PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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3GY5	A comparative study on the inhibition of bovine beta-trypsin by bis-benzamidines diminazene and pentamidine by X-ray crystallography and ITC 分子名称: 1,2-ETHANEDIOL, BERENIL, CALCIUM ION, ... 著者 Perilo, C.S, Pereira, M.T, Santoro, M.M, Nagem, R.A.P. 登録日 2009-04-03 公開日 2010-03-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Structural binding evidence of the trypanocidal drugs Berenil and Pentacarinate active principles to a serine protease model. Int.J.Biol.Macromol., 46, 2010
3GY4	A comparative study on the inhibition of bovine beta-trypsin by bis-benzamidines diminazene and pentamidine by X-ray crystallography and ITC 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... 著者 Perilo, C.S, Pereira, M.T, Santoro, M.M, Nagem, R.A.P. 登録日 2009-04-03 公開日 2010-03-23 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Structural binding evidence of the trypanocidal drugs Berenil and Pentacarinate active principles to a serine protease model. Int.J.Biol.Macromol., 46, 2010
1HZ3	ALZHEIMER'S DISEASE AMYLOID-BETA PEPTIDE (RESIDUES 10-35) 分子名称: A-BETA AMYLOID 著者 Zhang, S, Iwata, K, Lachenmann, M.J, Peng, J.W, Li, S, Stimson, E.R, Lu, Y, Felix, A.M, Maggio, J.E, Lee, J.P. 登録日 2001-01-23 公開日 2001-01-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The Alzheimer's peptide a beta adopts a collapsed coil structure in water. J.Struct.Biol., 130, 2000
3W20	Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD 分子名称: Putative uncharacterized protein, ZINC ION 著者 Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. 登録日 2012-11-26 公開日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD Plos One, 8, 2013
3W21	Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase in complex with alpha-KG from Burkholderia ambifaria AMMD 分子名称: 2-OXOGLUTARIC ACID, Putative uncharacterized protein, ZINC ION 著者 Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. 登録日 2012-11-26 公開日 2013-07-17 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD Plos One, 8, 2013
1IXI	PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 56 REPLACED BY ASN COMPLEX WITH MONOBASIC PHOSPHATE ION 分子名称: DIHYDROGENPHOSPHATE ION, PHOSPHATE-BINDING PROTEIN 著者 Wang, Z, Quiocho, F.A. 登録日 1996-10-17 公開日 1997-10-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes. Nat.Struct.Biol., 4, 1997
1IXG	PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE 分子名称: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN 著者 Wang, Z, Luecke, H, Quiocho, F.A. 登録日 1996-08-01 公開日 1998-02-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes. Nat.Struct.Biol., 4, 1997
1IXH	PHOSPHATE-BINDING PROTEIN (PBP) COMPLEXED WITH PHOSPHATE 分子名称: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN 著者 Wang, Z, Luecke, H, Quiocho, F.A. 登録日 1996-08-01 公開日 1998-02-04 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes. Nat.Struct.Biol., 4, 1997
2XRU	AURORA-A T288E COMPLEXED WITH PHA-828300 分子名称: 3-({[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]CARBONYL}AMINO)-N-[(1R)-1-PHENYLPROPYL]-1H-THIENO[3,2-C]PYRAZOLE-5-CARBOXAMIDE, SERINE/THREONINE-PROTEIN KINASE 6 著者 Bindi, S, Fancelli, D, Alli, C, Berta, D, Bertrand, J.A, Cameron, A.D, Cappella, P, Carpinelli, P, Cervi, G, Croci, W, D'Anello, M, Forte, B, LauraGiorgini, M, Marsiglio, A, Moll, J, Pesenti, E, Pittala, V, Pulici, M, Riccardi-Sirtori, F, Roletto, F, Soncini, C, Storici, P, Varasi, M, Volpi, D, Zugnoni, P, Vianello, P. 登録日 2010-09-22 公開日 2010-09-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Thieno[3,2-C]Pyrazoles: A Novel Class of Aurora Inhibitors with Favorable Antitumor Activity. Bioorg.Med.Chem., 18, 2010
