3OTF

Structural basis for the cAMP-dependent gating in human HCN4 channel

Summary for 3OTF

Entry DOI	10.2210/pdb3otf/pdb
Descriptor	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
Functional Keywords	cyclic-nucleotide binding, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	26217.65
Authors	Xu, X.,Vysotskaya, Z.V.,Liu, Q.,Zhou, L. (deposition date: 2010-09-11, release date: 2010-10-13, Last modification date: 2023-09-06)
Primary citation	Xu, X.,Vysotskaya, Z.V.,Liu, Q.,Zhou, L. Structural basis for the cAMP-dependent gating in the human HCN4 channel. J.Biol.Chem., 285:37082-37091, 2010 Cited by PubMed: 20829353 DOI: 10.1074/jbc.M110.152033 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation