4KZN
crystal structure of human VEGF-A receptor binding domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Vascular endothelial growth factor A | polymer | 104 | 12289.1 | 1 | UniProt (P15692) Pfam (PF00341) | Homo sapiens (human) | VEGF-A, Vascular permeability factor, VPF |
| 2 | B (B) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1057.0 | 1 | In PDB GlyTouCan (G82348BZ) | |||
| 3 | C (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 4 | D (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | E (A) | water | water | 18.0 | 63 | Chemie (HOH) |
Sequence modifications
A: 13 - 109 (UniProt: P15692)
| PDB | External Database | Details |
|---|---|---|
| Ser 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12289.1 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1057.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 246.2 | |
| All* | Total formula weight | 13592.3 |
