8DVE
RyR1 in presence of IpCa-T26E phosphomimetic and activating ligands
This is a non-PDB format compatible entry.
Summary for 8DVE
Entry DOI | 10.2210/pdb8dve/pdb |
EMDB information | 27680 27695 27721 27736 |
Descriptor | Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Calmodulin-1, ... (7 entities in total) |
Functional Keywords | ryanodine receptor, ion channel, snake toxin, calcin, complex, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 2380012.76 |
Authors | Haji-Ghassemi, O.,Van Petegm, F. (deposition date: 2022-07-28, release date: 2023-05-31, Last modification date: 2023-07-05) |
Primary citation | Haji-Ghassemi, O.,Chen, Y.S.,Woll, K.,Gurrola, G.B.,Valdivia, C.R.,Cai, W.,Li, S.,Valdivia, H.H.,Van Petegem, F. Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation. Sci Adv, 9:eadf4936-eadf4936, 2023 Cited by PubMed: 37224245DOI: 10.1126/sciadv.adf4936 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.84 Å) |
Structure validation
Download full validation report