3VFU
| crystal structure of HLA B*3508 LPEP-P7Ala, peptide mutant P7-ala | 分子名称: | Beta-2-microglobulin, LPEP peptide from EBV, P7A, ... | 著者 | Liu, Y.C, Rossjohn, J, Gras, S. | 登録日 | 2012-01-10 | 公開日 | 2012-02-22 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule. J.Biol.Chem., 287, 2012
|
|
6P2S
| |
2IPU
| |
3FQN
| |
3KLA
| Ca2+ release from the endoplasmic reticulum of NY-ESO-1 specific T cells is modulated by the affinity of T cell receptor and by the use of the CD8 co-receptor | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Chen, J.L, Morgan, A.J, Stewart-Jones, G, Shepherd, D, Bossi, G, Wooldridge, L. | 登録日 | 2009-11-07 | 公開日 | 2010-02-16 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1-Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor. J.Immunol., 184, 2010
|
|
6YTB
| GLYCOSYLATED KNOB/DUMMY-HOLE/DUMMY FC FRAGMENT | 分子名称: | Immunoglobulin gamma-1 heavy chain, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Kuglstatter, A, Leibrock, L, Benz, J. | 登録日 | 2020-04-24 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Format chain exchange (FORCE) for high-throughput generation of bispecific antibodies in combinatorial binder-format matrices. Nat Commun, 11, 2020
|
|
3BH8
| Crystal Structure of RQA_M Phosphopeptide Bound to HUMAN Class I MHC HLA-A2 | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Mohammed, F, Cobbold, M, Zarling, A.L, Salim, M, Barrett-Wilt, G.A, Shabanowitz, J, Hunt, D.F, Engelhard, V.H, Willcox, B.E. | 登録日 | 2007-11-28 | 公開日 | 2008-10-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self Nat.Immunol., 9, 2008
|
|
1L6X
| FC FRAGMENT OF RITUXIMAB BOUND TO A MINIMIZED VERSION OF THE B-DOMAIN FROM PROTEIN A CALLED Z34C | 分子名称: | IMMUNOGLOBULIN GAMMA-1 HEAVY CHAIN CONSTANT REGION, Minimized B-domain of Protein A Z34C, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Idusogie, E.E, Presta, L.G, Santoro-Gazzano, H, Totpal, K, Wong, P.Y, Ultsch, M, Meng, Y.G, Mullkerrin, M.G. | 登録日 | 2002-03-14 | 公開日 | 2002-04-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc. J.Immunol., 164, 2000
|
|
6TDO
| Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GM dipeptide in the A pocket. | 分子名称: | Beta-2-microglobulin, GLYCEROL, GLYCINE, ... | 著者 | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | 登録日 | 2019-11-09 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
|
|
4MD5
| Immune Receptor | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scally, S.W, Rossjohn, J. | 登録日 | 2013-08-22 | 公開日 | 2013-12-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. J.Exp.Med., 210, 2013
|
|
4PRN
| Crystal structure of a HLA-B*35:01-HPVG-A4 | 分子名称: | ACETATE ION, Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, ... | 著者 | Yu Chih, L, Rossjohn, J, Gras, S. | 登録日 | 2014-03-06 | 公開日 | 2014-04-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism. J.Biol.Chem., 289, 2014
|
|
3TID
| Crystal structure of the LCMV derived peptide GP34 in complex with the murine mhc class I H-2 Kb | 分子名称: | ACETATE ION, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ... | 著者 | Nguyen, T.T, Shen, Z.T, Stern, L.J. | 登録日 | 2011-08-20 | 公開日 | 2012-08-22 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Disparate epitopes mediating protective heterologous immunity to unrelated viruses share peptide-MHC structural features recognized by cross-reactive T cells. J.Immunol., 191, 2013
|
|
3TWC
| |
2R23
| Crystal structure of S25-2 Fab in complex with Kdo analogues | 分子名称: | D-glycero-alpha-D-talo-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ... | 著者 | Brooks, C.L, Evans, S.V. | 登録日 | 2007-08-24 | 公開日 | 2008-12-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. J.Mol.Biol., 377, 2008
|
|
5NMK
| HLA A02 presenting SLFNTIAVL | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | 登録日 | 2017-04-06 | 公開日 | 2017-11-15 | 最終更新日 | 2017-12-20 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope. Front Immunol, 8, 2017
|
|
6JP3
| Crystal structure of peptide in complex with HLA-A1101. | 分子名称: | ALA-MET-TYR-LYS, ALA-THR-ILE-GLY-THR, Beta-2-microglobulin, ... | 著者 | Huan, X, Xiao, Z, Ren, E.C. | 登録日 | 2019-03-25 | 公開日 | 2020-01-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Crystal structure of suboptimal viral fragments of Epstein Barr Virus Rta peptide-HLA complex that stimulate CD8 T cell response. Sci Rep, 9, 2019
|
|
3WL9
| HLA-A24 in complex with HIV-1 Nef126-10(8I10F) | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-24 alpha chain, ... | 著者 | Shimizu, A, Fukai, S, Yamagata, A, Iwamoto, A, Han, C. | 登録日 | 2013-11-08 | 公開日 | 2014-06-11 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Switching and emergence of CTL epitopes in HIV-1 infection Retrovirology, 11, 2014
|
|
5JIH
| Crystal structure of HER2 binding IgG1-Fc (Fcab STAB19) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | 著者 | Humm, A, Lobner, E, Mlynek, G, Obinger, C, Djinovic-Carugo, K. | 登録日 | 2016-04-22 | 公開日 | 2017-04-12 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.663 Å) | 主引用文献 | Fcab-HER2 Interaction: a Menage a Trois. Lessons from X-Ray and Solution Studies. Structure, 25, 2017
|
|
8EMK
| |
7P3D
| MHC I A02 Allele presenting YLQPRTFLL | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... | 著者 | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | 登録日 | 2021-07-07 | 公開日 | 2021-07-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell, 185, 2022
|
|
3UTQ
| Human HLA-A*0201-ALWGPDPAAA | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Rizkallah, P.J, Cole, D.K, Sewell, A.K, Bulek, A.M. | 登録日 | 2011-11-26 | 公開日 | 2012-01-25 | 最終更新日 | 2012-03-07 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Structural basis for the killing of human beta cells by CD8(+) T cells in type 1 diabetes. Nat.Immunol., 13, 2012
|
|
7T5M
| Structure of HLA-A*02:01-FLPTPEELGLLGPPRPQVLA complex | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-2-microglobulin, Interleukin-27 receptor subunit alpha, ... | 著者 | Gras, S. | 登録日 | 2021-12-12 | 公開日 | 2022-12-14 | 最終更新日 | 2024-01-03 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Cutting Edge: Unconventional CD8 + T Cell Recognition of a Naturally Occurring HLA-A*02:01-Restricted 20mer Epitope. J Immunol., 208, 2022
|
|
6C6F
| |
3QFD
| |
4U6X
| Crystal Structure of HLA-A*0201 in complex with ALQDA, a 15 mer self-peptide | 分子名称: | ALQDA peptide, ALQDAGDSSRKEYFI, Beta-2-microglobulin, ... | 著者 | Gras, S, Chabrol, E, Rossjohn, J. | 登録日 | 2014-07-30 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Naturally Processed Non-canonical HLA-A*02:01 Presented Peptides. J.Biol.Chem., 290, 2015
|
|