7NZ9
Crystal structure of mouse ADAT2/ADAT3 tRNA deamination complex V128L mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | tRNA-specific adenosine deaminase 2 | polymer | 191 | 21333.5 | 1 | UniProt (Q6P6J0) Pfam (PF14437) | Mus musculus (Mouse) | Deaminase domain-containing protein 1,tRNA-specific adenosine-34 deaminase subunit ADAT2 |
| 2 | B (B) | Probable inactive tRNA-specific adenosine deaminase-like protein 3 | polymer | 317 | 34238.0 | 1 | UniProt (Q6PAT0) Pfam (PF00383) | Mus musculus (Mouse) | tRNA-specific adenosine-34 deaminase subunit ADAT3 |
| 3 | C, D (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, F (A, B) | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
B: 1 - 349 (UniProt: Q6PAT0)
| PDB | External Database | Details |
|---|---|---|
| Leu 128 | Val 128 | engineered mutation |
| - | Arg 238 | deletion |
| - | Gly 239 | deletion |
| - | Ser 240 | deletion |
| - | Cys 241 | deletion |
| - | Asp 242 | deletion |
| - | Leu 243 | deletion |
| - | Arg 244 | deletion |
| - | Ser 245 | deletion |
| - | His 246 | deletion |
| - | Pro 247 | deletion |
| - | Ala 248 | deletion |
| - | Cys 249 | deletion |
| - | Ser 250 | deletion |
| - | Phe 251 | deletion |
| - | Thr 252 | deletion |
| - | Gln 253 | deletion |
| - | Ala 254 | deletion |
| - | Thr 255 | deletion |
| - | Ala 256 | deletion |
| - | Thr 257 | deletion |
| - | Gln 258 | deletion |
| - | Gly 259 | deletion |
| - | Ala 260 | deletion |
| - | Arg 261 | deletion |
| - | Ala 262 | deletion |
| - | Gly 263 | deletion |
| - | Ser 264 | deletion |
| - | Val 265 | deletion |
| - | Arg 266 | deletion |
| - | Lys 267 | deletion |
| - | Leu 268 | deletion |
| - | Asp 269 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 55571.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 55702.2 |
