4D1T
 
 | | High resolution structure of native tVIM-7 from Pseudomonas aeruginosa | | 分子名称: | METALLO-B-LACTAMASE, ZINC ION | | 著者 | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | 登録日 | 2014-05-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
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4D1V
 | | A F218Y mutant of VIM-7 from Pseudomonas aeruginosa | | 分子名称: | METALLO-B-LACTAMASE, ZINC ION | | 著者 | Leiros, H.-K.S, Skagseth, S, Edvardsen, K.S.W, Lorentzen, M.S, Bjerga, G.E.K, Leiros, I, Samuelsen, O. | | 登録日 | 2014-05-05 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7.
Antimicrob.Agents Chemother., 58, 2014
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7NBW
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7VT7
 | | Crystal structure of CBM deleted MtGlu5 in complex with CBI | | 分子名称: | Endoglucanase H, GLYCEROL, TRYPTOPHAN, ... | | 著者 | Ye, T.J, Ko, P.T, Huang, K.F, Wu, S.H. | | 登録日 | 2021-10-28 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase.
Acta Crystallogr D Struct Biol, 78, 2022
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7VT8
 | | Crystal structure of MtGlu5 from Meiothermus taiwanensis WR-220 | | 分子名称: | Endoglucanase H, SULFATE ION, beta-D-glucopyranose | | 著者 | Ye, T.J, Ko, P.T, Huang, K.F, Wu, S.H. | | 登録日 | 2021-10-28 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase.
Acta Crystallogr D Struct Biol, 78, 2022
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7VT4
 | | Crystal structure of mutant E393Q of MtGlu5 | | 分子名称: | Endoglucanase H, GLYCEROL, SULFATE ION | | 著者 | Ye, T.J, Ko, P.T, Huang, K.F, Wu, S.H. | | 登録日 | 2021-10-28 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase.
Acta Crystallogr D Struct Biol, 78, 2022
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7VT5
 | | Crystal structure of CBM deleted MtGlu5 from Meiothermus taiwanensis WR-220 | | 分子名称: | Endoglucanase H, METHIONINE, TRYPTOPHAN | | 著者 | Ye, T.J, Ko, P.T, Huang, K.F, Wu, S.H. | | 登録日 | 2021-10-28 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase.
Acta Crystallogr D Struct Biol, 78, 2022
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7VT6
 | | Crystal structure of CBM deleted MtGlu5 in complex with BGC. | | 分子名称: | Endoglucanase H, GLYCEROL, TRYPTOPHAN, ... | | 著者 | Ye, T.J, Ko, P.T, Huang, K.F, Wu, S.H. | | 登録日 | 2021-10-28 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Synergic action of an inserted carbohydrate-binding module in a glycoside hydrolase family 5 endoglucanase.
Acta Crystallogr D Struct Biol, 78, 2022
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5IXJ
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5J6D
 | | Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-[(N-{[2-(3-methoxyphenoxy)-6-(piperidin-1-yl)phenyl]methyl}carbamimidoyl)carbamoyl]-L-phenylalanine, FE (III) ION, ... | | 著者 | Stein, A.J, Goldberg, D.R, De Lombaert, S. | | 登録日 | 2016-04-04 | | 公開日 | 2016-05-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Discovery of acyl guanidine tryptophan hydroxylase-1 inhibitors.
Bioorg.Med.Chem.Lett., 26, 2016
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8PFK
 | | RNA structure with 1-methylpseudoridine, C2 space group | | 分子名称: | MAGNESIUM ION, RNA (12-mer) | | 著者 | Spingler, B, McAuley, K, Nievergelt, P, Thorn, A. | | 登録日 | 2023-06-16 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.321 Å) | | 主引用文献 | RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines.
Chemmedchem, 19, 2024
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8PFQ
 | | RNA structure with 1-methylpseudoridine, P1 space group | | 分子名称: | Chains: A,B, MAGNESIUM ION | | 著者 | Spingler, B, McAuley, K, Nievergelt, P, Thorn, A. | | 登録日 | 2023-06-16 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.01 Å) | | 主引用文献 | RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines.
Chemmedchem, 19, 2024
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4CMP
 | | Crystal structure of S. pyogenes Cas9 | | 分子名称: | CRISPR-ASSOCIATED ENDONUCLEASE CAS9/CSN1, MAGNESIUM ION, SULFATE ION | | 著者 | Jinek, M, Jiang, F, Taylor, D.W, Sternberg, S.H, Kaya, E, Ma, E, Anders, C, Hauer, M, Zhou, K, Lin, S, Kaplan, M, Iavarone, A.T, Charpentier, E, Nogales, E, Doudna, J.A. | | 登録日 | 2014-01-16 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation.
Science, 343, 2014
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7WD0
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7WDF
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7WD9
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7WD7
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7WCR
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7WCZ
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7WD8
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4P5M
 | | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Wang, Y, Dai, S, Kappler, J. | | 登録日 | 2014-03-18 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.
Cell, 158, 2014
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3KGF
 | | The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan | | 分子名称: | CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Parker, E.J, Jameson, G.B, Jiao, W, Webby, C.J, Baker, E.N, Baker, H.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) | | 登録日 | 2009-10-29 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
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8G4G
 | | Crystal Engineering with One 8-mer DNA | | 分子名称: | DNA (5'-D(*AP*TP*CP*GP*G)-3'), DNA (5'-D(*AP*TP*CP*GP*GP*CP*CP*G)-3'), DNA (5'-D(P*CP*CP*G)-3') | | 著者 | Zhao, J, Zhang, C, Lu, B, Seeman, N.C, Noinaj, N, Sha, R, Mao, C. | | 登録日 | 2023-02-09 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Divergence and Convergence: Complexity Emerges in Crystal Engineering from an 8-mer DNA.
J.Am.Chem.Soc., 145, 2023
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8CYI
 | | Cryo-EM structures and computational analysis for enhanced potency in MTA-synergic inhibition of human protein arginine methyltransferase 5 | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein 50, N-[(2-aminoquinolin-7-yl)methyl]-9-(2-hydroxyethyl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide, ... | | 著者 | Yadav, G.P, Wei, Z, Xiaozhi, Y, Chenglong, L, Jiang, Q. | | 登録日 | 2022-05-23 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Cryo-EM structure-based selection of computed ligand poses enables design of MTA-synergic PRMT5 inhibitors of better potency.
Commun Biol, 5, 2022
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7P9T
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