3OTF
Structural basis for the cAMP-dependent gating in human HCN4 channel
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CMP A 725 |
| Chain | Residue |
| A | PHE658 |
| A | GLY659 |
| A | GLU660 |
| A | ILE661 |
| A | CYS662 |
| A | ARG669 |
| A | THR670 |
| A | ARG710 |
Functional Information from PROSITE/UniProt
| site_id | PS00888 |
| Number of Residues | 17 |
| Details | CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIrEGTiGKkMYFIqhG |
| Chain | Residue | Details |
| A | ILE622-GLY638 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20829353, ECO:0000269|PubMed:22006928 |
| Chain | Residue | Details |
| A | GLY659 | |
| A | ARG669 | |
| A | ARG710 |
