9B61
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9B6A
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9B67
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9B69
| GluA2 flip Q in complex with TARPgamma2 at pH8, class12, structure of NTD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform Flip of Glutamate receptor 2, ... | 著者 | Nakagawa, T, Greger, I.H. | 登録日 | 2024-03-23 | 公開日 | 2024-07-31 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization. Nat.Struct.Mol.Biol., 2024
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9B68
| GluA2 flip Q in complex with TARPgamma2 at pH8, class1, structure of NTD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform Flip of Glutamate receptor 2, ... | 著者 | Nakagawa, T, Greger, I.H. | 登録日 | 2024-03-23 | 公開日 | 2024-07-31 | 最終更新日 | 2024-09-04 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization. Nat.Struct.Mol.Biol., 2024
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8YS2
| Overall structure of Eastern Equine Encephalitis virus VLP in complex with the receptor VLDLR LA1-2 | 分子名称: | CALCIUM ION, Capsid protein, Spike glycoprotein E1, ... | 著者 | Cao, D, Ma, B, Cao, Z, Xu, X, Zhang, X, Xiang, Y. | 登録日 | 2024-03-22 | 公開日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (5.2 Å) | 主引用文献 | The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes. Nat Commun, 15, 2024
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8YS4
| Overall structure of Eastern Equine Encephalitis virus VLP in complex with the receptor VLDLR LA3-5 | 分子名称: | CALCIUM ION, Capsid protein, Spike glycoprotein E1, ... | 著者 | Cao, D, Ma, B, Cao, Z, Xu, X, Zhang, X, Xiang, Y. | 登録日 | 2024-03-22 | 公開日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | The receptor VLDLR binds Eastern Equine Encephalitis virus through multiple distinct modes. Nat Commun, 15, 2024
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8YRG
| CryoEM structure of fospropofol-bound MRGPRX4-Gq complex | 分子名称: | Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Cao, C, Fay, J.F, Roth, B.L. | 登録日 | 2024-03-21 | 公開日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model. Sci Transl Med, 16, 2024
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8YR4
| Cryo-EM structure of the human ABCB6 in complex with Cd(II):Phytochelatin 2 | 分子名称: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GAMMA-D-GLUTAMIC ACID, ... | 著者 | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | 登録日 | 2024-03-20 | 公開日 | 2024-06-19 | 最終更新日 | 2024-09-25 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7, 2024
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9B3Q
| The structure of the human cardiac F-actin mutant A331P | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | 著者 | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | 登録日 | 2024-03-20 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of human cardiac actin To Be Published
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9EPZ
| Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3337 | 分子名称: | 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... | 著者 | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2024-03-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting. Eur.J.Med.Chem., 276, 2024
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9EPX
| Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3331 | 分子名称: | 1,2-ETHANEDIOL, 7-[(2-chloranyl-1,3-benzothiazol-6-yl)sulfonyl]-~{N}-[(3-chloranyl-4-phenyl-phenyl)methyl]-7-azaspiro[3.5]nonan-2-amine, Casein kinase II subunit alpha, ... | 著者 | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2024-03-20 | 公開日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3331 To Be Published
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9EQ1
| Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJM24 | 分子名称: | 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... | 著者 | Kraemer, A, Greco, F, Moeckel, J, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2024-03-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting. Eur.J.Med.Chem., 276, 2024
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9EPY
| Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3330 | 分子名称: | 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION, ... | 著者 | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2024-03-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting. Eur.J.Med.Chem., 276, 2024
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9EPW
| Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC3336 | 分子名称: | Casein kinase II subunit alpha, SULFATE ION, ~{N}-[(3-chloranyl-4-phenyl-phenyl)methyl]-2-[1-(3-methylquinolin-8-yl)sulfonylpiperidin-4-yl]ethanamine | 著者 | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2024-03-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting. Eur.J.Med.Chem., 276, 2024
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9EQ0
| Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGJG12 | 分子名称: | Casein kinase II subunit alpha, SULFATE ION, ~{N}-[4-[(3-chloranyl-4-phenyl-phenyl)methylamino]butyl]isoquinoline-5-sulfonamide | 著者 | Kraemer, A, Greco, F, Gerninghaus, J, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2024-03-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting. Eur.J.Med.Chem., 276, 2024
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9EPV
| Crystal structure of human Casein Kinase II subunit alpha (CK2a1) in complex with allosteric ligand FGC333 | 分子名称: | 1,2-ETHANEDIOL, 5-[[2-[(3-chloranyl-4-phenyl-phenyl)methylamino]-7-azaspiro[3.5]nonan-7-yl]sulfonyl]-1,3-dimethyl-benzimidazol-2-one, Casein kinase II subunit alpha, ... | 著者 | Kraemer, A, Greco, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2024-03-20 | 公開日 | 2024-05-01 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Synthesis and evaluation of chemical linchpins for highly selective CK2 alpha targeting. Eur.J.Med.Chem., 276, 2024
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9B3S
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8YR3
| Cryo-EM structure of the human ABCB6 in complex with Cd(II):GSH | 分子名称: | ATP-binding cassette sub-family B member 6, CADMIUM ION, GLUTATHIONE | 著者 | Choi, S.H, Lee, S.S, Lee, H.Y, Kim, S, Kim, J.W, Jin, M.S. | 登録日 | 2024-03-20 | 公開日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structure of cadmium-bound human ABCB6. Commun Biol, 7, 2024
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9B4H
| Chlamydomonas reinhardtii mastigoneme filament | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain-containing protein, Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein, ... | 著者 | Dai, J, Ma, M, Zhang, R, Brown, A. | 登録日 | 2024-03-20 | 公開日 | 2024-04-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mastigoneme structure reveals insights into the O-linked glycosylation code of native hydroxyproline-rich helices. Cell, 2024
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9B3R
| The structure of human cardiac F-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha cardiac muscle 1, ... | 著者 | Doran, M.H, Sousa, D, Rynkiewicz, M.J, Lehman, W, Cammarato, A. | 登録日 | 2024-03-20 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of human cardiac actin To Be Published
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8YQQ
| Structure of HKU1B RBD with TMPRSS2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, Transmembrane protease serine 2 | 著者 | Gao, X, Cui, S, Ding, W, Zhu, K, Shang, K, Zhu, H. | 登録日 | 2024-03-19 | 公開日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.95 Å) | 主引用文献 | Structural basis for the interaction between human coronavirus HKU1 spike receptor binding domain and its receptor TMPRSS2. Cell Discov, 10, 2024
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9B3D
| mDia1 in the middle of F-actin | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | 著者 | Palmer, N.J, Barrie, K.R, Dominguez, R. | 登録日 | 2024-03-19 | 公開日 | 2024-05-29 | 最終更新日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | 主引用文献 | Mechanisms of actin filament severing and elongation by formins. Nature, 632, 2024
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9B35
| Ligand-binding and transmembrane domains of kainate receptor GluK2 in the open state, a complex with agonist glutamate and positive allosteric modulator BPAM344 | 分子名称: | GLUTAMIC ACID, Glutamate receptor ionotropic, kainate 2 | 著者 | Nadezhdin, K.D, Gangwar, S.P, Sobolevsky, A.I. | 登録日 | 2024-03-18 | 公開日 | 2024-05-22 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Kainate receptor channel opening and gating mechanism. Nature, 630, 2024
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9EP8
| Crystal structure of ROCK2 in complex with a 8-(azaindolyl)-benzoazepinone inhibitor | 分子名称: | 1,2-ETHANEDIOL, 8-(azaindolyl)-benzoazepinone, Rho-associated protein kinase 2 | 著者 | Pala, D, Clark, D, Pioselli, B, Accetta, A, Rancati, F. | 登録日 | 2024-03-18 | 公開日 | 2024-09-25 | 最終更新日 | 2024-10-02 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Design and synthesis of novel 8-(azaindolyl)-benzoazepinones as potent and selective ROCK inhibitors. Rsc Med Chem, 2024
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