6UFO

Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 7-[(3-aminopropyl)amino]-1-methoxyheptan-2-one

Summary for 6UFO

Entry DOI	10.2210/pdb6ufo/pdb
Descriptor	Polyamine deacetylase HDAC10, 7-[(3-aminopropyl)amino]-1-methoxyheptane-2,2-diol, ZINC ION, ... (6 entities in total)
Functional Keywords	histone deacetylase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Danio rerio (Zebrafish)
Total number of polymer chains	1
Total formula weight	75704.46
Authors	Herbst-Gervasoni, C.J.,Christianson, D.W. (deposition date: 2019-09-24, release date: 2019-12-04, Last modification date: 2023-10-11)
Primary citation	Herbst-Gervasoni, C.J.,Christianson, D.W. Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58:4957-4969, 2019 Cited by PubMed: 31746596 DOI: 10.1021/acs.biochem.9b00906 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.68 Å)

Structure validation