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2QQB
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Crystal Structure of DtxR(M10A C102D) Complexed with Nickel(II)
分子名称: Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION
著者D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D.
登録日2007-07-26
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
2QQA
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Crystal Structure of DtxR(E9A C102D) Complexed with Nickel(II)
分子名称: Diphtheria toxin repressor, NICKEL (II) ION, PHOSPHATE ION
著者D'Aquino, J.A, Lattimer, J.R, Denninger, A, D'Aquino, K.E, Ringe, D.
登録日2007-07-26
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Role of the N-Terminal Helix in the Metal Ion-Induced Activation of the Diphtheria Toxin Repressor DtxR.
Biochemistry, 46, 2007
2P1Q
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Mechanism of Auxin Perception by the TIR1 ubiquitin ligase
分子名称: 1H-INDOL-3-YLACETIC ACID, Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, ...
著者Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N.
登録日2007-03-06
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Mechanism of auxin perception by the TIR1 ubiquitin ligase.
Nature, 446, 2007
6UVU
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BU of 6uvu by Molmil
Crystal structure of the AntR antimony-specific transcriptional repressor
分子名称: ArsR family transcriptional regulator
著者Thiruselvam, V, Banumathi, S, Palani, K, Manohar, R, Rosen, B.P.
登録日2019-11-04
公開日2020-11-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Functional and structural characterization of AntR, an Sb(III) responsive transcriptional repressor.
Mol.Microbiol., 116, 2021
6FAL
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Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid as ligand
分子名称: INDOLYLPROPIONIC ACID, Trp operon repressor
著者Stiel, A.C, Shanmugaratnam, S, Hocker, B.
登録日2017-12-15
公開日2019-01-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Tryptophan Repressor TrpR from E.coli: A ligand binding study
To Be Published
6F7F
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Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid
分子名称: INDOLYLPROPIONIC ACID, Trp operon repressor
著者Stiel, A.C, Shanmugaratnam, S, Hocker, B.
登録日2017-12-08
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.128 Å)
主引用文献Tryptophan Repressor TrpR: A study of ligand binding specificity
To Be Published
6F7G
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Tryptophan Repressor TrpR from E.coli with 5-Methyltryptamine
分子名称: 2-(5-methyl-1~{H}-indol-3-yl)ethanamine, Trp operon repressor
著者Stiel, A.C, Shanmugaratnam, S, Hocker, B.
登録日2017-12-08
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.656 Å)
主引用文献Tryptophan Repressor TrpR: A ligand specificity study
To Be Published
6F9K
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BU of 6f9k by Molmil
Tryptophan Repressor TrpR from E.coli with 5-methyl-L-tryptophan as ligand
分子名称: 5-methyl-L-tryptophan, SULFATE ION, Trp operon repressor
著者Stiel, A.C, Shanmugaratnam, S, Hocker, B.
登録日2017-12-14
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.399 Å)
主引用文献Tryptophan Repressor TrpR from E.coli: A ligand binding study
To Be Published
5JLU
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Crystal Structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes
分子名称: Adhesin competence repressor, ZINC ION
著者Do, H, Kumaraswami, M.
登録日2016-04-27
公開日2017-05-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Adhesin competence repressor (AdcR) from Streptococcus pyogenes
To Be Published
6WMQ
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Crystal Structure of Human REV-ERBbeta Ligand Binding Domain Co-Bound to Heme and NCoR ID1 Peptide
分子名称: Nuclear receptor Rev-ErbA beta variant 1, Nuclear receptor corepressor 1, PROTOPORPHYRIN IX CONTAINING FE
著者Mosure, S.A, Shang, J, Kojetin, D.J.
登録日2020-04-21
公開日2021-02-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERB beta.
Sci Adv, 7, 2021
3N00
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BU of 3n00 by Molmil
Crystal Structure of a deletion mutant of human Reverba ligand binding domain bound with an NCoR ID1 peptide determined to 2.60A
分子名称: Nuclear receptor corepressor 1, Rev-erbA-alpha
著者Gampe, R, Nolte, R.
登録日2010-05-13
公開日2010-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Rev-erbalpha bound to N-CoR reveals a unique mechanism of nuclear receptor-co-repressor interaction.
Nat.Struct.Mol.Biol., 17, 2010
1UI5
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BU of 1ui5 by Molmil
Crystal structure of gamma-butyrolactone receptor (ArpA like protein)
分子名称: A-factor receptor homolog
著者Natsume, R, Senda, T, Horinouchi, S.
登録日2003-07-15
公開日2004-07-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a gamma-butyrolactone autoregulator receptor protein in Streptomyces coelicolor A3(2)
J.Mol.Biol., 336, 2004
3MI7
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BU of 3mi7 by Molmil
An Enhanced Repressor of Human Papillomavirus E2 Protein
分子名称: 1,2-ETHANEDIOL, Regulatory protein E2
著者Bohm, A, Baleja, J, Bose, K, Meinke, G.
登録日2010-04-09
公開日2011-04-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design and characterization of an enhanced repressor of human papillomavirus E2 protein.
Faseb J., 25, 2011
6CBQ
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BU of 6cbq by Molmil
Crystal structure of QscR bound to agonist S3
分子名称: (2S)-2-hexyl-N-[(3S)-2-oxooxolan-3-yl]decanamide, LuxR family transcriptional regulator
著者Churchill, M.E.A, Wysoczynski-Horita, C.L.
登録日2018-02-05
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of agonism and antagonism of the Pseudomonas aeruginosa quorum sensing regulator QscR with non-native ligands.
