7STG

Consequences of HLA single chain trimer mutations on peptide presentation and binding affinity

This is a non-PDB format compatible entry.

Summary for 7STG

• Entry DOI: 10.2210/pdb7stg/pdb
• Descriptor: RPA-related protein RADX peptide,Beta-2-microglobulin,MHC class I antigen chimera, VHH (3 entities in total)
• Functional Keywords: hla, sct, vhh, hpv, immune system, immune system-viral protein complex, immune system/viral protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 32
• Total formula weight: 960960.72

Authors

Finton, K.A.K.,Rupert, P.B. (deposition date: 2021-11-12, release date: 2022-11-23, Last modification date: 2023-10-25)

• Primary citation: Finton, K.A.K.,Rupert, P.B.,Friend, D.J.,Dinca, A.,Lovelace, E.S.,Buerger, M.,Rusnac, D.V.,Foote-McNabb, U.,Chour, W.,Heath, J.R.,Campbell, J.S.,Pierce, R.H.,Strong, R.K.; Effects of HLA single chain trimer design on peptide presentation and stability.; Front Immunol, 14:1170462-1170462, 2023; PubMed: 37207206; DOI: 10.3389/fimmu.2023.1170462

Experimental method

X-RAY DIFFRACTION (2.7 Å)