PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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6UFN	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 7-[(3-aminopropyl)amino]heptan-2-one 分子名称: 7-[(3-aminopropyl)amino]heptane-2,2-diol, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-09-24 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
6UHV	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 6-[(3-aminopropyl)amino]-N-hydroxyhexanamide 分子名称: 6-[(3-aminopropyl)amino]-N-hydroxyhexanamide, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-09-28 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.53 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
6UII	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 5-[(3-aminopropyl)amino]pentane-1-thiol 分子名称: 5-[(3-aminopropyl)amino]pentane-1-thiol, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-10-01 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
6TXW	V30G Transthyretin structure in complex with Tolcalpone 分子名称: Tolcapone, Transthyretin 著者 Varejao, N, Reverter, D, Pinheiro, F, Pallares, I, Ventura, S. 登録日 2020-01-14 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.153 Å) 主引用文献 Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis. Febs J., 288, 2021
4BSZ	Crystal Structure of the Yeast Ribosomal Protein Rps3 in Complex with its Chaperone Yar1 分子名称: 40S RIBOSOMAL PROTEIN S3, ANKYRIN REPEAT-CONTAINING PROTEIN YAR1 著者 Holzer, S, Ban, N, Klinge, S. 登録日 2013-06-12 公開日 2013-09-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.842 Å) 主引用文献 Crystal Structure of the Yeast Ribosomal Protein Rps3 in Complex with its Chaperone Yar1 J.Mol.Biol., 425, 2013
6TXV	A25T Transthyretin structure in complex with Tolcalpone 分子名称: Tolcapone, Transthyretin 著者 Varejao, N, Reverter, D, Pinheiro, F, Pallares, I, Ventura, S. 登録日 2020-01-14 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis. Febs J., 288, 2021
5MTD	Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form II 分子名称: NICKEL (II) ION, Putative uncharacterized protein orf60T, TRIETHYLENE GLYCOL, ... 著者 Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. 登録日 2017-01-09 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
6UIM	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 7-{[(3-aminopropyl)amino]-2-oxoheptyl} thioacetate 分子名称: 7-[(3-aminopropyl)amino]-1-sulfanylheptan-2-one, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-10-01 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
5MTC	Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form I 分子名称: NICKEL (II) ION, Putative uncharacterized protein orf60T, ZINC ION 著者 Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. 登録日 2017-01-09 公開日 2017-09-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
6U1R	SxtG an amidinotransferase from the Microseira wollei in Saxitoxin biosynthetic pathway 分子名称: FORMIC ACID, SxtG 著者 Mallik, L, Lukowski, A.L, Narayan, A.R.H, Koutmos, M. 登録日 2019-08-16 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.792 Å) 主引用文献 Substrate Promiscuity of a Paralytic Shellfish Toxin Amidinotransferase. Acs Chem.Biol., 15, 2020
7Y2P	Crystal structure of CUG repeat RNA duplex containing A-U base pair and U-U mismatches 分子名称: RNA (5'-R(P*UP*UP*CP*UP*GP*CP*AP*GP*CP*UP*GP*AP*A)-3'), RNA (5'-R(P*UP*UP*CP*UP*GP*CP*UP*GP*CP*UP*GP*AP*A)-3') 著者 Wang, S.C, Satange, R.B, Hou, M.H. 登録日 2022-06-09 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1. J.Biol.Chem., 299, 2023
7Y2B	Crystal structure of CUG repeat RNA duplex containing U-U mismatches 分子名称: RNA (5'-R(P*UP*UP*CP*UP*GP*CP*UP*GP*CP*UP*GP*AP*A)-3') 著者 Wang, S.C, Satange, R.B, Hou, M.H. 登録日 2022-06-09 公開日 2023-05-31 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Structural basis for water modulating RNA duplex formation in the CUG repeats of myotonic dystrophy type 1. J.Biol.Chem., 299, 2023
6UIJ	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with S-{5-[(3-aminopropyl)amino]pentyl} thioacetate 分子名称: 5-[(3-aminopropyl)amino]pentane-1-thiol, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-10-01 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
6UHU	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 5-[(3-aminopropyl)amino]pentylboronic acid 分子名称: 5-(3-azanylpropylamino)pentyl-$l^{3}-oxidanyl-bis(oxidanyl)boron, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-09-28 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
