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3EW3
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the 1:2 complex between a Nterminal elongated prolactin and the extra cellular domain of the rat prolactin receptor
分子名称: Prolactin, Prolactin receptor
著者Broutin, I, Jomain, J.B, England, P, Goffin, V.
登録日2008-10-14
公開日2009-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2.
J.Biol.Chem., 285, 2010
3F7P
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BU of 3f7p by Molmil
Crystal structure of a complex between integrin beta4 and plectin
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ...
著者de Pereda, J.M.
登録日2008-11-10
公開日2009-03-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis of the interaction between integrin alpha6beta4 and plectin at the hemidesmosomes
Embo J., 28, 2009
3FL7
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BU of 3fl7 by Molmil
Crystal structure of the human ephrin A2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ephrin receptor, ...
著者Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2008-12-18
公開日2009-01-27
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Architecture of Eph receptor clusters.
Proc.Natl.Acad.Sci.USA, 107, 2010
8VJC
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BU of 8vjc by Molmil
Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation.
分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2024-01-06
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8QY4
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BU of 8qy4 by Molmil
Structure of interleukin 11 (gp130 P496L mutant).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ...
著者Gardner, S, Bubeck, D, Jin, Y.
登録日2023-10-25
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Structure of interleukin 11 (gp130 P496L mutant).
To Be Published
8QY5
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Structure of interleukin 6.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
著者Gardner, S, Bubeck, D, Jin, Y.
登録日2023-10-25
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structure of interleukin 6.
To Be Published
8VJB
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BU of 8vjb by Molmil
Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation.
分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2024-01-06
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8QY6
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BU of 8qy6 by Molmil
Structure of interleukin 6 (gp130 P496L mutant).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ...
著者Gardner, S, Bubeck, D, Jin, Y.
登録日2023-10-25
公開日2024-02-21
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structure of interleukin 6 (gp130 P496L mutant).
To Be Published
8U4E
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BU of 8u4e by Molmil
Cryo-EM structure of long form insulin receptor (IR-B) with three IGF2 bound, asymmetric conformation.
分子名称: Insulin receptor, Insulin-like growth factor II
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2023-09-10
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8U4B
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BU of 8u4b by Molmil
Cryo-EM structure of long form insulin receptor (IR-B) in the apo state
分子名称: Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2023-09-10
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8U4C
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BU of 8u4c by Molmil
Cryo-EM structure of long form insulin receptor (IR-B) with four IGF2 bound, symmetric conformation.
分子名称: Insulin receptor, Insulin-like growth factor II
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2023-09-10
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8TAN
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BU of 8tan by Molmil
CryoEM structure of MFRV-VILP bound to IGF1Rzip
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor, ...
著者Kirk, N.S.
登録日2023-06-27
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.05 Å)
主引用文献A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression.
Mol Metab, 80, 2024
4GH7
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BU of 4gh7 by Molmil
Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8
分子名称: Fibronectin, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Gebauer, M, Skerra, A.
登録日2012-08-07
公開日2012-12-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin
J.Mol.Biol., 425, 2013
7STJ
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BU of 7stj by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 1)
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-14
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STK
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BU of 7stk by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulins bound) asymmetric conformation (Conformation 2)
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-14
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STH
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BU of 7sth by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (2 insulin bound) symmetric conformation
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-13
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
7STI
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BU of 7sti by Molmil
Full-length insulin receptor bound with unsaturated insulin WT (1 insulin bound) asymmetric conformation
分子名称: Insulin, Insulin receptor
著者Bai, X.C, Choi, E.
登録日2021-11-13
公開日2022-03-30
最終更新日2022-04-27
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Synergistic activation of the insulin receptor via two distinct sites.
Nat.Struct.Mol.Biol., 29, 2022
4BK5
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BU of 4bk5 by Molmil
crystal structure of the human EphA4 ectodomain in complex with human ephrin A5 (amine-methylated sample)
分子名称: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5
著者Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
登録日2013-04-22
公開日2013-07-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BKA
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BU of 4bka by Molmil
crystal structure of the human EphA4 ectodomain in complex with human ephrin A5
分子名称: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5
著者Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
登録日2013-04-23
公開日2013-07-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (5.3 Å)
主引用文献Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BKF
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BU of 4bkf by Molmil
crystal structure of the human EphA4 ectodomain in complex with human ephrinB3
分子名称: EPHRIN TYPE-A RECEPTOR 4, EPHRIN-B3
著者Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
登録日2013-04-24
公開日2013-07-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (4.65 Å)
主引用文献Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BK4
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BU of 4bk4 by Molmil
crystal structure of the human EphA4 ectodomain
分子名称: EPHRIN TYPE-A RECEPTOR 4
著者Seiradake, E, Schaupp, A, del Toro Ruiz, D, Kaufmann, R, Mitakidis, N, Harlos, K, Aricescu, A.R, Klein, R, Jones, E.Y.
登録日2013-04-22
公開日2013-07-03
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses
Nat.Struct.Mol.Biol., 20, 2013
4BQ6
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BU of 4bq6 by Molmil
Crystal structure of the RGMB-NEO1 complex form 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NEOGENIN, RGM DOMAIN FAMILY MEMBER B
著者Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
登録日2013-05-30
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
7U7N
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BU of 7u7n by Molmil
IL-27 quaternary receptor signaling complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ...
著者Caveney, N.A, Glassman, C.R, Jude, K.M, Tsutsumi, N, Garcia, K.C.
登録日2022-03-07
公開日2022-05-25
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structure of the IL-27 quaternary receptor signaling complex.
Elife, 11, 2022
4BQ7
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Crystal structure of the RGMB-Neo1 complex form 2
分子名称: NEOGENIN, RGM DOMAIN FAMILY MEMBER B
著者Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
登録日2013-05-30
公開日2013-06-12
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (6.601 Å)
主引用文献Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013
4BQ8
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Crystal structure of the RGMB-NEO1 complex form 3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NEOGENIN, RGM DOMAIN FAMILY MEMBER B
著者Bell, C.H, Healey, E, van Erp, S, Bishop, B, Tang, C, Gilbert, R.J.C, Aricescu, A.R, Pasterkamp, R.J, Siebold, C.
登録日2013-05-30
公開日2013-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the Repulsive Guidance Molecule (Rgm)-Neogenin Signaling Hub
Science, 341, 2013

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