6P2S

Structure of a nested set of N-terminally extended MHC I-peptides provide novel insights into antigen processing and presentation

Summary for 6P2S

Entry DOI	10.2210/pdb6p2s/pdb
Descriptor	MHC class I antigen, Beta-2-microglobulin, MHC I-peptide, ... (4 entities in total)
Functional Keywords	mhc i antigen processing, mhc i antigen presentation, mhc i structure, mhc i immunopeptide, immune system
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	45021.92
Authors	Li, L.,Batliwala, M.,Bouvier, M. (deposition date: 2019-05-22, release date: 2019-10-16, Last modification date: 2023-10-25)
Primary citation	Li, L.,Batliwala, M.,Bouvier, M. ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation. J.Biol.Chem., 294:18534-18544, 2019 Cited by PubMed: 31601650 DOI: 10.1074/jbc.RA119.010102 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation