8HL2
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8HR3
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![BU of 8hr3 by Molmil](/molmil-images/mine/8hr3) | [D-Cys5,Asp7,Val8,D-Lys16]-STp(5-17) | 分子名称: | DCY-CYS-ASP-VAL-CYS-CYS-ASN-PRO-ALA-CYS-ALA-DLY-CYS | 著者 | Shimamoto, S, Hidaka, Y, Yoshino, S, Goto, M. | 登録日 | 2022-12-14 | 公開日 | 2023-09-20 | 実験手法 | SOLUTION NMR | 主引用文献 | The Molecular Basis of Heat-Stable Enterotoxin for Vaccine Development and Cancer Cell Detection. Molecules, 28, 2023
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8TTZ
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![BU of 8ttz by Molmil](/molmil-images/mine/8ttz) | Crystal structure of monkey TLR7 ectodomain with compound 20 | 分子名称: | (3S)-3-({5-amino-1-[(2-methoxy-4-{[(oxan-4-yl)amino]methyl}phenyl)methyl]-1H-pyrazolo[4,3-d]pyrimidin-7-yl}amino)hexan-1-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Critton, D.A. | 登録日 | 2023-08-15 | 公開日 | 2024-02-07 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | Discovery of Novel TLR7 Agonists as Systemic Agent for Combination With aPD1 for Use in Immuno-oncology. Acs Med.Chem.Lett., 15, 2024
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8GZ9
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8C3G
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![BU of 8c3g by Molmil](/molmil-images/mine/8c3g) | Crystal structure of DYRK1A in complex with AZ191 | 分子名称: | 1,2-ETHANEDIOL, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, N-[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]-4-(1-methylpyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine, ... | 著者 | Grygier, P, Pustelny, K, Dubin, G, Czarna, A. | 登録日 | 2022-12-23 | 公開日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural perspective on the design of selective DYRK1B inhibitors To Be Published
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8HJV
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![BU of 8hjv by Molmil](/molmil-images/mine/8hjv) | Cryo-EM structure of carotenoid-depleted RC-LH complex from Roseiflexus castenholzii at 10,000 lux | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-methyl-3-[(2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione, Alpha subunit of light-harvesting 1, ... | 著者 | Xu, X, Xin, J. | 登録日 | 2022-11-23 | 公開日 | 2023-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Carotenoid assembly regulates quinone diffusion and the Roseiflexus castenholzii reaction center-light harvesting complex architecture. Elife, 12, 2023
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8BZ6
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8HJU
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![BU of 8hju by Molmil](/molmil-images/mine/8hju) | Cryo-EM structure of native RC-LH complex from Roseiflexus castenholzii at 10,000 lux | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-methyl-3-[(2E,6E,10E,14E,18E,22E,26E,30E,34E,38E)-3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,1 4,18,22,26,30,34,38,42-undecaen-1-yl]naphthalene-1,4-dione, Alpha subunit of light-harvesting 1, ... | 著者 | Xu, X, Xin, J. | 登録日 | 2022-11-23 | 公開日 | 2023-09-20 | 最終更新日 | 2023-10-04 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Carotenoid assembly regulates quinone diffusion and the Roseiflexus castenholzii reaction center-light harvesting complex architecture. Elife, 12, 2023
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8GZ8
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8BZL
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![BU of 8bzl by Molmil](/molmil-images/mine/8bzl) | Human 20S Proteasome in complex with peptide activator peptide BLM42 | 分子名称: | ARG-SER-TYR-TYR-SER, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Henneberg, F, Chari, A, Jankowska, E, Witkowska, J. | 登録日 | 2022-12-15 | 公開日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Peptidic, Blm10-based activators of human 20S proteasome in vitro and in cellulo enhance degradation of proteins connected with neurodegeneration. To Be Published
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5E7K
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![BU of 5e7k by Molmil](/molmil-images/mine/5e7k) | Structure of T. thermophilus 70S ribosome complex with mRNA and cognate tRNALys in the A-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Demeshkina, N, Khusainov, I, Yusupov, M, Yusupova, G. | 登録日 | 2015-10-12 | 公開日 | 2016-01-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code. Nat Commun, 7, 2016
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1D5M
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![BU of 1d5m by Molmil](/molmil-images/mine/1d5m) | X-RAY CRYSTAL STRUCTURE OF HLA-DR4 COMPLEXED WITH PEPTIDE AND SEB | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENTEROTOXIN TYPE B, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Swain, A.L, Crowther, R, Kammlott, U. | 登録日 | 1999-10-07 | 公開日 | 2000-06-28 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures. J.Med.Chem., 43, 2000
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8HL5
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7R4Q
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![BU of 7r4q by Molmil](/molmil-images/mine/7r4q) | The SARS-CoV-2 spike in complex with the 1.29 neutralizing nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Camel-derived nanobody 1.29, ... | 著者 | Casasnovas, J.M, Melero, R, Arranz, R, Fernandez, L.A. | 登録日 | 2022-02-09 | 公開日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron. Front Immunol, 13, 2022
