PDB: 494 件ウェブページステータス検索Chemie searchBIRD

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8H5B	The cryo-EM structure of nuclear transport receptor Kap114p complex with yeast TATA-box binding protein 分子名称: Importin subunit beta-5, TATA-box-binding protein 著者 Hsia, K.C, Liao, C.C, Wang, C.H, Wu, Y.M. 登録日 2022-10-12 公開日 2023-09-20 実験手法 ELECTRON MICROSCOPY (4.03 Å) 主引用文献 Structural convergence endows nuclear transport receptor Kap114p with a transcriptional repressor function toward TATA-binding protein. Nat Commun, 14, 2023
6AHO	Crystal structure of Kap114p 分子名称: Importin subunit beta-5 著者 Liao, C.C, Shankar, S, Ahmed, G.R, Hsia, K.C. 登録日 2018-08-20 公開日 2019-10-23 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.502 Å) 主引用文献 Karyopherin Kap114p-mediated trans-repression controls ribosomal gene expression under saline stress. Embo Rep., 21, 2020
3W3X	Crystal structure of Kap121p bound to Pho4p 分子名称: Importin subunit beta-3, Phosphate system positive regulatory protein PHO4 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
3W3Y	Crystal structure of Kap121p bound to Nup53p 分子名称: Importin subunit beta-3, Nucleoporin NUP53 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
3W3T	Crystal structure of Kap121p 分子名称: Importin subunit beta-3 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
3W3V	Crystal structure of Kap121p mutant D353K/E396K/D438K 分子名称: Importin subunit beta-3 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
3W3W	Crystal structure of Kap121p bound to Ste12p 分子名称: Importin subunit beta-3, Protein STE12 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
3W3U	Crystal structure of Kap121p mutant R349A/Q350A/D353A/E396A/N430K/D438A/N477A 分子名称: Importin subunit beta-3 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
1WA5	Structure of the Cse1:Imp-alpha:RanGTP complex 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin alpha re-exporter, ... 著者 Stewart, M. 登録日 2004-10-23 公開日 2004-12-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the assembly of a nuclear export complex. Nature, 432, 2004
1QBK	STRUCTURE OF THE KARYOPHERIN BETA2-RAN GPPNHP NUCLEAR TRANSPORT COMPLEX 分子名称: KARYOPHERIN BETA2, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Chook, Y.M, Blobel, G. 登録日 1999-04-23 公開日 1999-06-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of the nuclear transport complex karyopherin-beta2-Ran x GppNHp. Nature, 399, 1999
4OL0	Crystal structure of transportin-SR2, a karyopherin involved in human disease, in complex with Ran 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Tsirkone, V.G, Strelkov, S.V. 登録日 2014-01-23 公開日 2014-04-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of transportin SR2, a karyopherin involved in human disease, in complex with Ran. Acta Crystallogr.,Sect.F, 70, 2014
5MFM	Designed armadillo repeat protein peptide fusion YIIIM6AII_GS11_(KR)5 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Importin subunit alpha, ... 著者 Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A. 登録日 2016-11-18 公開日 2017-09-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Curvature of designed armadillo repeat proteins allows modular peptide binding. J. Struct. Biol., 201, 2018
7CYL	Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Chook, Y.M. 登録日 2020-09-03 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X). Sci Rep, 11, 2021
4JLQ	Crystal structure of human Karyopherin-beta2 bound to the PY-NLS of Saccharomyces cerevisiae NAB2 分子名称: Nuclear polyadenylated RNA-binding protein NAB2, Transportin-1 著者 Sampathkumar, P, Gizzi, A, Rout, M.P, Chook, Y.M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Nucleocytoplasmic Transport: a Target for Cellular Control (NPCXstals) 登録日 2013-03-12 公開日 2013-04-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Crystal structure of human Karyopherin beta 2 bound to the PY-NLS of Saccharomyces cerevisiae Nab2. J.Struct.Funct.Genom., 14, 2013
4U2X	Ebola virus VP24 in complex with Karyopherin alpha 5 C-terminus 分子名称: CHLORIDE ION, Importin subunit alpha-6, Membrane-associated protein VP24 著者 Xu, W, Leung, D, Borek, D, Amarasinghe, G. 登録日 2014-07-18 公開日 2014-08-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.153 Å) 主引用文献 Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1. Cell Host Microbe, 16, 2014
7YJI	Crystal structure of Lpg1083 from Legionella pneumophila 分子名称: ACETATE ION, T4SS effector Lpg1083 著者 Ge, H, Gao, J, Chen, X. 登録日 2022-07-20 公開日 2023-06-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The bacterial effector SidN/Lpg1083 promotes cell death by targeting Lamin-B2. J Mol Cell Biol, 15, 2023
2GMO	NMR-structure of an independently folded C-terminal domain of influenza polymerase subunit PB2 分子名称: Polymerase basic protein 2 著者 Boudet, J, Tarendeau, F, Guilligay, D, Mas, P, Bougault, C.M, Cusack, S, Simorre, J.-P, Hart, D.J. 登録日 2006-04-07 公開日 2007-02-27 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit. Nat.Struct.Mol.Biol., 14, 2007
3CH5	The crystal structure of the RanGDP-Nup153ZnF2 complex 分子名称: Fragment of Nuclear pore complex protein Nup153, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Vetter, I.R, Schrader, N. 登録日 2008-03-07 公開日 2008-07-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Crystal Structure of the Ran-Nup153ZnF2 Complex: a General Ran Docking Site at the Nuclear Pore Complex Structure, 16, 2008
1BK6	KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS 分子名称: KARYOPHERIN ALPHA, LARGE T ANTIGEN 著者 Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. 登録日 1998-07-14 公開日 1999-01-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell(Cambridge,Mass.), 94, 1998
1BK5	KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE 分子名称: COBALT (II) ION, KARYOPHERIN ALPHA 著者 Conti, E, Uy, M, Leighton, L, Blobel, G, Kuriyan, J. 登録日 1998-07-14 公開日 1999-01-06 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha. Cell(Cambridge,Mass.), 94, 1998
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5YVH	Crystal structure of Karyopherin beta2 in complex with FUS(371-526) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5YVI	Crystal structure of Karyopherin beta2 in complex with FUS(456-526) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
3W3Z	Crystal structure of Kap121p bound to RanGTP 分子名称: GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, Importin subunit beta-3, ... 著者 Kobayashi, J, Matsuura, Y. 登録日 2012-12-28 公開日 2013-04-10 最終更新日 2014-01-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for cell-cycle-dependent nuclear import mediated by the karyopherin Kap121p. J.Mol.Biol., 425, 2013
8SGH	Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS 分子名称: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed, Transportin-1 著者 Gonzalez, A, Fung, H.Y.J, Chook, Y.M. 登録日 2023-04-12 公開日 2023-06-14 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.17 Å) 主引用文献 A new Karyopherin-beta 2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders. Structure, 31, 2023

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