PDB: 621 件ウェブページステータス検索Chemie searchBIRD

---

6D1J	Crystal structure of NDM-1 complexed with compound 13 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
6D1A	Crystal structure of NDM-1 complexed with compound 1 分子名称: ACETATE ION, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Pemberton, O.A, Chen, Y. 登録日 2018-04-11 公開日 2019-04-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases. J.Med.Chem., 62, 2019
5ZJC	Crystal structure of NDM-1 in complex with D-captopril derivative CY41 分子名称: (2S)-2-methyl-3-sulfanyl-propan-1-ol, 1,2-ETHANEDIOL, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-20 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Crystal structure of NDM-1 to be published
5ZJ7	Crystal structure of NDM-1 in complex with D-captopril derivative CY22 分子名称: (2R)-2-methyl-N-(phenylmethyl)-3-sulfanyl-propanamide, 1,2-ETHANEDIOL, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-19 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Crystal structure of NDM-1 to be published
5ZJ8	Crystal structure of NDM-1 in complex with D-captopril derivative CY32 分子名称: (2S)-2,3-disulfanylpropan-1-ol, 1,2-ETHANEDIOL, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-19 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Crystal structure of NDM-1 to be published
5ZJ2	Crystal structure of NDM-1 in complex with D-captopril 分子名称: 1-(3-MERCAPTO-2-METHYL-PROPIONYL)-PYRROLIDINE-2-CARBOXYLIC ACID, Metallo-beta-lactamase type 2, ZINC ION 著者 Zhang, H, Hao, Q. 登録日 2018-03-18 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors Bioorg.Med.Chem., 29, 2020
5ZJ1	Crystal structure of NDM-1 in complex with D-captopril derivative CYT-14 分子名称: 1,2-ETHANEDIOL, Metallo-beta-lactamase type 2, ZINC ION, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-18 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.96 Å) 主引用文献 Crystal structure of NDM-1 to be published
6CQS	Sediminispirochaeta smaragdinae SPS-1 metallo-beta-lactamase 分子名称: Beta-lactamase, ZINC ION 著者 Page, R.C, VanPelt, J, Cheng, Z, Crowder, M.W. 登録日 2018-03-16 公開日 2018-08-29 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A Noncanonical Metal Center Drives the Activity of the Sediminispirochaeta smaragdinae Metallo-beta-lactamase SPS-1. Biochemistry, 57, 2018
5ZIO	Crystal structure of NDM-1 in complex with L-captopril 分子名称: L-CAPTOPRIL, Metallo-beta-lactamase type 2, ZINC ION 著者 Zhang, H, Hao, Q. 登録日 2018-03-16 公開日 2019-03-20 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Structure-guided optimization of D-captopril for discovery of potent NDM-1 inhibitors Bioorg.Med.Chem., 29, 2020
5ZGU	Crystal structure of NDM-1 at pH7.0 (HEPES) with 2 molecules per asymmetric unit 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HYDROXIDE ION, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGR	Crystal structure of NDM-1 at pH7.3 (HEPES) in complex with hydrolyzed ampicillin 分子名称: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, GLYCEROL, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGV	Crystal structure of NDM-1 at pH8.0 (Tris) with 2 molecules per asymmetric unit 分子名称: GLYCEROL, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGY	Crystal structure of NDM-1 at pH7.5 (Bis-Tris) with 1 molecule per asymmetric unit 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGW	Crystal structure of NDM-1 at pH7.5 with 1 molecule per asymmetric unit (crystallized at succinate pH5.5 and soaked at succinate pH7.5) 分子名称: 1,2-ETHANEDIOL, GLYCEROL, HYDROXIDE ION, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGT	Crystal structure of NDM-1 at pH7.5 (HEPES) with 2 molecules per asymmetric unit 分子名称: GLYCEROL, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZH1	Crystal structure of NDM-1 at pH7.5 (Imidazole) with 2 molecules per asymmetric unit 分子名称: HYDROXIDE ION, IMIDAZOLE, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGQ	Crystal structure of NDM-1 at pH7.5 (Tris-HCl, (NH4)2SO4) in complex with hydrolyzed ampicillin 分子名称: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGZ	Crystal structure of NDM-1 at pH7.5 (Imidazole) with 1 molecule per asymmetric unit 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGP	Crystal structure of NDM-1 at pH6.2 (Bis-Tris) in complex with hydrolyzed ampicillin 分子名称: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGX	Crystal structure of NDM-1 at pH7.5 (Succinate) with 1 molecule per asymmetric unit 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-10 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGI	Crystal structure of NDM-1 at pH6.5 (Succinate) with 1 molecule per asymmetric unit 分子名称: 1,2-ETHANEDIOL, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-09 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGE	Crystal structure of NDM-1 at pH5.5 (Bis-Tris) in complex with hydrolyzed ampicillin 分子名称: (2R,4S)-2-[(R)-{[(2R)-2-amino-2-phenylacetyl]amino}(carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, HYDROXIDE ION, Metallo-beta-lactamase type 2, ... 著者 Zhang, H, Hao, Q. 登録日 2018-03-08 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
5ZGF	Crystal structure of NDM-1 Q123G mutant 分子名称: HYDROXIDE ION, Metallo-beta-lactamase type 2, ZINC ION 著者 Zhang, H, Hao, Q. 登録日 2018-03-08 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Active-Site Conformational Fluctuations Promote the Enzymatic Activity of NDM-1. Antimicrob. Agents Chemother., 62, 2018
6CGY	Structure of the Quorum Quenching lactonase from Alicyclobacillus acidoterrestris bound to a phosphate anion 分子名称: 1,2-ETHANEDIOL, Beta-lactamase, COBALT (II) ION, ... 著者 Bergonzi, C, Schwab, M, Naik, T, Daude, D, Chabriere, E, Elias, M. 登録日 2018-02-21 公開日 2018-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties. Sci Rep, 8, 2018
6CGZ	Structure of the Quorum Quenching lactonase from Alicyclobacillus acidoterrestris bound to C6-AHL 分子名称: 1,2-ETHANEDIOL, Beta-lactamase, COBALT (II) ION, ... 著者 Bergonzi, C, Schwab, M, Naik, T, Daude, D, Chabriere, E, Elias, M. 登録日 2018-02-21 公開日 2018-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties. Sci Rep, 8, 2018

<45678910111213141516171819>