8DVE

RyR1 in presence of IpCa-T26E phosphomimetic and activating ligands

This is a non-PDB format compatible entry.

Summary for 8DVE

• Entry DOI: 10.2210/pdb8dve/pdb
• EMDB information: 27680 27695 27721 27736
• Descriptor: Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Calmodulin-1, ... (7 entities in total)
• Functional Keywords: ryanodine receptor, ion channel, snake toxin, calcin, complex, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 2380012.76

Authors

Haji-Ghassemi, O.,Van Petegm, F. (deposition date: 2022-07-28, release date: 2023-05-31, Last modification date: 2023-07-05)

• Primary citation: Haji-Ghassemi, O.,Chen, Y.S.,Woll, K.,Gurrola, G.B.,Valdivia, C.R.,Cai, W.,Li, S.,Valdivia, H.H.,Van Petegem, F.; Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.; Sci Adv, 9:eadf4936-eadf4936, 2023; PubMed: 37224245; DOI: 10.1126/sciadv.adf4936

Experimental method

ELECTRON MICROSCOPY (3.84 Å)