-one, ACETATE ION, ...
著者Filippakopoulos, P, Keates, T, Picaud, S, Felletar, I, Pike, A.C.W, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2011-03-31
公開日2011-06-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
1WHW
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BU of 1whw by Molmil
Solution structure of the N-terminal RNA binding domain from hypothetical protein BAB23448
分子名称: hypothetical protein RIKEN CDNA 1200009A02
著者Nagata, T, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal RNA binding domain from hypothetical protein BAB23448
To be Published
1WF0
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BU of 1wf0 by Molmil
Solution structure of RRM domain in TAR DNA-binding protein-43
分子名称: TAR DNA-binding protein-43
著者He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-25
公開日2004-11-25
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of RRM domain in TAR DNA-binding protein-43
To be Published
1WIB
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BU of 1wib by Molmil
Solution structure of the N-terminal domain from mouse hypothetical protein BAB22488
分子名称: 60S ribosomal protein L12
著者Suzuki, S, Muto, Y, Inoue, M, Kigawa, T, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal domain from mouse hypothetical protein BAB22488
To be Published
1WIZ
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BU of 1wiz by Molmil
Solution structure of the first CUT domain of KIAA1034 protein
分子名称: DNA-binding protein SATB2
著者Inoue, K, Nameki, S, Hayashi, F, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the first CUT domain of KIAA1034 protein
To be Published
3R27
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BU of 3r27 by Molmil
Crystal structure of the first RRM domain of heterogeneous nuclear ribonucleoprotein L (HnRNP L)
分子名称: GLYCEROL, Heterogeneous nuclear ribonucleoprotein L
著者Zhang, W, Liu, Y, Zeng, F, Niu, L, Teng, M, Li, X.
登録日2011-03-14
公開日2011-09-14
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Crystal structure of the first RRM domain of heterogeneous nuclear ribonucleoprotein L (HnRNP L)
To be Published

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