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4FP4
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Crystal structure of isoprenoid synthase a3mx09 (target efi-501993) from pyrobaculum calidifontis
分子名称: GERAN-8-YL GERAN, Polyprenyl synthetase, UNKNOWN ATOM OR ION, ...
著者Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-06-21
公開日2012-07-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
4F62
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Crystal structure of a putative farnesyl-diphosphate synthase from Marinomonas sp. MED121 (Target EFI-501980)
分子名称: CHLORIDE ION, GLYCEROL, Geranyltranstransferase, ...
著者Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-05-14
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily.
Proc.Natl.Acad.Sci.USA, 110, 2013
1TZH
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Crystal Structure of the Fab YADS1 Complexed with h-VEGF
分子名称: Fab YADS1 Heavy Chain, Fab YADS1 Light Chain, Vascular endothelial growth factor A
著者Fellouse, F.A, Wiesmann, C, Sidhu, S.S.
登録日2004-07-09
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition
Proc.Natl.Acad.Sci.USA, 101, 2004
1TZI
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Crystal Structure of the Fab YADS2 Complexed with h-VEGF
分子名称: Fab YADS2 Heavy Chain, Fab YADS2 Light Chain, Vascular endothelial growth factor A
著者Fellouse, F.A, Wiesmann, C, Sidhu, S.S.
登録日2004-07-10
公開日2004-08-31
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition
Proc.Natl.Acad.Sci.USA, 101, 2004
4JZB
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Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)-3-PHENYLPYRIDINIUM, IPP and Ca2+
分子名称: 1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridinium, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ...
著者Aripirala, S, Amzel, L.M, Gabelli, S.
登録日2013-04-02
公開日2014-02-12
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates.
Acta Crystallogr.,Sect.D, 70, 2014
4H5E
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Crystal structure of human FPPS in ternary complex with YS0470 and isopentenyl pyrophosphate
分子名称: Farnesyl pyrophosphate synthase, ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION, ...
著者Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M.
登録日2012-09-18
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
Bmc Struct.Biol., 12, 2012
4KZN
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crystal structure of human VEGF-A receptor binding domain
分子名称: SULFATE ION, TRIETHYLENE GLYCOL, Vascular endothelial growth factor A, ...
著者Liaw, Y.C.
登録日2013-05-30
公開日2014-06-04
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7114 Å)
主引用文献Structural Basis for the Bivalent Glycosylated Human VEGF-A121 and VEGF-A165 in recruiment of Receptor and Co-receptor
to be published
7GPB
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BU of 7gpb by Molmil
STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
分子名称: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ...
著者Barford, D, Hu, S.-H, Johnson, L.N.
登録日1990-11-13
公開日1992-10-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
5HN1
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Crystal structure of Interleukin-37
分子名称: Interleukin-37, SULFATE ION
著者Ellisdon, A.M, Nold-Petry, C.A, Nold, M.F, Whisstock, J.C.
登録日2016-01-17
公開日2017-02-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Homodimerization attenuates the anti-inflammatory activity of interleukin-37.
Sci Immunol, 2, 2017
4L22
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BU of 4l22 by Molmil
Crystal structure of putative glycogen phosphorylase from Streptococcus mutans
分子名称: Phosphorylase
著者Lihan, M.-Y, Li, G.-L, Li, L.-F, Su, X.-D.
登録日2013-06-04
公開日2014-06-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of putative glycogen phosphorylase from Streptococcus mutans
To be Published
4H5D
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Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate
分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
著者Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M.
登録日2012-09-18
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
Bmc Struct.Biol., 12, 2012
4GLS
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Crystal Structure of Chemically Synthesized Heterochiral {D-Protein Antagonist plus VEGF-A} Protein Complex in space group P21
分子名称: D- RFX001, D- Vascular endothelial growth factor-A, DI(HYDROXYETHYL)ETHER, ...
著者Mandal, K, Uppalapati, M, Ault-Riche, D, Kenney, J, Lowitz, J, Sidhu, S, Kent, S.B.H.
登録日2012-08-14
公開日2012-09-05
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography.
Proc.Natl.Acad.Sci.USA, 109, 2012
4L2X
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Crystal structure of human FPPS in complex with magnesium, CL02134, and inorganic pyrophosphate
分子名称: ({[6-(4-cyclopropylphenyl)thieno[2,3-d]pyrimidin-4-yl]amino}methanediyl)bis(phosphonic acid), Farnesyl pyrophosphate synthase, MAGNESIUM ION, ...
著者Park, J, Leung, C.-Y, Tsantrizos, Y.S, Berghuis, A.M.
登録日2013-06-04
公開日2014-01-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Thienopyrimidine Bisphosphonate (ThPBP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Optimization and Characterization of the Mode of Inhibition.