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8HL3
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6OB0
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![BU of 6ob0 by Molmil](/molmil-images/mine/6ob0) | Compound 2 bound structure of WT Lipoprotein Lipase in Complex with GPIHBP1 Mutant N78D N82D produced in HEK293-F cells | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Arora, R, Horton, P.A, Benson, T.E, Romanowski, M.J. | 登録日 | 2019-03-19 | 公開日 | 2019-05-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structure of lipoprotein lipase in complex with GPIHBP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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7R4I
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![BU of 7r4i by Molmil](/molmil-images/mine/7r4i) | The SARS-CoV-2 spike in complex with the 2.15 neutralizing nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Camel-derived nanobody 2.15, ... | 著者 | Casasnovas, J.M, Melero, R, Arranz, R, Fernandez, L.A. | 登録日 | 2022-02-08 | 公開日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron. Front Immunol, 13, 2022
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8TJ6
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![BU of 8tj6 by Molmil](/molmil-images/mine/8tj6) | CRYSTAL STRUCTURE OF THE A/Beijing/353/1989(H3N2) INFLUENZA VIRUS HEMAGGLUTININ WITH HUMAN RECEPTOR ANALOG 6'-SLN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wu, N.C, Zhu, X, Wilson, I.A. | 登録日 | 2023-07-20 | 公開日 | 2024-02-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host Microbe, 32, 2024
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7R5K
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![BU of 7r5k by Molmil](/molmil-images/mine/7r5k) | Human nuclear pore complex (constricted) | 分子名称: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | 著者 | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | 登録日 | 2022-02-10 | 公開日 | 2022-06-22 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (12 Å) | 主引用文献 | AI-based structure prediction empowers integrative structural analysis of human nuclear pores. Science, 376, 2022
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7RSZ
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![BU of 7rsz by Molmil](/molmil-images/mine/7rsz) | HIV-1 gp120 complex with CJF-II-204 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 gp120 Clade C1086, N~1~-{(1R,2R,3S)-2-(carbamimidamidomethyl)-3-[(3R)-3,4-dihydroxybutyl]-5-[(methylamino)methyl]-2,3-dihydro-1H-inden-1-yl}-N~2~-(4-chloro-3-fluorophenyl)ethanediamide, ... | 著者 | Liang, S, Hendrickson, W.A. | 登録日 | 2021-08-12 | 公開日 | 2022-06-08 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Identification of gp120 Residue His105 as a Novel Target for HIV-1 Neutralization by Small-Molecule CD4-Mimics. Acs Med.Chem.Lett., 12, 2021
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8CVL
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![BU of 8cvl by Molmil](/molmil-images/mine/8cvl) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, aminoacylated A-site Phe-NH-tRNAphe, peptidyl P-site fMTHSMRC-NH-tRNAmet, and deacylated E-site tRNAphe at 2.30A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Syroegin, E.A, Aleksandrova, E.V, Polikanov, Y.S. | 登録日 | 2022-05-18 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Insights into the ribosome function from the structures of non-arrested ribosome-nascent chain complexes. Nat.Chem., 15, 2023
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7R4R
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![BU of 7r4r by Molmil](/molmil-images/mine/7r4r) | The SARS-CoV-2 spike in complex with the 1.10 neutralizing nanobody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Camel-derived nanobody 1.10, ... | 著者 | Casasnovas, J.M, Melero, R, Arranz, R, Fernandez, L.A. | 登録日 | 2022-02-09 | 公開日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Nanobodies Protecting From Lethal SARS-CoV-2 Infection Target Receptor Binding Epitopes Preserved in Virus Variants Other Than Omicron. Front Immunol, 13, 2022
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6O9J
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![BU of 6o9j by Molmil](/molmil-images/mine/6o9j) | 70S Elongation Competent Ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Frank, J, Gonzalez Jr, R.L, Kaledhonkar, S, Fu, Z, Caban, K, Li, W, Chen, B, Sun, M. | 登録日 | 2019-03-14 | 公開日 | 2019-05-29 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Late steps in bacterial translation initiation visualized using time-resolved cryo-EM. Nature, 570, 2019
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5DM7
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![BU of 5dm7 by Molmil](/molmil-images/mine/5dm7) | Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with hygromycin A | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... | 著者 | Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P. | 登録日 | 2015-09-08 | 公開日 | 2015-11-11 | 最終更新日 | 2015-11-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A. Nucleic Acids Res., 43, 2015
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7R0R
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