Mol. Microbiol., 108, 2018
6RNX
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BU of 6rnx by Molmil
Crystal structure of the essential repressor DdrO from radiation-resistant Deinococcus bacteria (Deinococcus deserti)
分子名称: CHLORIDE ION, HTH-type transcriptional regulator DdrOC
著者Arnoux, P, Siponen, M.I, Pignol, D, De Groot, A, Blanchard, L.
登録日2019-05-09
公開日2019-10-09
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus.
Nucleic Acids Res., 47, 2019
6C9T
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BU of 6c9t by Molmil
Transcriptional repressor, CouR
分子名称: CouR
著者Cogan, D.P, Nair, S.K.
登録日2018-01-28
公開日2018-05-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, inRhodopseudomonas palustris.
J. Biol. Chem., 293, 2018
6C28
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BU of 6c28 by Molmil
Transcriptional repressor, CouR, bound to p-coumaroyl-CoA
分子名称: Transcriptional regulator, MarR family, p-coumaroyl-CoA
著者Cogan, D.P, Nair, S.K.
登録日2018-01-07
公開日2018-05-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural basis of transcriptional regulation by CouR, a repressor of coumarate catabolism, inRhodopseudomonas palustris.
J. Biol. Chem., 293, 2018
5CW8
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BU of 5cw8 by Molmil
Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-4-cholesten-26-oyl-CoA
分子名称: HTH-type transcriptional repressor KstR, S-{1-[5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,7-dihydroxy-6,6-dimethyl-3-oxido-8,12 -dioxo-2,4-dioxa-9,13-diaza-3lambda~5~-phosphapentadecan-15-yl} (2S,6R)-6-[(8S,9S,10R,13R,14S,17R)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta [a]phenanthren-17-yl]-2-methylheptanethioate (non-preferred name), TRIETHYLENE GLYCOL
著者Ho, N.A.T, Dawes, S, Kendall, S, Casabon, I, Crowe, A.M, Baker, E.N, Eltis, L.D, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-07-27
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
5CXG
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BU of 5cxg by Molmil
Crystal structure of Mycobacterium tuberculosis KstR in complex with PEG
分子名称: DI(HYDROXYETHYL)ETHER, HTH-type transcriptional repressor KstR, TRIETHYLENE GLYCOL
著者Ho, N.A.T, Dawes, S, Kendall, S, Baker, E.N, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-07-28
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1001 Å)
主引用文献The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
6RGX
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TETR(D) N82A MUTANT IN COMPLEX WITH DOXYCYCLINE AND MAGNESIUM
分子名称: (4S,4AR,5S,5AR,6R,12AS)-4-(DIMETHYLAMINO)-3,5,10,12,12A-PENTAHYDROXY-6-METHYL-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE, CHLORIDE ION, MAGNESIUM ION, ...
著者Hinrichs, W, Palm, G.J, Berndt, L, Girbardt, B.
登録日2019-04-17
公開日2019-08-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
Biochim Biophys Acta Proteins Proteom, 1868, 2020
1SAX
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BU of 1sax by Molmil
Three-dimensional structure of s.aureus methicillin-resistance regulating transcriptional repressor meci in complex with 25-bp ds-DNA
分子名称: 5'-d(CAAAATTACAACTGTAATATCGGAG)-3', 5'-d(GCTCCGATATTACAGTTGTAATTTT)-3', Methicillin resistance regulatory protein mecI, ...
著者Garcia-Castellanos, R, Mallorqui-Fernandez, G, Marrero, A, Potempa, J, Coll, M, Gomis-Ruth, F.X.
登録日2004-02-09
公開日2004-04-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献On the transcriptional regulation of methicillin resistance: MecI repressor in complex with its operator
J.Biol.Chem., 279, 2004
5CXI
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Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA (4-BNC-CoA)
分子名称: 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA, HTH-type transcriptional repressor KstR
著者Ho, N.A.T, Dawes, S, Kendall, S, Casabon, I, Crowe, A.M, Baker, E.N, Eltis, L.D, Lott, J.S, TB Structural Genomics Consortium (TBSGC)
登録日2015-07-29
公開日2016-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
5D4S
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Crystal Structure of AraR(DBD) in complex with operator ORX1
分子名称: Arabinose metabolism transcriptional repressor, DNA (5'-D(*AP*AP*AP*TP*AP*CP*AP*TP*AP*CP*GP*TP*AP*CP*AP*AP*AP*TP*AP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*TP*AP*TP*TP*TP*GP*TP*AP*CP*GP*TP*AP*TP*GP*TP*AP*TP*T)-3')
著者Jain, D, Narayanan, N, Nair, D.T.
登録日2015-08-08
公開日2015-11-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.972 Å)
主引用文献Plasticity in Repressor-DNA Interactions Neutralizes Loss of Symmetry in Bipartite Operators.
J.Biol.Chem., 291, 2016
5D4R
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Crystal Structure of AraR(DBD) in complex with operator ORE1
分子名称: Arabinose metabolism transcriptional repressor, DNA (5'-D(*AP*TP*AP*TP*TP*TP*GP*TP*AP*CP*GP*TP*AP*CP*TP*AP*AP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*TP*AP*GP*TP*AP*CP*GP*TP*AP*CP*AP*AP*AP*TP*A)-3')
著者Jain, D, Narayanan, N, Nair, D.T.
登録日2015-08-08
公開日2015-11-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Plasticity in Repressor-DNA Interactions Neutralizes Loss of Symmetry in Bipartite Operators.
J.Biol.Chem., 291, 2016
5E24
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Structure of the Su(H)-Hairless-DNA Repressor Complex
分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), ...
著者Kovall, R.A, Yuan, Z.
登録日2015-09-30
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Structure and Function of the Su(H)-Hairless Repressor Complex, the Major Antagonist of Notch Signaling in Drosophila melanogaster.
Plos Biol., 14, 2016

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