4FP4
| Crystal structure of isoprenoid synthase a3mx09 (target efi-501993) from pyrobaculum calidifontis | 分子名称: | GERAN-8-YL GERAN, Polyprenyl synthetase, UNKNOWN ATOM OR ION, ... | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-06-21 | 公開日 | 2012-07-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
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4F62
| Crystal structure of a putative farnesyl-diphosphate synthase from Marinomonas sp. MED121 (Target EFI-501980) | 分子名称: | CHLORIDE ION, GLYCEROL, Geranyltranstransferase, ... | 著者 | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-05-14 | 公開日 | 2012-06-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
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1TZH
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1TZI
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4JZB
| Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)-3-PHENYLPYRIDINIUM, IPP and Ca2+ | 分子名称: | 1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridinium, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ... | 著者 | Aripirala, S, Amzel, L.M, Gabelli, S. | 登録日 | 2013-04-02 | 公開日 | 2014-02-12 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. Acta Crystallogr.,Sect.D, 70, 2014
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4H5E
| Crystal structure of human FPPS in ternary complex with YS0470 and isopentenyl pyrophosphate | 分子名称: | Farnesyl pyrophosphate synthase, ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION, ... | 著者 | Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2012-09-18 | 公開日 | 2012-12-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
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4KZN
| crystal structure of human VEGF-A receptor binding domain | 分子名称: | SULFATE ION, TRIETHYLENE GLYCOL, Vascular endothelial growth factor A, ... | 著者 | Liaw, Y.C. | 登録日 | 2013-05-30 | 公開日 | 2014-06-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7114 Å) | 主引用文献 | Structural Basis for the Bivalent Glycosylated Human VEGF-A121 and VEGF-A165 in recruiment of Receptor and Co-receptor to be published
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7GPB
| STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Barford, D, Hu, S.-H, Johnson, L.N. | 登録日 | 1990-11-13 | 公開日 | 1992-10-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP. J.Mol.Biol., 218, 1991
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5HN1
| Crystal structure of Interleukin-37 | 分子名称: | Interleukin-37, SULFATE ION | 著者 | Ellisdon, A.M, Nold-Petry, C.A, Nold, M.F, Whisstock, J.C. | 登録日 | 2016-01-17 | 公開日 | 2017-02-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Homodimerization attenuates the anti-inflammatory activity of interleukin-37. Sci Immunol, 2, 2017
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4L22
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4H5D
| Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate | 分子名称: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | 著者 | Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2012-09-18 | 公開日 | 2012-12-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
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4GLS
| Crystal Structure of Chemically Synthesized Heterochiral {D-Protein Antagonist plus VEGF-A} Protein Complex in space group P21 | 分子名称: | D- RFX001, D- Vascular endothelial growth factor-A, DI(HYDROXYETHYL)ETHER, ... | 著者 | Mandal, K, Uppalapati, M, Ault-Riche, D, Kenney, J, Lowitz, J, Sidhu, S, Kent, S.B.H. | 登録日 | 2012-08-14 | 公開日 | 2012-09-05 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography. Proc.Natl.Acad.Sci.USA, 109, 2012
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4L2X
| Crystal structure of human FPPS in complex with magnesium, CL02134, and inorganic pyrophosphate | 分子名称: | ({[6-(4-cyclopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino}methanediyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | 著者 | Park, J, Leung, C.-Y, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2013-06-04 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition. J.Med.Chem., 56, 2013
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4GPB
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1QM5
| Phosphorylase recognition and phosphorylysis of its oligosaccharide substrate: answers to a long outstanding question | 分子名称: | 4-thio-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, MALTODEXTRIN PHOSPHORYLASE, PHOSPHATE ION, ... | 著者 | Watson, K.A, McCleverty, C, Geremia, S, Cottaz, S, Driguez, H, Johnson, L.N. | 登録日 | 1999-09-20 | 公開日 | 2000-02-03 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phosphorylase Recognition and Phosphorolysis of its Oligosaccharide Substrate: Answers to a Long Outstanding Question Embo J., 18, 1999
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7E77
| The structure of cytosolic TaPGI | 分子名称: | Glucose-6-phosphate isomerase | 著者 | Gao, F, Liu, C.M. | 登録日 | 2021-02-25 | 公開日 | 2021-07-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass. New Phytol., 231, 2021
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7E78
| the structure of cytosolic TaPGI with substrate | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, Glucose-6-phosphate isomerase | 著者 | Gao, F, Liu, C.M. | 登録日 | 2021-02-25 | 公開日 | 2021-07-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass. New Phytol., 231, 2021
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7E76
| The structure of chloroplastic TaPGI | 分子名称: | Glucose-6-phosphate isomerase | 著者 | Gao, F, Liu, C.M. | 登録日 | 2021-02-25 | 公開日 | 2021-07-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass. New Phytol., 231, 2021
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2VWE
| Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment | 分子名称: | ANTI-VEGF-B MONOCLONAL ANTIBODY, VASCULAR ENDOTHELIAL GROWTH FACTOR B | 著者 | Leonard, P, Scotney, P.D, Jabeen, T, Iyer, S, Fabri, L.J, Nash, A.D, Acharya, K.R. | 登録日 | 2008-06-23 | 公開日 | 2008-11-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment. J.Mol.Biol., 384, 2008
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4GP2
| Crystal structure of ISOPRENOID SYNTHASE A3MSH1 (TARGET EFI-501992) from pyrobaculum calidifontis complexed with DMAPP and Magnesium | 分子名称: | DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, Polyprenyl synthetase | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-08-20 | 公開日 | 2012-10-10 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Isoprenoid Synthase from Pyrobaculum Calidifontis To be Published
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4H5C
| Crystal structure of human FPPS in ternary complex with YS0470 and inorganic phosphate | 分子名称: | Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. | 登録日 | 2012-09-18 | 公開日 | 2012-12-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
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4KPD
| Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate | 分子名称: | 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ... | 著者 | Barnett, B.L, Tsoumpra, M.K, Muniz, J.R.C, Walter, R.L. | 登録日 | 2013-05-13 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate To be Published
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4GP1
| Crystal structure of ISOPRENOID SYNTHASE A3MSH1 (TARGET EFI-501992) from pyrobaculum calidifontis complexed with DMAPP | 分子名称: | CHLORIDE ION, DIMETHYLALLYL DIPHOSPHATE, Polyprenyl synthetase, ... | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2012-08-20 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Crystal Structure of Isoprenoid Synthase from Pyrobaculum Calidifontis To be Published
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1U0F
| Crystal structure of mouse phosphoglucose isomerase in complex with glucose 6-phosphate | 分子名称: | 6-O-phosphono-alpha-D-glucopyranose, BETA-MERCAPTOETHANOL, GLUCOSE-6-PHOSPHATE, ... | 著者 | Solomons, J.T.G, Zimmerly, E.M, Burns, S, Krishnamurthy, N, Swan, M.K, Krings, S, Muirhead, H, Chirgwin, J, Davies, C. | 登録日 | 2004-07-13 | 公開日 | 2004-11-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening. J.Mol.Biol., 342, 2004
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2VPF
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