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3OTF

Structural basis for the cAMP-dependent gating in human HCN4 channel

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4polymer22025888.41UniProt (Q9Y3Q4)
Pfam (PF00027)
Homo sapiens (human)
2B
(A)
ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATEnon-polymer329.21Chemie (CMP)
3C
(A)
waterwater18.029Chemie (HOH)
Sequence modifications
A: 521 - 739 (UniProt: Q9Y3Q4)
PDBExternal DatabaseDetails
Ser 520-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight25888.4
Non-Polymers*Number of molecules1
Total formula weight329.2
All*Total formula weight26217.6
*Water molecules are not included.

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PDB entries from 2026-02-04

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