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6MI0

Crystal structure of the P450 domain of the CYP51-ferredoxin fusion protein from Methylococcus capsulatus, ligand-free state

Summary for 6MI0
Entry DOI10.2210/pdb6mi0/pdb
DescriptorCytochrome P450 51, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywordscytochrome p450 fold, cyp51, heme, sterol biosynthesis, oxidoreductase
Biological sourceMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Total number of polymer chains1
Total formula weight52363.25
Authors
Hargrove, T.,Wawrzak, Z.,Lamb, D.C.,Lepesheva, G.I. (deposition date: 2018-09-18, release date: 2019-07-10, Last modification date: 2023-10-11)
Primary citationLamb, D.C.,Hargrove, T.Y.,Zhao, B.,Wawrzak, Z.,Goldstone, J.V.,Nes, W.D.,Kelly, S.L.,Waterman, M.R.,Stegeman, J.J.,Lepesheva, G.I.
Concerning P450 evolution: Structural Analyses Support Bacterial Origin of Sterol 14 alpha-Demethylases.
Mol.Biol.Evol., 2020
Cited by
PubMed: 33031537
DOI: 10.1093/molbev/msaa260
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.73 Å)
Structure validation

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