3MLG	2ouf-2x, a designed knotted protein 分子名称: 2X chimera of Helicobacter pylori protein HP0242 著者 King, N.P, Sawaya, M.R, Jacobitz, A.W, Yeates, T.O. 登録日 2010-04-16 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Structure and folding of a designed knotted protein. Proc.Natl.Acad.Sci.USA, 107, 2010
1VZK	A Thiophene Based Diamidine Forms a "Super" AT Binding Minor Groove Agent 分子名称: 2-(5-{4-[AMINO(IMINO)METHYL]PHENYL}-2-THIENYL)-1H-BENZIMIDAZOLE-6- CARBOXIMIDAMIDE DIHYDROCHLORIDE, 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP *CP*G)-3', MAGNESIUM ION 著者 Mallena, S, Lee, M.P.H, Bailly, C, Neidle, S, Kumar, A, Boykin, D.W, Wilson, W.D. 登録日 2004-05-20 公開日 2004-10-25 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Thiophene-Based Diamidine Forms a "Super" at Binding Minor Groove Agent J.Am.Chem.Soc., 142, 2004
1NDE	Estrogen Receptor beta with Selective Triazine Modulator 分子名称: 4-(2-{[4-{[3-(4-CHLOROPHENYL)PROPYL]SULFANYL}-6-(1-PIPERAZINYL)-1,3,5-TRIAZIN-2-YL]AMINO}ETHYL)PHENOL, Estrogen receptor beta 著者 Henke, B.R, Consler, T.G, Go, N, Hale, R.L, Hohman, D.R, Jones, S.A, Lu, A.T, Moore, L.B, Moore, J.T, Orband-Miller, L.A, Robinett, R.G, Shearin, J, Spearing, P.K, Stewart, E.L, Turnbull, P.S, Weaver, S.L, Williams, S.P, Wisely, G.B, Lambert, M.H. 登録日 2002-12-09 公開日 2002-12-18 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A New Series of Estrogen Receptor Modulators That Display Selectivity for Estrogen Receptor beta J.Med.Chem., 45, 2002
5O33	A structure of the GEF Kalirin DH1 domain in complex with the small GTPase Rac1 分子名称: 1,2-ETHANEDIOL, GUANOSINE-5'-DIPHOSPHATE, Kalirin, ... 著者 Gray, J, Krojer, T, Talon, R, Fairhead, M, Bountra, C, Arrowsmith, C.H, Edwards, A, Brennan, P, von Delft, F. 登録日 2017-05-23 公開日 2017-05-31 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 A structure of the GEF Kalirin DH1 domain in complex with the small GTPase Rac1 To Be Published
3CXU	Structure of a Y149F mutant of epoxide hydrolase from Solanum tuberosum 分子名称: Epoxide hydrolase, TETRAETHYLENE GLYCOL 著者 Naworyta, A, Mowbray, S.L, Widersten, M, Thomaeus, A. 登録日 2008-04-25 公開日 2008-07-08 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability Protein Sci., 17, 2008
3MLI	2ouf-ds, a disulfide-linked dimer of Helicobacter pylori protein HP0242 分子名称: CALCIUM ION, Putative uncharacterized protein 著者 King, N.P, Sawaya, M.R, Jacobitz, A.W, Yeates, T.O. 登録日 2010-04-16 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure and folding of a designed knotted protein. Proc.Natl.Acad.Sci.USA, 107, 2010
4J2K	Crystal structure of a plant trypsin inhibitor EcTI 分子名称: GLYCEROL, IMIDAZOLE, Trypsin inhibitor 著者 Zhou, D, Wlodawer, A. 登録日 2013-02-04 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal Structures of a Plant Trypsin Inhibitor from Enterolobium contortisiliquum (EcTI) and of Its Complex with Bovine Trypsin. Plos One, 8, 2013
4FYN	Crystal structure of spleen tyrosine kinase complexed with 3-(8-{4-[Ethyl-(2-hydroxy-ethyl)-amino]-phenylamino}-imidazo[1,2-a]pyrazin-5-yl)-phenol 分子名称: 3-[8-({4-[ethyl(2-hydroxyethyl)amino]phenyl}amino)imidazo[1,2-a]pyrazin-5-yl]phenol, Tyrosine-protein kinase SYK 著者 Kuglstatter, A, Villasenor, A.G. 登録日 2012-07-05 公開日 2013-01-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.318 Å) 主引用文献 Rational design of highly selective spleen tyrosine kinase inhibitors. J.Med.Chem., 55, 2012
