8DVV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dvv by Molmil](/molmil-images/mine/8dvv) | Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | 著者 | Iyer, K.A, Hu, Y, Murayama, T, Samso, M. | 登録日 | 2022-07-29 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions To Be Published
|
|
8DVE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dve by Molmil](/molmil-images/mine/8dve) | |
8DUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8duj by Molmil](/molmil-images/mine/8duj) | |
8DTZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dtz by Molmil](/molmil-images/mine/8dtz) | |
8DTY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dty by Molmil](/molmil-images/mine/8dty) | |
8DTB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dtb by Molmil](/molmil-images/mine/8dtb) | |
8DRP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8drp by Molmil](/molmil-images/mine/8drp) | |
8DJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dj1 by Molmil](/molmil-images/mine/8dj1) | Crystal structure of NavAb V126T as a basis for the human Nav1.7 Inherited Erythromelalgia S241T mutation | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein | 著者 | Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A. | 登録日 | 2022-06-29 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8DJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dj0 by Molmil](/molmil-images/mine/8dj0) | Crystal structure of NavAb L123T as a basis for the human Nav1.7 Inherited Erythromelalgia I848T mutation | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein | 著者 | Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A. | 登録日 | 2022-06-29 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8DIZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8diz by Molmil](/molmil-images/mine/8diz) | Crystal structure of NavAb I119T as a basis for the human Nav1.7 Inherited Erythromelalgia I234T mutation | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein | 著者 | Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A. | 登録日 | 2022-06-29 | 公開日 | 2023-04-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8DIY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8diy by Molmil](/molmil-images/mine/8diy) | Crystal structure of NavAb L101S as a basis for the human Nav1.7 Inherited Erythromelalgia F216S mutation | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein | 著者 | Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A. | 登録日 | 2022-06-29 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7. J.Gen.Physiol., 155, 2023
|
|
8DIX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dix by Molmil](/molmil-images/mine/8dix) | Structure of NavAb L98R as a basis for the human Nav1.7 Inherited Erythromelalgia L823R mutation | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein | 著者 | Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A. | 登録日 | 2022-06-29 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7. J.Gen.Physiol., 155, 2023
|
|
8DIW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8diw by Molmil](/molmil-images/mine/8diw) | Crystal structure of NavAb E96P as a basis for the human Nav1.7 Inherited Erythromelalgia S211P mutation | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein | 著者 | Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A. | 登録日 | 2022-06-29 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7. J.Gen.Physiol., 155, 2023
|
|
8DIV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8div by Molmil](/molmil-images/mine/8div) | Crystal structure of NavAb I22V as a basis for the human Nav1.7 Inherited Erythromelalgia I136V mutation | 分子名称: | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ... | 著者 | Wisedchaisri, G, Gamal El-Din, T.M, Powell, N.M, Zheng, N, Catterall, W.A. | 登録日 | 2022-06-29 | 公開日 | 2023-10-25 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7. J.Gen.Physiol., 155, 2023
|
|
8DFL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dfl by Molmil](/molmil-images/mine/8dfl) | |
8DDX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ddx by Molmil](/molmil-images/mine/8ddx) | cryo-EM structure of TRPM3 ion channel in complex with Gbg in the presence of PIP2, tethered by ALFA-nanobody | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2022-06-19 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111, 2023
|
|
8DDW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ddw by Molmil](/molmil-images/mine/8ddw) | |
8DDV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ddv by Molmil](/molmil-images/mine/8ddv) | Cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state4 | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2022-06-19 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111, 2023
|
|
8DDU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ddu by Molmil](/molmil-images/mine/8ddu) | cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state3 | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2022-06-19 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111, 2023
|
|
8DDT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ddt by Molmil](/molmil-images/mine/8ddt) | cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state2 | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2022-06-18 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111, 2023
|
|
8DDS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dds by Molmil](/molmil-images/mine/8dds) | cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state1 | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2022-06-18 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111, 2023
|
|
8DDR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ddr by Molmil](/molmil-images/mine/8ddr) | cryo-EM structure of TRPM3 ion channel in the absence of PIP2 | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2022-06-18 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111, 2023
|
|
8DDQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ddq by Molmil](/molmil-images/mine/8ddq) | cryo-EM structure of TRPM3 ion channel in the presence of soluble Gbg, focused on channel | 分子名称: | (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ... | 著者 | Zhao, C, MacKinnon, R. | 登録日 | 2022-06-18 | 公開日 | 2022-11-02 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111, 2023
|
|
8BX7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bx7 by Molmil](/molmil-images/mine/8bx7) | Structure of the rod CNG channel bound to calmodulin | 分子名称: | Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1, calmodulin-1 | 著者 | Marino, J. | 登録日 | 2022-12-08 | 公開日 | 2023-04-12 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel. Proc.Natl.Acad.Sci.USA, 120, 2023
|
|
8BDC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bdc by Molmil](/molmil-images/mine/8bdc) | Human apo TRPM8 in a closed state (composite map) | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ... | 著者 | Palchevskyi, S, Czarnocki-Cieciura, M, Vistoli, G, Gervasoni, S, Nowak, E, Beccari, A.R, Nowotny, M, Talarico, C. | 登録日 | 2022-10-19 | 公開日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Structure of human TRPM8 channel. Commun Biol, 6, 2023
|
|