7NZ9

Crystal structure of mouse ADAT2/ADAT3 tRNA deamination complex V128L mutant

Summary for 7NZ9

Entry DOI	10.2210/pdb7nz9/pdb
Descriptor	tRNA-specific adenosine deaminase 2, Probable inactive tRNA-specific adenosine deaminase-like protein 3, ZINC ION, ... (4 entities in total)
Functional Keywords	trna modification, wobble adenine, inosine, adat, intellectual disability, neurological disorders, hydrolase
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	2
Total formula weight	55702.23
Authors	Ramos Morales, E.,Romier, C. (deposition date: 2021-03-23, release date: 2021-05-05, Last modification date: 2024-01-31)
Primary citation	Ramos-Morales, E.,Bayam, E.,Del-Pozo-Rodriguez, J.,Salinas-Giege, T.,Marek, M.,Tilly, P.,Wolff, P.,Troesch, E.,Ennifar, E.,Drouard, L.,Godin, J.D.,Romier, C. The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination. Nucleic Acids Res., 49:6529-6548, 2021 Cited by PubMed: 34057470 DOI: 10.1093/nar/gkab436 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation