4KZN

crystal structure of human VEGF-A receptor binding domain

Summary for 4KZN

• Entry DOI: 10.2210/pdb4kzn/pdb
• Descriptor: Vascular endothelial growth factor A, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, TRIETHYLENE GLYCOL, ... (5 entities in total)
• Functional Keywords: vegf a, pdgf family, receptor binding, hormone
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 13592.26

Authors

Liaw, Y.C. (deposition date: 2013-05-30, release date: 2014-06-04, Last modification date: 2023-11-08)

• Primary citation: Shen, S.T.,Huang, P.T.,Shuau, Y.S.,Lee, Y.M.,Chen, Y.J.,Liaw, Y.C.,Lou, K.L.; Structural Basis for the Bivalent Glycosylated Human VEGF-A121 and VEGF-A165 in recruiment of Receptor and Co-receptor; to be published,

Experimental method

X-RAY DIFFRACTION (1.7114 Å)