3OTF
Structural basis for the cAMP-dependent gating in human HCN4 channel
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | polymer | 220 | 25888.4 | 1 | UniProt (Q9Y3Q4) Pfam (PF00027) | Homo sapiens (human) | |
| 2 | B (A) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 1 | Chemie (CMP) PubChem (23902375) PubChem (25322948) PubChem (40467852) PubChem (44629928) PubChem (176488666) PubChem (25322946) PubChem (59350541) PubChem (274) PubChem (56973690) PubChem (59909322) PubChem (59968988) PubChem (6604194) PubChem (70878457) PubChem (6076) PubChem (216878) PubChem (163043517) PubChem (3080770) PubChem (3246347) PubChem (124132380) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (129317551) PubChem (131841987) PubChem (134693155) PubChem (138107790) PubChem (12071879) PubChem (12866365) PubChem (163043518) | |||
| 3 | C (A) | water | water | 18.0 | 29 | Chemie (HOH) |
Sequence modifications
A: 521 - 739 (UniProt: Q9Y3Q4)
| PDB | External Database | Details |
|---|---|---|
| Ser 520 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 25888.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 329.2 | |
| All* | Total formula weight | 26217.6 |
