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8DVV
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BU of 8dvv by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-29
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions
To Be Published
8DVE
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BU of 8dve by Molmil
RyR1 in presence of IpCa-T26E phosphomimetic and activating ligands
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-28
公開日2023-05-31
最終更新日2023-07-05
実験手法ELECTRON MICROSCOPY (3.84 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DUJ
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BU of 8duj by Molmil
Global map in C1 of RyR1 particles in complex with ImperaCalcin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-27
公開日2023-05-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DTZ
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BU of 8dtz by Molmil
Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-26
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
8DTY
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BU of 8dty by Molmil
Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2022-07-26
公開日2024-01-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under closed-state conditions
To Be Published
8DTB
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BU of 8dtb by Molmil
Focus/local refined map in C1 of signal subtracted RyR1 particles in complex with ImperaCalcin
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Imperacalcin, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-25
公開日2023-05-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DRP
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BU of 8drp by Molmil
Focus/local refined map in C4 of signal subtracted RyR1 particles
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Ryanodine receptor 1, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-21
公開日2023-05-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
8DJ1
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BU of 8dj1 by Molmil
Crystal structure of NavAb V126T as a basis for the human Nav1.7 Inherited Erythromelalgia S241T mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DJ0
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BU of 8dj0 by Molmil
Crystal structure of NavAb L123T as a basis for the human Nav1.7 Inherited Erythromelalgia I848T mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DIZ
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BU of 8diz by Molmil
Crystal structure of NavAb I119T as a basis for the human Nav1.7 Inherited Erythromelalgia I234T mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-04-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na V 1.7.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DIY
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BU of 8diy by Molmil
Crystal structure of NavAb L101S as a basis for the human Nav1.7 Inherited Erythromelalgia F216S mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.
J.Gen.Physiol., 155, 2023
8DIX
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BU of 8dix by Molmil
Structure of NavAb L98R as a basis for the human Nav1.7 Inherited Erythromelalgia L823R mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.
J.Gen.Physiol., 155, 2023
8DIW
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BU of 8diw by Molmil
Crystal structure of NavAb E96P as a basis for the human Nav1.7 Inherited Erythromelalgia S211P mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein
著者Wisedchaisri, G, Gamal El-Din, T.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.
J.Gen.Physiol., 155, 2023
8DIV
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BU of 8div by Molmil
Crystal structure of NavAb I22V as a basis for the human Nav1.7 Inherited Erythromelalgia I136V mutation
分子名称: 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Ion transport protein, ...
著者Wisedchaisri, G, Gamal El-Din, T.M, Powell, N.M, Zheng, N, Catterall, W.A.
登録日2022-06-29
公開日2023-10-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.
J.Gen.Physiol., 155, 2023
8DFL
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BU of 8dfl by Molmil
Structure of human Kv1.3 with A0194009G09 nanobodies (alternate conformation)
分子名称: Nanobody A0194009G09, POTASSIUM ION, Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion
著者Meyerson, J.R, Selvakumar, P.
登録日2022-06-22
公開日2022-07-13
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators.
Nat Commun, 13, 2022
8DDX
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BU of 8ddx by Molmil
cryo-EM structure of TRPM3 ion channel in complex with Gbg in the presence of PIP2, tethered by ALFA-nanobody
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhao, C, MacKinnon, R.
登録日2022-06-19
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
8DDW
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BU of 8ddw by Molmil
cryo-EM structure of TRPM3 ion channel in complex with Gbg, tethered by ALFA-nanobody
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Transient receptor potential cation channel, ...
著者Zhao, C, MacKinnon, R.
登録日2022-06-19
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
8DDV
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BU of 8ddv by Molmil
Cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state4
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ...
著者Zhao, C, MacKinnon, R.
登録日2022-06-19
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
8DDU
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BU of 8ddu by Molmil
cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state3
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ...
著者Zhao, C, MacKinnon, R.
登録日2022-06-19
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
8DDT
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BU of 8ddt by Molmil
cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state2
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ...
著者Zhao, C, MacKinnon, R.
登録日2022-06-18
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
8DDS
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BU of 8dds by Molmil
cryo-EM structure of TRPM3 ion channel in the presence of PIP2, state1
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ...
著者Zhao, C, MacKinnon, R.
登録日2022-06-18
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
8DDR
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BU of 8ddr by Molmil
cryo-EM structure of TRPM3 ion channel in the absence of PIP2
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ...
著者Zhao, C, MacKinnon, R.
登録日2022-06-18
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
8DDQ
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BU of 8ddq by Molmil
cryo-EM structure of TRPM3 ion channel in the presence of soluble Gbg, focused on channel
分子名称: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, SODIUM ION, ...
著者Zhao, C, MacKinnon, R.
登録日2022-06-18
公開日2022-11-02
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Neuron, 111, 2023
8BX7
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BU of 8bx7 by Molmil
Structure of the rod CNG channel bound to calmodulin
分子名称: Cyclic nucleotide-gated cation channel beta-1, cGMP-gated cation channel alpha-1, calmodulin-1
著者Marino, J.
登録日2022-12-08
公開日2023-04-12
実験手法ELECTRON MICROSCOPY (2.76 Å)
主引用文献Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel.
Proc.Natl.Acad.Sci.USA, 120, 2023
8BDC
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BU of 8bdc by Molmil
Human apo TRPM8 in a closed state (composite map)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHOLESTEROL HEMISUCCINATE, SODIUM ION, ...
著者Palchevskyi, S, Czarnocki-Cieciura, M, Vistoli, G, Gervasoni, S, Nowak, E, Beccari, A.R, Nowotny, M, Talarico, C.
登録日2022-10-19
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Structure of human TRPM8 channel.
Commun Biol, 6, 2023

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