8DIY
Crystal structure of NavAb L101S as a basis for the human Nav1.7 Inherited Erythromelalgia F216S mutation
Summary for 8DIY
Entry DOI | 10.2210/pdb8diy/pdb |
Descriptor | Ion transport protein, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, ... (4 entities in total) |
Functional Keywords | voltage-gated sodium channel ion transport protein, membrane protein |
Biological source | Aliarcobacter butzleri RM4018 |
Total number of polymer chains | 1 |
Total formula weight | 34387.67 |
Authors | Wisedchaisri, G.,Gamal El-Din, T.M.,Zheng, N.,Catterall, W.A. (deposition date: 2022-06-29, release date: 2023-10-25, Last modification date: 2023-11-15) |
Primary citation | Wisedchaisri, G.,Gamal El-Din, T.M.,Powell, N.M.,Zheng, N.,Catterall, W.A. Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7. J.Gen.Physiol., 155:-, 2023 Cited by PubMed: 37903281DOI: 10.1085/jgp.202313450 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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