1TEV

Crystal structure of the human UMP/CMP kinase in open conformation

Summary for 1TEV

Entry DOI	10.2210/pdb1tev/pdb
Descriptor	UMP-CMP kinase, SULFATE ION (3 entities in total)
Functional Keywords	kinase, ploop, nmp binding region, lid region, conformational changes, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus : P30085
Total number of polymer chains	1
Total formula weight	22349.42
Authors	Segura-Pena, D.,Sekulic, N.,Ort, S.,Konrad, M.,Lavie, A. (deposition date: 2004-05-25, release date: 2004-06-22, Last modification date: 2023-08-23)
Primary citation	Sekulic, N.,Ort, S.,Konrad, M.,Lavie, A. Substrate-induced Conformational Changes in Human UMP/CMP Kinase. J.Biol.Chem., 279:33882-33889, 2004 Cited by PubMed: 15163660 DOI: 10.1074/jbc.M401989200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation