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6HBA
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BU of 6hba by Molmil
Crystal Structure of the small subunit-like domain 1 of CcmM from Synechococcus elongatus (strain PCC 7942), thiol-oxidized form
分子名称: Carbon dioxide concentrating mechanism protein CcmM
著者Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M.
登録日2018-08-10
公開日2018-12-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Rubisco condensate formation by CcmM in beta-carboxysome biogenesis.
Nature, 566, 2019
6HBC
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Structure of the repeat unit in the network formed by CcmM and Rubisco from Synechococcus elongatus
分子名称: Carbon dioxide concentrating mechanism protein CcmM, Ribulose 1,5-bisphosphate carboxylase small subunit, Ribulose bisphosphate carboxylase large chain
著者Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M.
登録日2018-08-10
公開日2018-12-12
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Rubisco condensate formation by CcmM in beta-carboxysome biogenesis.
Nature, 566, 2019
4QFS
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BU of 4qfs by Molmil
Structure of AMPK in complex with Br2-A769662core activator and STAUROSPORINE inhibitor
分子名称: 2-bromo-3-(4-bromophenyl)-4-hydroxy-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, ...
著者Calabrese, M.F, Kurumbail, R.G.
登録日2014-05-21
公開日2014-08-06
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms.
Structure, 22, 2014
4RR2
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BU of 4rr2 by Molmil
Crystal structure of human primase
分子名称: DNA primase large subunit, DNA primase small subunit, IRON/SULFUR CLUSTER, ...
著者Baranovskiy, A.G, Gu, J, Suwa, Y, Babayeva, N.D, Tahirov, T.H.
登録日2014-11-05
公開日2015-01-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of the human primase.
J.Biol.Chem., 290, 2015
6FVR
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BU of 6fvr by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with Cesium ions (Cs+)
分子名称: CESIUM ION, Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside
著者Hu, H, Delarue, M.
登録日2018-03-05
公開日2018-05-16
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (4.2 Å)
主引用文献Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6IR9
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BU of 6ir9 by Molmil
RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-1) of the nucleosome
分子名称: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
著者Ehara, H, Kujirai, T, Fujino, Y, Shirouzu, M, Kurumizaka, H, Sekine, S.
登録日2018-11-12
公開日2019-02-20
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insight into nucleosome transcription by RNA polymerase II with elongation factors.
Science, 363, 2019
6INQ
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BU of 6inq by Molmil
RNA polymerase II elongation complex stalled at SHL(-1) of the nucleosome, with foreign DNA (+1 position)
分子名称: DNA (198-MER), DNA (31-MER), DNA-directed RNA polymerase subunit, ...
著者Kujirai, T, Ehara, H, Fujino, Y, Shirouzu, M, Sekine, S, Kurumizaka, H.
登録日2018-10-26
公開日2019-04-03
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (6.9 Å)
主引用文献Structural basis of the nucleosome transition during RNA polymerase II passage.
Science, 362, 2018
6HBB
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BU of 6hbb by Molmil
Crystal Structure of the small subunit-like domain 1 of CcmM from Synechococcus elongatus (strain PCC 7942)
分子名称: Carbon dioxide concentrating mechanism protein CcmM, SULFATE ION
著者Wang, H, Yan, X, Aigner, H, Bracher, A, Nguyen, N.D, Hee, W.Y, Long, B.M, Price, G.D, Hartl, F.U, Hayer-Hartl, M.
登録日2018-08-10
公開日2018-12-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Rubisco condensate formation by CcmM in beta-carboxysome biogenesis.
Nature, 566, 2019
6HEG
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BU of 6heg by Molmil
Crystal structure of Escherichia coli DEAH/RHA helicase HrpB
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase HrpB, PHOSPHATE ION, ...
著者Xin, B.G, Chen, W.F, Rety, S, Dai, Y.X, Xi, X.G.
登録日2018-08-20
公開日2018-09-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.019 Å)
主引用文献Crystal structure of Escherichia coli DEAH/RHA helicase HrpB.
Biochem. Biophys. Res. Commun., 504, 2018
6IP6
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BU of 6ip6 by Molmil
Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii)
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T.
登録日2018-11-02
公開日2019-05-29
最終更新日2019-11-06
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
6MI0
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BU of 6mi0 by Molmil
Crystal structure of the P450 domain of the CYP51-ferredoxin fusion protein from Methylococcus capsulatus, ligand-free state
分子名称: Cytochrome P450 51, PROTOPORPHYRIN IX CONTAINING FE
著者Hargrove, T, Wawrzak, Z, Lamb, D.C, Lepesheva, G.I.
登録日2018-09-18
公開日2019-07-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Concerning P450 evolution: Structural Analyses Support Bacterial Origin of Sterol 14 alpha-Demethylases.
Mol.Biol.Evol., 2020
5WGP
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BU of 5wgp by Molmil
Human Carbonic Anhydrase IX-mimic complexed with AceK
分子名称: Acesulfame, Carbonic anhydrase 2, ZINC ION
著者Murray, A.B, Lomelino, C.L, Supuran, C.T, McKenna, R.
登録日2017-07-14
公開日2018-02-07
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献"Seriously Sweet": Acesulfame K Exhibits Selective Inhibition Using Alternative Binding Modes in Carbonic Anhydrase Isoforms.
J. Med. Chem., 61, 2018
1MSH
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BU of 1msh by Molmil
SOLUTION STRUCTURE OF GRO(SLASH)MELANOMA GROWTH STIMULATORY ACTIVITY DETERMINED BY 1H NMR SPECTROSCOPY
分子名称: HUMAN MELANOMA GROWTH STIMULATORY ACTIVITY
著者Kim, K.-S, Clark-Lewis, I, Sykes, B.D.
登録日1995-01-25
公開日1995-03-31
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Solution structure of GRO/melanoma growth stimulatory activity determined by 1H NMR spectroscopy.
J.Biol.Chem., 269, 1994
5WEX
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BU of 5wex by Molmil
Discovery of new selenoureido analogs of 4-(4-fluorophenylureido) benzenesulfonamides as carbonic anhydrase inhibitors
分子名称: 4-{[(4-fluorophenyl)carbamothioyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者Angeli, A, Tanini, D, Peat, T.S, Di Cesare Mannelli, L, Bartolucci, G, Capperucci, A, Ghelardini, C, Supuran, C.T, Carta, F.
登録日2017-07-10
公開日2017-10-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Discovery of New Selenoureido Analogues of 4-(4-Fluorophenylureido)benzenesulfonamide as Carbonic Anhydrase Inhibitors.
ACS Med Chem Lett, 8, 2017
1NTL
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BU of 1ntl by Molmil
Model of mouse Crry-Ig determined by solution scattering, curve fitting and homology modelling
分子名称: Complement component receptor 1-like protein,Ig gamma-1 chain C region secreted form
著者Aslam, M, Guthridge, J.M, Hack, B.K, Quigg, R.J, Holers, V.M, Perkins, S.J.
登録日2003-01-30
公開日2004-02-03
最終更新日2024-02-14
実験手法SOLUTION SCATTERING (30 Å)
主引用文献The extended multidomain solution structures of the complement protein Crry and its chimaeric conjugate Crry-Ig by scattering, analytical ultracentrifugation and constrained modelling: implications for function and therapy
J.Mol.Biol., 329, 2003
1NYN
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BU of 1nyn by Molmil
Solution NMR Structure of Protein YHR087W from Saccharomyces cerevisiae. Northeast Structural Genomics Consortium Target YTYST425.
分子名称: Hypothetical 12.0 kDa protein in NAM8-GAR1 intergenic region
著者Cort, J.R, Yee, A.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG)
登録日2003-02-13
公開日2003-04-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.
J.Biol.Chem., 280, 2005
1O0D
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BU of 1o0d by Molmil
Human Thrombin complexed with a d-Phe-Pro-Arg-type Inhibitor and a C-terminal Hirudin derived exo-site inhibitor
分子名称: (2-{2-[(5-CARBAMIMIDOYL-1-METHYL-1H-PYRROL-2-YLMETHYL)-CARBAMOYL]-PYRROL-1-YL}- 1-CYCLOHEXYLMETHYL-2-OXO-ETHYLAMINO)-ACETIC ACID, Decapeptide Hirudin Analogue, Thrombin heavy chain, ...
