PDB: 66212 件ウェブページステータス検索Chemie searchBIRD

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7M2Z	Monomeric single-particle reconstruction of the Yeast gamma-TuSC 分子名称: GUANOSINE-5'-DIPHOSPHATE, Spindle pole body component SPC97, Spindle pole body component SPC98, ... 著者 Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A. 登録日 2021-03-17 公開日 2021-05-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation. Elife, 10, 2021
7M2W	Engineered disulfide cross-linked closed conformation of the Yeast gamma-TuRC(SS) 分子名称: GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component 110, Spindle pole body component SPC97, ... 著者 Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A. 登録日 2021-03-17 公開日 2021-05-12 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation. Elife, 10, 2021
7MSL	Structure of anti-CRISPR AcrIIC4 from Haemophilus parainfluenzae 分子名称: AcrIIC4, IODIDE ION 著者 Pan, C, Maxwell, K.L, Moraes, T.F. 登録日 2021-05-11 公開日 2022-03-23 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4 Hpa. J.Mol.Biol., 434, 2022
5BRL	Crystal Structure of L124D STARD4 分子名称: StAR-related lipid transfer protein 4 著者 Iaea, D.B, Dikiy, I, Kiburu, I, Eliezer, D.E, Maxfield, F.R. 登録日 2015-05-31 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 STARD4 Membrane Interactions and Sterol Binding. Biochemistry, 54, 2015
5W9C	Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S in Complex with 4-hydroxytamoxifen 分子名称: 4-HYDROXYTAMOXIFEN, Estrogen receptor 著者 Fanning, S.W, Greene, G.W. 登録日 2017-06-23 公開日 2018-06-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.802 Å) 主引用文献 Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer. Mol. Pharmacol., 94, 2018
4ZA0	Structure of Human Enolase 2 in complex with Phosphonoacetohydroxamate 分子名称: Gamma-enolase, MAGNESIUM ION, PHOSPHONOACETOHYDROXAMIC ACID 著者 Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L. 登録日 2015-04-13 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 SF2312 is a natural phosphonate inhibitor of enolase. Nat.Chem.Biol., 12, 2016
5W9D	Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S Mutant in Complex with Endoxifen 分子名称: Endoxifen, Estrogen receptor 著者 Fanning, S.W, Greene, G.L. 登録日 2017-06-23 公開日 2017-10-11 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.6464 Å) 主引用文献 Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer. Mol. Pharmacol., 94, 2018
4ZCW	Structure of Human Enolase 2 in complex with SF2312 分子名称: Gamma-enolase, MAGNESIUM ION, [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid 著者 Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L. 登録日 2015-04-16 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 SF2312 is a natural phosphonate inhibitor of enolase. Nat.Chem.Biol., 12, 2016
7M1N	Wild-type Hydrogenobacter thermophilus ferredoxin 1 分子名称: IRON/SULFUR CLUSTER, Putative ferredoxin 著者 Steindel, P.S, Li, B, Elliott, S.J. 登録日 2021-03-13 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Maximizing (Electro)catalytic CO2 Reduction with a Ferredoxin-Based Reduction Potential Gradient Acs Catalysis, 11, 2021
7M1O	Hydrogenobacter thermophilus ferredoxin 1 S64A variant 分子名称: IRON/SULFUR CLUSTER, Putative ferredoxin 著者 Steindel, P.S, Li, B, Elliott, S.J. 登録日 2021-03-13 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.98388708 Å) 主引用文献 Maximizing (Electro)catalytic CO2 Reduction with a Ferredoxin-Based Reduction Potential Gradient Acs Catalysis, 11, 2021
3V9V	Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator 分子名称: Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Peroxisome proliferator-activated receptor gamma, methyl 3-{4-[({[(9aS)-8-acetyl-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-yl]carbonyl}amino)methyl]naphthalen-2-yl}propanoate 著者 Matsui, Y, Hanzawa, H. 登録日 2011-12-28 公開日 2012-02-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPAR(gamma) partial agonists Bioorg.Med.Chem.Lett., 22, 2011
3V9T	Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator 分子名称: (9aS)-8-acetyl-N-[(3-ethoxynaphthalen-1-yl)methyl]-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-carboxamide, Peptide from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Peroxisome proliferator-activated receptor gamma 著者 Matsui, Y, Hanzawa, H. 登録日 2011-12-28 公開日 2012-02-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPAR(gamma) partial agonists Bioorg.Med.Chem.Lett., 22, 2012
