6UVG
 
 | | Crystal structure of BCL-XL bound to compound 13: (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic acid | | 分子名称: | (R)-2-(3-([1,1'-Biphenyl]-4-carbonyl)-3-(4-methylbenzyl)ureido)-3-(((3R,5R,7R)-adamantan-1-ylmethyl)sulfonyl)propanoic acid, 1,2-ETHANEDIOL, Bcl-2-like protein 1, ... | | 著者 | Roy, M.J, Lessene, G, Czabotar, P.E. | | 登録日 | 2019-11-02 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-X L and BCL-2.
J.Med.Chem., 64, 2021
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7SVU
 | | TnsBctd-TnsC-TniQ complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (28-MER), DNA (29-MER), ... | | 著者 | Park, J, Tsai, A.W.T, Kellogg, E.H. | | 登録日 | 2021-11-19 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structures of the holo CRISPR RNA-guided transposon integration complex
Nature, 613, 2023
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7SP4
 | | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 2 at 3.71A resolution | | 分子名称: | Gene 3 protein, Gene 5 protein, Gene 7 protein | | 著者 | Li, F, Cingolani, G, Hou, C, Yang, R. | | 登録日 | 2021-11-02 | | 公開日 | 2022-11-09 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
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7SPU
 | | In situ cryo-EM structure of bacteriophage Sf6 gp3:gp7:gp5 complex in conformation 1 at 3.73A resolution | | 分子名称: | Gene 3 protein, Gene 5 protein, Gene 7 protein | | 著者 | Li, F, Cingolani, G, Hou, C, Yang, R. | | 登録日 | 2021-11-03 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | | 主引用文献 | High-resolution cryo-EM structure of the Shigella virus Sf6 genome delivery tail machine.
Sci Adv, 8, 2022
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7TD8
 | | Integrin alaphIIBbeta3 complex with Tirofiban | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Zhu, J, Lin, F.-Y, Zhu, J, Springer, T.A. | | 登録日 | 2021-12-30 | | 公開日 | 2022-08-17 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors.
Cell, 185, 2022
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7ST3
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8AS0
 | | PD-1 extracellular domain in complex with Fab fragment from D12 antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ongaro, T, Scietti, L, Pluss, L, Peissert, F, Villa, A, Puca, E, De Luca, R, Neri, D, Forneris, F. | | 登録日 | 2022-08-17 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Selection of a PD-1 blocking antibody from a novel fully human phage display library.
Protein Sci., 31, 2022
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7STG
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7SWX
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7SSH
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8B0X
 | | Translating 70S ribosome in the unrotated state (P and E, tRNAs) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Fromm, S.A, O'Connor, K.M, Purdy, M, Bhatt, P.R, Loughran, G, Atkins, J.F, Jomaa, A, Mattei, S. | | 登録日 | 2022-09-08 | | 公開日 | 2022-11-30 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (1.55 Å) | | 主引用文献 | The translating bacterial ribosome at 1.55 angstrom resolution generated by cryo-EM imaging services.
Nat Commun, 14, 2023
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8AP6
 | | Trypanosoma brucei mitochondrial F1Fo ATP synthase dimer | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-{[(4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranosyl)oxy]methyl}-4-{[(3beta,9beta,14beta,17beta,25R)-spirost-5-en-3-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-alpha-D-glucopyranoside, ... | | 著者 | Muehleip, A, Gahura, O, Zikova, A, Amunts, A. | | 登録日 | 2022-08-09 | | 公開日 | 2022-12-07 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
Nat Commun, 13, 2022
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7T25
 | | OspA-Fab 319-44 complex structure | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 319-44 Fab heavy chain, ... | | 著者 | Rudolph, M.J. | | 登録日 | 2021-12-03 | | 公開日 | 2022-12-14 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural analysis of OspA-31944 complex
To Be Published
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6VIM
 | | P. putida mandelate racemase co-crystallized with phenylboronic acid | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, Mandelate racemase, ... | | 著者 | Grandinetti, L, Sharma, A.N, Bearne, S.L, St Maurice, M. | | 登録日 | 2020-01-13 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Potent Inhibition of Mandelate Racemase by Boronic Acids: Boron as a Mimic of a Carbon Acid Center.
Biochemistry, 59, 2020
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6VI0
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6VLT
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6VOP
 | | Crystal structure of YgbL, a putative aldolase/epimerase/decarboxylase from Escherichia coli | | 分子名称: | Aldolase | | 著者 | Stogios, P.J, Evdokimova, E, Di Leo, R, Savchenko, A, Joachimiak, A, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-01-31 | | 公開日 | 2020-02-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Crystal structure of YgbL, a putative aldolase/epimerase/decarboxylase from Escherichia coli
To Be Published
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8AC5
 | | Complex III2 from Yarrowia lipolytica, with decylubiquinol, oxidised, b-position | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | | 著者 | Wieferig, J.P, Kuhlbrandt, W. | | 登録日 | 2022-07-05 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM.
Iucrj, 10, 2023
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8ABI
 | | Complex III2 from Yarrowia lipolytica,antimycin A bound, int-position | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | | 著者 | Wieferig, J.P, Kuhlbrandt, W. | | 登録日 | 2022-07-04 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM.
Iucrj, 10, 2023
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8AB9
 | | Complex III2 from Yarrowia lipolytica, ascorbate-reduced, b-position | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | | 著者 | Wieferig, J.P, Kuhlbrandt, W. | | 登録日 | 2022-07-04 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM.
Iucrj, 10, 2023
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7T2B
 | | Crystal structure of the 5F TCR in complex with HLA-DP4-Ply | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ciacchi, L, Farenc, C, Petersen, J, Reid, H.H, Rossjohn, J. | | 登録日 | 2021-12-03 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
Immunity, 56, 2023
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8AB6
 | | Complex III2 from Yarrowia lipolytica, combined datasets, consensus refinement | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | | 著者 | Wieferig, J.P, Kuhlbrandt, W. | | 登録日 | 2022-07-04 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (2 Å) | | 主引用文献 | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM.
Iucrj, 10, 2023
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8ABM
 | | Complex III2 from Yarrowia lipolytica, apo, b-position | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | | 著者 | Wieferig, J.P, Kuhlbrandt, W. | | 登録日 | 2022-07-04 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM.
Iucrj, 10, 2023
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8ABA
 | | Complex III2 from Yarrowia lipolytica, ascorbate-reduced, int-position | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, CARDIOLIPIN, ... | | 著者 | Wieferig, J.P, Kuhlbrandt, W. | | 登録日 | 2022-07-04 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM.
Iucrj, 10, 2023
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8AB7
 | | Complex III2 from Yarrowia lipolytica, atovaquone and antimycin A bound | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, ... | | 著者 | Wieferig, J.P, Kuhlbrandt, W. | | 登録日 | 2022-07-04 | | 公開日 | 2023-01-11 | | 最終更新日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Analysis of the conformational heterogeneity of the Rieske iron-sulfur protein in complex III 2 by cryo-EM.
Iucrj, 10, 2023
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