著者Lange, U.E, Bauke, D, Hornberger, W, Mack, H, Seitz, W, Hoeffken, H.W.
登録日2003-02-21
公開日2003-10-14
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献D-Phe-Pro-Arg type thrombin inhibitors: unexpected selectivity by modification of the P1 moiety
Bioorg.Med.Chem.Lett., 13, 2003
2RMW
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BU of 2rmw by Molmil
Solution structure of synthetic 26-mer peptide containing 142-166 sheep prion protein segment and C-terminal cysteine with R156A mutation
分子名称: Major prion protein
著者Bertho, G, Bouvier, G, Hui Bon Hoa, G, Girault, J.-P.
登録日2007-11-29
公開日2007-12-18
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Key role of the residue 155 in the mechanism of prion transconformation highlighted by the study of sheep mutant peptides
To be Published
1NTJ
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BU of 1ntj by Molmil
Model of rat Crry determined by solution scattering, curve fitting and homology modelling
分子名称: complement receptor related protein
著者Aslam, M, Guthridge, J.M, Hack, B.K, Quigg, R.J, Holers, V.M, Perkins, S.J.
登録日2003-01-30
公開日2004-02-03
最終更新日2024-02-14
実験手法SOLUTION SCATTERING (30 Å)
主引用文献The Extended Multidomain Solution Structures of the Complement Protein Crry and its Chimeric Conjugate Crry-Ig by Scattering, Analytical Ultracentrifugation and Constrained Modelling: Implications for Function and Therapy
J.Mol.Biol., 329, 2003
4PAD
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BU of 4pad by Molmil
Binding of chloromethyl ketone substrate analogues to crystalline papain
分子名称: N-[(1S)-5-amino-1-(chloroacetyl)pentyl]-4-methylbenzenesulfonamide, PAPAIN
著者Drenth, J.
登録日1976-11-01
公開日1977-04-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Binding of chloromethyl ketone substrate analogues to crystalline papain.
Biochemistry, 15, 1976
4PKX
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BU of 4pkx by Molmil
The structure of a conserved Piezo channel domain reveals a novel beta sandwich fold
分子名称: Protein C10C5.1, isoform i
著者Kamajaya, A, Kaiser, J, Lee, J, Reid, M, Rees, D.C.
登録日2014-05-15
公開日2014-10-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献The Structure of a Conserved Piezo Channel Domain Reveals a Topologically Distinct beta Sandwich Fold.
Structure, 22, 2014
8IFD
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BU of 8ifd by Molmil
Dibekacin-added human 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.59 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
8IFE
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BU of 8ife by Molmil
Arbekacin-added human 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
著者Tomono, J, Asano, K, Chiashi, T, Tanaka, Y, Yokoyama, T.
登録日2023-02-17
公開日2024-02-14
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Direct visualization of ribosomes in the cell-free system revealed the functional evolution of aminoglycoside.
J.Biochem., 175, 2024
5XEW
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BU of 5xew by Molmil
Crystal structure of the [Ni2+-(chromomycin A3)2]-CCG repeats complex
分子名称: (1S)-5-deoxy-1-O-methyl-1-C-[(2R,3S)-3,5,7,10-tetrahydroxy-6-methyl-4-oxo-1,2,3,4-tetrahydroanthracen-2-yl]-D-xylulose, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ...
著者Tseng, W.H, Wu, P.C, Hou, M.H.
登録日2017-04-06
公開日2017-06-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献Induced-Fit Recognition of CCG Trinucleotide Repeats by a Nickel-Chromomycin Complex Resulting in Large-Scale DNA Deformation
Angew. Chem. Int. Ed. Engl., 56, 2017
6ND1
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BU of 6nd1 by Molmil
CryoEM structure of the Sec Complex from yeast
分子名称: Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ...
著者Wu, X, Cabanos, C, Rapoport, T.A.
登録日2018-12-13
公開日2019-01-09
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structure of the post-translational protein translocation machinery of the ER membrane.
Nature, 566, 2019

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