6UFO	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 7-[(3-aminopropyl)amino]-1-methoxyheptan-2-one 分子名称: 7-[(3-aminopropyl)amino]-1-methoxyheptane-2,2-diol, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-09-24 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
6UIL	Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 7-[(3-aminopropyl)amino]-1,1,1-trifluoroheptan-2-one 分子名称: 7-[(3-aminopropyl)amino]-1,1,1-trifluoroheptane-2,2-diol, PHOSPHATE ION, POTASSIUM ION, ... 著者 Herbst-Gervasoni, C.J, Christianson, D.W. 登録日 2019-10-01 公開日 2019-12-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58, 2019
6EUQ	MdfA(Q131R/L339E) 分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, ACETATE ION, HEXANE, ... 著者 Tam, H.K, Zomot, E, Bibi, E, Pos, K.M. 登録日 2017-10-31 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter. J. Mol. Biol., 430, 2018
7VRE	The crystal structure of EGFR T790M/C797S with the inhibitor HCD2892 分子名称: 5-chloranyl-N-[5-chloranyl-2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-(1-ethylsulfonylindol-3-yl)pyrimidin-2-amine, Epidermal growth factor receptor 著者 Zhu, S.J. 登録日 2021-10-22 公開日 2022-06-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.507 Å) 主引用文献 Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022
7VRA	The crystal structure of EGFR T790M/C797S with the inhibitor HC5476 分子名称: 25-chloro-11-(ethylsulfonyl)-44-morpholino-11H-5,12-dioxa-3-aza-1(3,6)-indola-2(4,2)-pyrimidina-4(1,3)-benzenacyclododecaphane, Epidermal growth factor receptor 著者 Zhu, S.J. 登録日 2021-10-22 公開日 2022-06-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations. J.Med.Chem., 65, 2022
6V8O	RSC core 分子名称: Chromatin structure-remodeling complex protein RSC14, Chromatin structure-remodeling complex protein RSC3, Chromatin structure-remodeling complex protein RSC30, ... 著者 Patel, A.B, Moore, C.M, Greber, B.J, Nogales, E. 登録日 2019-12-11 公開日 2020-01-15 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement. Elife, 8, 2019
6DD5	Crystal Structure of the Cas6 Domain of Marinomonas mediterranea MMB-1 Cas6-RT-Cas1 Fusion Protein 分子名称: GLYCEROL, MMB-1 Cas6 Fused to Maltose Binding Protein,CRISPR-associated endonuclease Cas1, SULFATE ION, ... 著者 Stamos, J.L, Mohr, G, Silas, S, Makarova, K.S, Markham, L.M, Yao, J, Lucas-Elio, P, Sanchez-Amat, A, Fire, A.Z, Koonin, E.V, Lambowitz, A.M. 登録日 2018-05-09 公開日 2018-10-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 A Reverse Transcriptase-Cas1 Fusion Protein Contains a Cas6 Domain Required for Both CRISPR RNA Biogenesis and RNA Spacer Acquisition. Mol. Cell, 72, 2018
6DHT	Bacteroides ovatus GH9 Bacova_02649 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Koropatkin, N.M, Foley, M.H. 登録日 2018-05-21 公開日 2019-04-03 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 A Cell-Surface GH9 Endo-Glucanase Coordinates with Surface Glycan-Binding Proteins to Mediate Xyloglucan Uptake in the Gut Symbiont Bacteroides ovatus. J. Mol. Biol., 431, 2019
1YZ6	Crystal structure of intact alpha subunit of aIF2 from Pyrococcus abyssi 分子名称: Probable translation initiation factor 2 alpha subunit 著者 Yatime, L, Schmitt, E, Blanquet, S, Mechulam, Y. 登録日 2005-02-28 公開日 2005-06-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.37 Å) 主引用文献 Structure-Function Relationships of the Intact aIF2alpha Subunit from the Archaeon Pyrococcus abyssi Biochemistry, 44, 2005
5O56	Glycogen Phosphorylase b in complex with 29b 分子名称: (2~{R},3~{S},4~{R},5~{R},6~{R})-5-azanyl-2-(hydroxymethyl)-6-(3-naphthalen-2-yl-1~{H}-1,2,4-triazol-5-yl)oxane-3,4-diol, Glycogen phosphorylase, muscle form, ... 著者 Solovou, T.G.A, Kyriakis, E, Stravodimos, G.A, Kantsadi, A.L, Chatzileontiadou, D.S, Skamnaki, V.T, Leonidas, D.D. 登録日 2017-05-31 公開日 2017-09-27 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Nanomolar Inhibitors of Glycogen Phosphorylase Based on beta-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study. J. Med. Chem., 60, 2017
5OCC	Crystal structure of CD32b (Fc Gamma Receptor IIb) in complex with Human IgG1 Fab fragment (6G08) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6G08 Fab Light Chain, ... 著者 Tews, I, Orr, C. 登録日 2017-06-30 公開日 2018-07-25 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Evaluating Anti-CD32b F(ab) Conformation Using Molecular Dynamics and Small-Angle X-Ray Scattering. Biophys. J., 115, 2018

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