1KXM	Crystal structure of Cytochrome c Peroxidase with a Proposed Electron Transfer Pathway Excised to Form a Ligand Binding Channel. 分子名称: BENZIMIDAZOLE, Cytochrome c Peroxidase, PROTOPORPHYRIN IX CONTAINING FE 著者 Rosenfeld, R.J, Hayes, A.M.A, Musah, R.A, Goodin, D.B. 登録日 2002-02-01 公開日 2002-03-06 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Excision of a proposed electron transfer pathway in cytochrome c peroxidase and its replacement by a ligand-binding channel. Protein Sci., 11, 2002
4KC4	Structure of the blood group glycosyltransferase AAglyB in complex with a pyridine inhibitor as a neutral pyrophosphate surrogate 分子名称: 5'-deoxy-5'-[({6-[(alpha-D-galactopyranosyloxy)methyl]pyridin-2-yl}carbonyl)amino]uridine, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, MANGANESE (II) ION, ... 著者 Cuesta-Seijo, J.A, Wang, S, Lafont, D, Vidal, S, Palcic, M.M. 登録日 2013-04-24 公開日 2013-09-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Design of glycosyltransferase inhibitors: pyridine as a pyrophosphate surrogate. Chemistry, 19, 2013
1JJP	A(GGGG) Pentad-Containing Dimeric DNA Quadruplex Involving Stacked G(anti)G(anti)G(anti)G(syn) Tetrads 分子名称: 5'-D(*GP*GP*GP*AP*GP*GP*TP*TP*TP*GP*GP*GP*AP*T)-3' 著者 Zhang, N, Gorin, A, Majumdar, A, Kettani, A, Chernichenko, N, Skripkin, E, Patel, D.J. 登録日 2001-07-09 公開日 2001-09-19 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads. J.Mol.Biol., 311, 2001
4GX9	Crystal structure of a DNA polymerase III alpha-epsilon chimera 分子名称: DNA polymerase III subunit epsilon,DNA polymerase III subunit alpha 著者 Li, N, Horan, N, Xu, Z.-Q, Jacques, D, Dixon, N.E, Oakley, A.J. 登録日 2012-09-04 公開日 2013-04-03 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits alpha, {varepsilon}, theta and beta reveals a highly flexible arrangement of the proofreading domain Nucleic Acids Res., 41, 2013
4J2Y	Crystal structure of a plant trypsin inhibitor EcTI in complex with bovine trypsin. 分子名称: Cationic trypsin, SULFATE ION, Trypsin inhibitor 著者 Zhou, D, Wlodawer, A. 登録日 2013-02-05 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structures of a Plant Trypsin Inhibitor from Enterolobium contortisiliquum (EcTI) and of Its Complex with Bovine Trypsin. Plos One, 8, 2013
1KXN	Crystal Structure of Cytochrome c Peroxidase with a Proposed Electron Transfer Pathway Excised to Form a Ligand Binding Channel. 分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome c peroxidase 著者 Rosenfeld, R.J, Hayes, A.M.A, Musah, R.A, Goodin, D.B. 登録日 2002-02-01 公開日 2002-03-06 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Excision of a proposed electron transfer pathway in cytochrome c peroxidase and its replacement by a ligand-binding channel. Protein Sci., 11, 2002
4DK5	Crystal structure of human PI3K-gamma in complex with a pyridyl-triazine inhibitor 分子名称: 4-(2-[(6-methoxypyridin-3-yl)amino]-5-{[4-(methylsulfonyl)piperazin-1-yl]methyl}pyridin-3-yl)-6-methyl-1,3,5-triazin-2-amine, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION 著者 Whittington, D.A, Tang, J, Yakowec, P. 登録日 2012-02-03 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases. J.Med.Chem., 55, 2012
1MD3	A folding mutant of human class pi glutathione transferase, created by mutating glycine 146 of the wild-type protein to alanine 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, pi glutathione transferase 著者 Kong, G.K.-W, Dragani, B, Aceto, A, Cocco, R, Mannervik, B, Stenberg, G, McKinstry, W.J, Polekhina, G, Parker, M.W. 登録日 2002-08-06 公開日 2002-08-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Contribution of Glycine 146 to a Conserved Folding Module Affecting Stability and Refolding of Human Glutathione Transferase P1-1 J.Biol.Chem., 278, 2003

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