PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

---

3HJC	Crystal structure of the carboxy-terminal domain of HSP90 from Leishmania major, LmjF33.0312 分子名称: Heat shock protein 83-1, SULFATE ION 著者 Wernimont, A.K, Tempel, W, Walker, J, Lin, Y.H, Hutchinson, A, Mackenzie, F, Fairlamb, A, Kozieradzki, I, Cossar, D, Zhao, Y, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Ferguson, M.A.J, Hui, R, Pizarro, J.C, Hills, T, Structural Genomics Consortium (SGC) 登録日 2009-05-21 公開日 2009-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of the middle and carboxy-terminal domain of HSP90 from Leishmania major, LMJF33.0312 To be Published
3HJY	Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA 分子名称: 5'-R(*GP*GP*AP*GP*CP*GP*UP*GP*CP*GP*GP*UP*UP*U)-3', 5'-R(*GP*GP*GP*CP*UP*CP*CP*GP*GP*AP*AP*AP*CP*CP*GP*CP*GP*GP*CP*GP*C)-3', RNA (25-MER), ... 著者 Liang, B, Zhou, J, Kahen, E, Terns, R.M, Terns, M.P, Li, H. 登録日 2009-05-22 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.65 Å) 主引用文献 Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA Nat.Struct.Mol.Biol., 16, 2009
6QXL	Crystal Structure of Pyruvate Kinase II (PykA) from Pseudomonas aeruginosa in complex with sodium malonate, magnesium and glucose-6-phosphate 分子名称: 6-O-phosphono-alpha-D-glucopyranose, GLYCEROL, MAGNESIUM ION, ... 著者 Abdelhamid, Y, Brear, P, Welch, M. 登録日 2019-03-07 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Evolutionary plasticity in the allosteric regulator-binding site of pyruvate kinase isoform PykA fromPseudomonas aeruginosa. J.Biol.Chem., 294, 2019
3HJW	Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA 分子名称: 5'-R(*GP*AP*GP*CP*GP*(FHU)P*GP*CP*GP*GP*UP*UP*U)-3', 50S ribosomal protein L7Ae, POTASSIUM ION, ... 著者 Liang, B, Zhou, J, Kahen, E, Terns, R.M, Terns, M.P, Li, H. 登録日 2009-05-22 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA Nat.Struct.Mol.Biol., 16, 2009
3USC	Crystal Structure of E. coli hydrogenase-1 in a ferricyanide-oxidized form 分子名称: CARBONMONOXIDE-(DICYANO) IRON, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... 著者 Volbeda, A, Fontecilla-Camps, J.C, Darnault, C. 登録日 2011-11-23 公開日 2012-03-28 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystallographic and computational studies of the O2-tolerant [NiFe]-hydrogenase 1 from Escherichia coli. Proc.Natl.Acad.Sci.USA, 109, 2012
3UTG	Crystal structure of Aspergillus fumigatus UDP galactopyranose mutase complexed with UDP in reduced state 分子名称: DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION, UDP-galactopyranose mutase, ... 著者 Dhatwalia, R, Singh, H, Tanner, J.J. 登録日 2011-11-25 公開日 2012-02-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic Fungus Aspergillus fumigatus. J.Biol.Chem., 287, 2012
3UV2	Crystal structure of the bromodomain of human nucleosome-remodeling factor subunit BPTF 分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, bromodomain of human nucleosome-remodeling factor subunit BPTF 著者 Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-11-29 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
3UVC	MMP12 in a complex with the dimeric adduct: 5-(5-phenylhydantoin)-5-phenylhydantoin 分子名称: (4R,4'S)-4,4'-diphenyl-4,4'-biimidazolidine-2,2',5,5'-tetrone, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Derbyshire, D.J, Danielson, H, Nystrum, S. 登録日 2011-11-29 公開日 2013-01-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Characterization of fragments interacting with MMP-12 To be Published
3HKK	Structure of human Leukotriene C4 synthase in complex with glutathione sulfonate 分子名称: GLUTATHIONE SULFONIC ACID, Leukotriene C4 synthase, PALMITIC ACID, ... 著者 Rinaldo-Matthis, A, Haeggstrom, J.Z. 登録日 2009-05-24 公開日 2010-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Pre-steady state kinetics of human Leukotriene C4 synthase To be Published
3V1L	Crystal Structure of the S112A/H265Q mutant of a C-C hydrolase, BphD from Burkholderia xenovorans LB400 分子名称: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, MALONIC ACID 著者 Ghosh, S, Bolin, J.T. 登録日 2011-12-09 公開日 2012-03-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad. J.Am.Chem.Soc., 134, 2012
3UY6	BlaR1 sensor domain from Staphylococcus aureus with N439V mutation 分子名称: GLYCEROL, Regulatory protein BlaR1, SULFATE ION 著者 Baker, B.M, Borbulevych, O.Y. 登録日 2011-12-05 公開日 2012-02-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 An amino acid position at crossroads of evolution of protein function: antibiotic sensor domain of BlaR1 protein from Staphylococcus aureus versus clasS D beta-lactamases J.Biol.Chem., 287, 2012
3V2J	Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II 分子名称: 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 2, ZINC ION 著者 Aggarwal, M, McKenna, A. 登録日 2011-12-12 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.699 Å) 主引用文献 Effect of Sucrose and Glycerol as Cryoprotectans, on the Inhibition of Human Carbonic Anhydrase II To be Published
