7O56

X-ray Structure of Interferon Regulatory Factor 4 DNA binding domain bound to an interferon-stimulated response element solved by Phosphorus and Sulphur SAD methods

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0006355	biological_process	regulation of DNA-templated transcription
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00601
Number of Residues	34
Details	IRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WeNeeksiFrIPWkHagkqdynreeDaaLFKaWA

Chain	Residue	Details
A	TRP42-ALA75

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	216
Details	DNA binding: {"description":"IRF tryptophan pentad repeat","evidences":[{"source":"PROSITE-ProRule","id":"PRU00840","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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