6UHV

Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with 6-[(3-aminopropyl)amino]-N-hydroxyhexanamide

Summary for 6UHV

Entry DOI	10.2210/pdb6uhv/pdb
Descriptor	Polyamine deacetylase HDAC10, 6-[(3-aminopropyl)amino]-N-hydroxyhexanamide, ZINC ION, ... (6 entities in total)
Functional Keywords	histone deacetylase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Danio rerio
Total number of polymer chains	1
Total formula weight	75578.44
Authors	Herbst-Gervasoni, C.J.,Christianson, D.W. (deposition date: 2019-09-28, release date: 2019-12-04, Last modification date: 2023-10-11)
Primary citation	Herbst-Gervasoni, C.J.,Christianson, D.W. Binding ofN8-Acetylspermidine Analogues to Histone Deacetylase 10 Reveals Molecular Strategies for Blocking Polyamine Deacetylation. Biochemistry, 58:4957-4969, 2019 Cited by PubMed: 31746596 DOI: 10.1021/acs.biochem.9b00906 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.53 Å)

Structure validation