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4BH9
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A structural model of CAP mutant (T127L and S128I) in the apo state
分子名称: cAMP-activated global transcriptional regulator CRP
著者Tzeng, S.R, Kalodimos, C.G.
登録日2013-03-30
公開日2013-05-08
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Allosteric inhibition through suppression of transient conformational states.
Nat. Chem. Biol., 9, 2013
4AVC
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Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
分子名称: 1,2-ETHANEDIOL, ACETYL COENZYME *A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
著者Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
登録日2012-05-24
公開日2012-07-11
最終更新日2012-08-22
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4AVB
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BU of 4avb by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ...
著者Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
登録日2012-05-24
公開日2012-07-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4AVA
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BU of 4ava by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ...
著者Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
登録日2012-05-24
公開日2012-07-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
3UKV
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BU of 3ukv by Molmil
Structure of the C-linker/CNBHD of zELK channels in P 1 21 1 space group, crystallized in the presence of cAMP
分子名称: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family
著者Brelidze, T.I.
登録日2011-11-09
公開日2012-01-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure of the carboxy-terminal region of a KCNH channel.
Nature, 481, 2012
3UKT
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Structure of the C-linker/CNBHD of zELK channels in P1 21 1 space group
分子名称: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family
著者Brelidze, T.I.
登録日2011-11-09
公開日2012-01-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the carboxy-terminal region of a KCNH channel.
Nature, 481, 2012
3UKN
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BU of 3ukn by Molmil
Structure of the C-linker/CNBHD of zELK channels in C 2 2 21 space group
分子名称: Novel protein similar to vertebrate potassium voltage-gated channel, subfamily H (Eag-related) family
著者Brelidze, T.I.
登録日2011-11-09
公開日2012-01-04
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of the carboxy-terminal region of a KCNH channel.
Nature, 481, 2012
3U11
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Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3U10
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BU of 3u10 by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3U0Z
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BU of 3u0z by Molmil
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lolicato, M, Nardini, M, Gazzarrini, S, Moller, S, Bertinetti, D, Herberg, F.W, Bolognesi, M, Martin, H, Fasolini, M, Bertrand, J.A, Arrigoni, C, Thiel, G, Moroni, A.
登録日2011-09-29
公開日2011-10-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286, 2011
3TNQ
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Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein kinase, ...
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2012-09-26
実験手法X-RAY DIFFRACTION (3.097 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
3TNP
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Structure and Allostery of the PKA RIIb Tetrameric Holoenzyme
分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit
著者Zhang, P, Smith-Nguyen, E.V, Keshwani, M.M, Deal, M.S, Kornev, A.P, Taylor, S.S.
登録日2011-09-01
公開日2012-02-01
最終更新日2013-02-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure and allostery of the PKA RIIbeta tetrameric holoenzyme
Science, 335, 2012
3SHR
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BU of 3shr by Molmil
Crystal Structure of cGMP-dependent Protein Kinase Reveals Novel Site of Interchain Communication
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, SULFATE ION, cGMP-dependent protein kinase 1
著者Osborne, B.W, Wu, J, Taylor, S.S, Dostmann, W.R.
登録日2011-06-16
公開日2011-09-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication.
Structure, 19, 2011
3RYR
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BU of 3ryr by Molmil
Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator
著者Knapp, J, White, M.A, Lee, J.C.
登録日2011-05-11
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Domain-Domain Flexibility Leads to Allostery within the Cam Receptor Protein (Crp)
To be Published
3RYP
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BU of 3ryp by Molmil
Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, GLYCEROL
著者Knapp, J, White, M.A, Lee, J.C.
登録日2011-05-11
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Domain-Domain Flexibility Leads to Allostery within the Cam Receptor Protein (Crp)
To be Published
3RPQ
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BU of 3rpq by Molmil
Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, PHOSPHATE ION
著者Knapp, J, White, M.A, Lee, J.C.
登録日2011-04-27
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Domain-Domain Flexibility Leads to Allostery within the Cam Receptor Protein (Crp)
To be Published
3ROU
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BU of 3rou by Molmil
Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator
著者Knapp, J, White, M.A, Lee, J.C.
登録日2011-04-26
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Domain-Domain Flexibility Leads to Allostery within the Cam Receptor Protein (Crp)
To be Published
3RDI
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BU of 3rdi by Molmil
Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator
著者Knapp, J, White, M.A, Lee, J.C.
登録日2011-04-01
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Domain-Domain Flexibility Leads to Allostery within the Cam Receptor Protein (Crp)
To be Published
3R6S
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BU of 3r6s by Molmil
Crystal structure of GlxR transcription factor from Corynebacterium glutamicum with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, HEXANE-1,6-DIOL, transcription regulator
著者Jungwirth, B, Pojer, F.
登録日2011-03-22
公開日2012-03-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal structure of GlxR transcription factor from Corynebacterium glutamicum with cAMP
To be Published
3QOP
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BU of 3qop by Molmil
Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, GLYCEROL
著者Knapp, J, White, M.A, Lee, J.C.
登録日2011-02-10
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Domain-Domain Flexibility Leads to Allostery within the Camp Receptor Protein (Crp)
To be Published
3PVB
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BU of 3pvb by Molmil
Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
分子名称: GLYCEROL, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Boettcher, A.J, Wu, J, Kim, C, Yang, J, Bruystens, J, Cheung, N, Pennypacker, J.K, Blumenthal, D.A, Kornev, A.P, Taylor, S.S.
登録日2010-12-06
公開日2011-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure of (73-244)RIa:C holoenzyme of cAMP-dependent Protein kinase
Structure, 19, 2011
3PNA
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BU of 3pna by Molmil
Crystal Structure of cAMP bound (91-244)RIa Subunit of cAMP-dependent Protein Kinase
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, GLYCEROL, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Kim, C, Taylor, S.
登録日2010-11-18
公開日2011-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.503 Å)
主引用文献Cyclic AMP Analog Blocks Kinase Activation by Stabilizing Inactive Conformation: Conformational Selection Highlights a New Concept in Allosteric Inhibitor Design.
Mol Cell Proteomics, 10, 2011
3PLQ
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BU of 3plq by Molmil
Crystal structure of PKA type I regulatory subunit bound with Rp-8-Br-cAMPS
分子名称: (2R,4aR,6R,7R,7aS)-6-(6-amino-8-bromo-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-sulfide, ZINC ION, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Swaminathan, K.
登録日2010-11-15
公開日2010-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cyclic AMP analog blocks kinase activation by stabilizing inactive conformation: Conformational selection highlights a new concept in allosteric inhibitor design
To be Published
3OTF
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BU of 3otf by Molmil
Structural basis for the cAMP-dependent gating in human HCN4 channel
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
著者Xu, X, Vysotskaya, Z.V, Liu, Q, Zhou, L.
登録日2010-09-11
公開日2010-10-13
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the cAMP-dependent gating in the human HCN4 channel.
J.Biol.Chem., 285, 2010
3OGJ
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BU of 3ogj by Molmil
Crystal structure of partial apo (92-227) of cGMP-dependent protein kinase
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, PRKG1 protein
著者Kim, J.J, Huang, G, Kwon, T.K, Zwart, P, Headd, J, Kim, C.
登録日2010-08-16
公開日2011-05-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.751 Å)
主引用文献Co-Crystal Structures of PKG Ibeta (92-227) with cGMP and cAMP Reveal the Molecular Details of Cyclic-Nucleotide Binding
Plos One, 6, 2011

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