7NZ7

Crystal structure of mouse ADAT2/ADAT3 tRNA deamination complex 1

Summary for 7NZ7

• Entry DOI: 10.2210/pdb7nz7/pdb
• Descriptor: tRNA-specific adenosine deaminase 2, Probable inactive tRNA-specific adenosine deaminase-like protein 3, ZINC ION, ... (4 entities in total)
• Functional Keywords: trna modification, wobble adenine, inosine, adat, intellectual disability, neurological disorders, hydrolase
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 2
• Total formula weight: 55688.21

Authors

Ramos Morales, E.,Romier, C. (deposition date: 2021-03-23, release date: 2021-05-05, Last modification date: 2024-01-31)

• Primary citation: Ramos-Morales, E.,Bayam, E.,Del-Pozo-Rodriguez, J.,Salinas-Giege, T.,Marek, M.,Tilly, P.,Wolff, P.,Troesch, E.,Ennifar, E.,Drouard, L.,Godin, J.D.,Romier, C.; The structure of the mouse ADAT2/ADAT3 complex reveals the molecular basis for mammalian tRNA wobble adenosine-to-inosine deamination.; Nucleic Acids Res., 49:6529-6548, 2021; PubMed: 34057470; DOI: 10.1093/nar/gkab436

Experimental method

X-RAY DIFFRACTION (2.96 Å)