7O56

X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element solved by Phosphorus and Sulphur SAD methods

Summary for 7O56

• Entry DOI: 10.2210/pdb7o56/pdb
• Descriptor: Interferon regulatory factor 4, DNA (5'-D(P*AP*AP*TP*AP*AP*AP*AP*GP*AP*AP*AP*CP*CP*GP*AP*AP*AP*GP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*AP*CP*TP*TP*TP*CP*GP*GP*TP*TP*TP*CP*TP*TP*TP*TP*AP*T)-3') (3 entities in total)
• Functional Keywords: interferon regulatory factors, transcription regulation, protein-dna interaction, transcription, dna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 61799.83

Authors

El Omari, K.,Agnarelli, A.,Duman, R.,Wagner, A.,Mancini, E.J. (deposition date: 2021-04-07, release date: 2021-05-12, Last modification date: 2021-10-13)

• Primary citation: Agnarelli, A.,El Omari, K.,Duman, R.,Wagner, A.,Mancini, E.J.; Phosphorus and sulfur SAD phasing of the nucleic acid-bound DNA-binding domain of interferon regulatory factor 4.; Acta Crystallogr.,Sect.F, 77:202-207, 2021; PubMed: 34196610; DOI: 10.1107/S2053230X21006506

Experimental method

X-RAY DIFFRACTION (2.6 Å)