3V3F	Kinetic and structural studies of thermostabilized mutants of HCA II. 分子名称: CHLORIDE ION, Carbonic anhydrase 2, ZINC ION 著者 Boone, C.D, Fisher, S.Z, McKenna, R. 登録日 2011-12-13 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II. Protein Eng.Des.Sel., 25, 2012
3V4M	Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution 分子名称: CHLORIDE ION, SODIUM ION, Splicing factor U2AF 65 kDa subunit 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-12-15 公開日 2012-06-13 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a RNA binding domain of a U2 small nuclear ribonucleoprotein auxiliary factor 2 (U2AF) from Mus musculus at 1.80 A resolution To be published
3V3J	Kinetic and structural studies of thermostabilized mutants of HCA II. 分子名称: Carbonic anhydrase 2, ZINC ION 著者 Boone, C.D, Fisher, S.Z, McKenna, R. 登録日 2011-12-13 公開日 2012-06-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Kinetic and structural characterization of thermostabilized mutants of human carbonic anhydrase II. Protein Eng.Des.Sel., 25, 2012
3HKO	Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40 分子名称: Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands, GLYCEROL, MAGNESIUM ION, ... 著者 Wernimont, A.K, Hutchinson, A, Wasney, G, Vedadi, M, MacKenzie, F, Kozieradzki, I, Cossar, D, Weigelt, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Botchkarev, A, Hui, R, Artz, J.D, Amani, M, Structural Genomics Consortium (SGC) 登録日 2009-05-25 公開日 2009-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of a cdpk kinase domain from cryptosporidium Parvum, cgd7_40 To be Published
3V4Z	D-alanine--D-alanine ligase from Yersinia pestis 分子名称: D-alanine--D-alanine ligase, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL 著者 Osipiuk, J, Nocek, B, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-12-15 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 D-alanine--D-alanine ligase from Yersinia pestis. To be Published
3V58	Crystal Structure of the B-phycoerythrin from the red algae Porphyridium Cruentum at pH5 分子名称: PHYCOERYTHROBILIN, Phycoerythrin alpha subunit, Phycoerythrin beta subunit, ... 著者 Camara-Artigas, A. 登録日 2011-12-16 公開日 2012-10-03 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 pH-dependent structural conformations of B-phycoerythrin from Porphyridium cruentum Febs J., 279, 2012
3HR8	Crystal Structure of Thermotoga maritima RecA 分子名称: Protein recA 著者 Lee, S, Kim, T.G, Jeong, E.-Y, Ban, C, Jeon, W.-J, Min, K.I, Song, K.-M, Heo, S.-D, Ku, J.K. 登録日 2009-06-09 公開日 2010-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal Structure of RecA Protein from Thermotoga maritima MSB8 to be published
3V5T	Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1) in complex with inhibitor UW1299 分子名称: 1-[(2S)-2-(dimethylamino)-3-methylbutyl]-3-(6-ethoxynaphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 著者 Merritt, E.A, Larson, E.T. 登録日 2011-12-16 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Multiple Determinants for Selective Inhibition of Apicomplexan Calcium-Dependent Protein Kinase CDPK1. J.Med.Chem., 55, 2012
8T5K	Crystal structure of STING CTD in complex with BDW-OH 分子名称: Stimulator of interferon genes protein, {[(4S)-8,9-dimethylthieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidin-3-yl]sulfanyl}acetic acid 著者 Li, Y, Li, P, Sun, D. 登録日 2023-06-13 公開日 2023-07-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING A230 Variants. Biorxiv, 2023
8T5L	Crystal structure of STING CTD in complex with 2'3'-cGAMP 分子名称: Stimulator of interferon genes protein, cGAMP 著者 Li, Y, Li, P, Sun, D. 登録日 2023-06-13 公開日 2023-07-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING A230 Variants. Biorxiv, 2023
6D3X	Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma 分子名称: Plasminogen, Trypsin inhibitor 1 著者 Law, R.H.P, Wu, G. 登録日 2018-04-17 公開日 2019-01-23 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma. J. Med. Chem., 62, 2019
8STH	human STING with diABZI agonist 15 分子名称: 1-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-methoxy-1H-benzimidazole-5-carboxamide, Stimulator of interferon genes protein 著者 Duvall, J.R, Bukhalid, R.A. 登録日 2023-05-10 公開日 2023-07-26 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. J.Med.Chem., 66, 2023
8STI	human STING with agonist XMT-1616 分子名称: 3-[(2E)-4-{5-carbamoyl-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-7-(3-hydroxypropoxy)-1H-benzimidazol-1-yl}but-2-en-1-yl]-2-[(4-ethyl-2-methyl-1,3-oxazole-5-carbonyl)amino]-3H-imidazo[4,5-b]pyridine-6-carboxamide, Stimulator of interferon genes protein 著者 Duvall, J.R, Bukhalid, R.A. 登録日 2023-05-10 公開日 2023-07-26 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. J.Med.Chem., 66, 2023

<104105106107108109110111112113114115116117118119>