J.Med.Chem., 56, 2013
4GPB
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COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
分子名称: 2-deoxy-2-fluoro-1-O-phosphono-alpha-D-glucopyranose, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
著者Martin, J.L, Johnson, L.N.
登録日1990-06-04
公開日1992-10-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
1QM5
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Phosphorylase recognition and phosphorylysis of its oligosaccharide substrate: answers to a long outstanding question
分子名称: 4-thio-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, MALTODEXTRIN PHOSPHORYLASE, PHOSPHATE ION, ...
著者Watson, K.A, McCleverty, C, Geremia, S, Cottaz, S, Driguez, H, Johnson, L.N.
登録日1999-09-20
公開日2000-02-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Phosphorylase Recognition and Phosphorolysis of its Oligosaccharide Substrate: Answers to a Long Outstanding Question
Embo J., 18, 1999
7E77
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BU of 7e77 by Molmil
The structure of cytosolic TaPGI
分子名称: Glucose-6-phosphate isomerase
著者Gao, F, Liu, C.M.
登録日2021-02-25
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
7E78
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the structure of cytosolic TaPGI with substrate
分子名称: 6-O-phosphono-alpha-D-glucopyranose, Glucose-6-phosphate isomerase
著者Gao, F, Liu, C.M.
登録日2021-02-25
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
7E76
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The structure of chloroplastic TaPGI
分子名称: Glucose-6-phosphate isomerase
著者Gao, F, Liu, C.M.
登録日2021-02-25
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Engineering of the cytosolic form of phosphoglucose isomerase into chloroplasts improves plant photosynthesis and biomass.
New Phytol., 231, 2021
2VWE
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BU of 2vwe by Molmil
Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment
分子名称: ANTI-VEGF-B MONOCLONAL ANTIBODY, VASCULAR ENDOTHELIAL GROWTH FACTOR B
著者Leonard, P, Scotney, P.D, Jabeen, T, Iyer, S, Fabri, L.J, Nash, A.D, Acharya, K.R.
登録日2008-06-23
公開日2008-11-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment.
J.Mol.Biol., 384, 2008
4GP2
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Crystal structure of ISOPRENOID SYNTHASE A3MSH1 (TARGET EFI-501992) from pyrobaculum calidifontis complexed with DMAPP and Magnesium
分子名称: DIMETHYLALLYL DIPHOSPHATE, MAGNESIUM ION, Polyprenyl synthetase
著者Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-08-20
公開日2012-10-10
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of Isoprenoid Synthase from Pyrobaculum Calidifontis
To be Published
4H5C
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BU of 4h5c by Molmil
Crystal structure of human FPPS in ternary complex with YS0470 and inorganic phosphate
分子名称: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ...
著者Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M.
登録日2012-09-18
公開日2012-12-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure.
Bmc Struct.Biol., 12, 2012
4KPD
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Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate
分子名称: 1-HYDROXY-2-(3-PYRIDINYL)ETHYLIDENE BIS-PHOSPHONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, ...
著者Barnett, B.L, Tsoumpra, M.K, Muniz, J.R.C, Walter, R.L.
登録日2013-05-13
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal Structure of Human Farnesyl Pyrophosphate Synthase (Y204F) Mutant Complexed with Mg, Risedronate and Isopentenyl Pyrophosphate
To be Published
4GP1
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Crystal structure of ISOPRENOID SYNTHASE A3MSH1 (TARGET EFI-501992) from pyrobaculum calidifontis complexed with DMAPP
分子名称: CHLORIDE ION, DIMETHYLALLYL DIPHOSPHATE, Polyprenyl synthetase, ...
著者Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2012-08-20
公開日2012-08-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal Structure of Isoprenoid Synthase from Pyrobaculum Calidifontis
To be Published
1U0F
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Crystal structure of mouse phosphoglucose isomerase in complex with glucose 6-phosphate
分子名称: 6-O-phosphono-alpha-D-glucopyranose, BETA-MERCAPTOETHANOL, GLUCOSE-6-PHOSPHATE, ...
著者Solomons, J.T.G, Zimmerly, E.M, Burns, S, Krishnamurthy, N, Swan, M.K, Krings, S, Muirhead, H, Chirgwin, J, Davies, C.
登録日2004-07-13
公開日2004-11-02
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of mouse phosphoglucose isomerase at 1.6A resolution and its complex with glucose 6-phosphate reveals the catalytic mechanism of sugar ring opening.
J.Mol.Biol., 342, 2004
2VPF
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VASCULAR ENDOTHELIAL GROWTH FACTOR REFINED TO 1.93 ANGSTROMS RESOLUTION
分子名称: VASCULAR ENDOTHELIAL GROWTH FACTOR
著者Muller, Y.A, De Vos, A.M.
登録日1997-07-29
公開日1998-07-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 A resolution: multiple copy flexibility and receptor binding.
Structure, 5, 1997

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