8JZM	The inhibitor of Toll-like receptor signaling o-vanillin binds covalently to MAL/TIRAP Lys-210 分子名称: Toll/interleukin-1 receptor domain-containing adapter protein 著者 Rahaman, M.H, Jia, X, Maxwell, M.J, Mobli, M, Kobe, B. 登録日 2023-07-05 公開日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2. J Enzyme Inhib Med Chem, 39, 2024
5GIP	Crystal structure of box C/D RNP with 13 nt guide regions and 11 nt substrates 分子名称: 50S ribosomal protein L7Ae, C/D RNA, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ... 著者 Yang, Z, Lin, J, Ye, K. 登録日 2016-06-24 公開日 2016-09-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.129 Å) 主引用文献 Box C/D guide RNAs recognize a maximum of 10 nt of substrates Proc.Natl.Acad.Sci.USA, 113, 2016
5NHR	CRYSTAL STRUCTURE OF THE Activin receptor type-2B LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV, CUBIC CRYSTAL FORM 分子名称: Activin receptor type-2B, Bimagrumab Fv Light-Chain, Bimagrumab Fv heavy-chain 著者 Rondeau, J.-M. 登録日 2017-03-22 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NJ9	E. coli Microcin-processing metalloprotease TldD/E with DRVY angiotensin fragment bound 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ASP-ARG-VAL-TYR, ... 著者 Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. 登録日 2017-03-28 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
5GIN	Crystal structure of box C/D RNP with 12 nt guide regions and 9 nt substrates 分子名称: 50S ribosomal protein L7Ae, C/D RNA, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ... 著者 Yang, Z, Lin, J, Ye, K. 登録日 2016-06-24 公開日 2016-09-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.308 Å) 主引用文献 Box C/D guide RNAs recognize a maximum of 10 nt of substrates Proc.Natl.Acad.Sci.USA, 113, 2016
5NJC	E. coli Microcin-processing metalloprotease TldD/E (TldD E263A mutant) with hexapeptide bound 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Metalloprotease PmbA, ... 著者 Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. 登録日 2017-03-28 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
5NHW	CRYSTAL STRUCTURE OF THE BIMAGRUMAB Fab 分子名称: GLYCEROL, anti-human ActRII Bimagrumab Fab heavy-chain, anti-human ActRII Bimagrumab Fab light-chain 著者 Rondeau, J.-M. 登録日 2017-03-22 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NJ5	E. coli Microcin-processing metalloprotease TldD/E with phosphate bound 分子名称: 1,2-ETHANEDIOL, Metalloprotease PmbA, Metalloprotease TldD, ... 著者 Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. 登録日 2017-03-28 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
5NH3	CRYSTAL STRUCTURE OF THE Activin receptor type-2A LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2A, ... 著者 Scheufler, C. 登録日 2017-03-21 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NJA	E. coli Microcin-processing metalloprotease TldD/E with angiotensin analogue bound 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HIS-PRO-PHE, ... 著者 Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. 登録日 2017-03-28 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
5NGV	CRYSTAL STRUCTURE OF THE Activin receptor type-2B LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV, ORTHORHOMBIC CRYSTAL FORM 分子名称: Activin receptor type-2B, TETRAETHYLENE GLYCOL, anti-human ActRIIB mAb BYM338 heavy-chain, ... 著者 Rondeau, J.-M, Lehmann, S. 登録日 2017-03-20 公開日 2017-11-15 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NJB	E. coli Microcin-processing metalloprotease TldD/E with actinonin bound 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACTINONIN, ... 著者 Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. 登録日 2017-03-28 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017
5NJF	E. coli Microcin-processing metalloprotease TldD/E (TldD H262A mutant) with pentapeptide bound 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ALA-ALA-ALA-ALA-ALA, ... 著者 Ghilarov, D, Serebryakova, M, Stevenson, C.E.M, Hearnshaw, S.J, Volkov, D, Maxwell, A, Lawson, D.M, Severinov, K. 登録日 2017-03-28 公開日 2017-10-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure, 25, 2017

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