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2STA
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BU of 2sta by Molmil
ANIONIC SALMON TRYPSIN IN COMPLEX WITH SQUASH SEED INHIBITOR (CUCURBITA MAXIMA TRYPSIN INHIBITOR I)
分子名称: CALCIUM ION, PROTEIN (TRYPSIN INHIBITOR), PROTEIN (TRYPSIN)
著者Helland, R, Berglund, G.I, Otlewski, J, Apostoluk, W, Andersen, O.A, Willassen, N.P, Smalas, A.O.
登録日1998-12-10
公開日2000-01-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution structures of three new trypsin-squash-inhibitor complexes: a detailed comparison with other trypsins and their complexes.
Acta Crystallogr.,Sect.D, 55, 1999
1ZPQ
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BU of 1zpq by Molmil
STRUCTURE OF BACTERIOPHAGE LAMBDA CII protein
分子名称: Regulatory protein CII
著者Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Joachimiak, A, Darst, S.A, Midwest Center for Structural Genomics (MCSG)
登録日2005-05-17
公開日2005-08-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
1ZS4
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Structure of bacteriophage lambda cII protein in complex with DNA
分子名称: DNA - 27mer, Regulatory protein CII
著者Jain, D, Kim, Y, Maxwell, K.L, Beasley, S, Gussin, G.N, Edwards, A.M, Darst, S.A.
登録日2005-05-23
公開日2005-08-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Bacteriophage lambdacII and Its DNA Complex.
Mol.Cell, 19, 2005
7M1N
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BU of 7m1n by Molmil
Wild-type Hydrogenobacter thermophilus ferredoxin 1
分子名称: IRON/SULFUR CLUSTER, Putative ferredoxin
著者Steindel, P.S, Li, B, Elliott, S.J.
登録日2021-03-13
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Maximizing (Electro)catalytic CO2 Reduction with a Ferredoxin-Based Reduction Potential Gradient
Acs Catalysis, 11, 2021
7M1O
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BU of 7m1o by Molmil
Hydrogenobacter thermophilus ferredoxin 1 S64A variant
分子名称: IRON/SULFUR CLUSTER, Putative ferredoxin
著者Steindel, P.S, Li, B, Elliott, S.J.
登録日2021-03-13
公開日2021-07-28
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.98388708 Å)
主引用文献Maximizing (Electro)catalytic CO2 Reduction with a Ferredoxin-Based Reduction Potential Gradient
Acs Catalysis, 11, 2021
2L04
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The Solution Structure of the C-terminal Ig-like Domain of the Bacteriophage Lambda Tail Tube Protein
分子名称: Major tail protein V
著者Pell, L.G, Gasmi-Seabrook, G.M.C, Donaldson, L.W, Howell, P, Davidson, A.R, Maxwell, K.L.
登録日2010-06-30
公開日2010-09-22
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The Solution Structure of the C-Terminal Ig-like Domain of the Bacteriophage l Tail Tube Protein.
J.Mol.Biol., 403, 2010
7M2W
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Engineered disulfide cross-linked closed conformation of the Yeast gamma-TuRC(SS)
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component 110, Spindle pole body component SPC97, ...
著者Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A.
登録日2021-03-17
公開日2021-05-12
最終更新日2021-05-19
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation.
Elife, 10, 2021
7MSL
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BU of 7msl by Molmil
Structure of anti-CRISPR AcrIIC4 from Haemophilus parainfluenzae
分子名称: AcrIIC4, IODIDE ION
著者Pan, C, Maxwell, K.L, Moraes, T.F.
登録日2021-05-11
公開日2022-03-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural and Mechanistic Insight into CRISPR-Cas9 Inhibition by Anti-CRISPR Protein AcrIIC4 Hpa.
J.Mol.Biol., 434, 2022
6AS4
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BU of 6as4 by Molmil
Structure of a phage anti-CRISPR protein
分子名称: NHis AcrE1 anti-crispr protein
著者Shah, M, Calmettes, C, Pawluk, A, Mejdani, M, Davidson, A.R, Maxwell, K.L, Moraes, T.F.
登録日2017-08-23
公開日2017-12-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein.
MBio, 8, 2017
6AS3
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BU of 6as3 by Molmil
Structure of a phage anti-CRISPR protein
分子名称: NHis AcrE1 protein
著者Shah, M, Calmettes, C, Pawluk, A, Mejdani, M, Davidson, A.R, Maxwell, K.L, Moraes, T.F.
登録日2017-08-23
公開日2018-08-29
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein.
MBio, 8, 2017
4ZA0
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BU of 4za0 by Molmil
Structure of Human Enolase 2 in complex with Phosphonoacetohydroxamate
分子名称: Gamma-enolase, MAGNESIUM ION, PHOSPHONOACETOHYDROXAMIC ACID
著者Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L.
登録日2015-04-13
公開日2016-04-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献SF2312 is a natural phosphonate inhibitor of enolase.
Nat.Chem.Biol., 12, 2016
4ZCW
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BU of 4zcw by Molmil
Structure of Human Enolase 2 in complex with SF2312
分子名称: Gamma-enolase, MAGNESIUM ION, [(3S,5S)-1,5-dihydroxy-2-oxopyrrolidin-3-yl]phosphonic acid
著者Leonard, P.G, Maxwell, D, Czako, B, Muller, F.L.
登録日2015-04-16
公開日2016-07-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献SF2312 is a natural phosphonate inhibitor of enolase.
Nat.Chem.Biol., 12, 2016
5BRL
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BU of 5brl by Molmil
Crystal Structure of L124D STARD4
分子名称: StAR-related lipid transfer protein 4
著者Iaea, D.B, Dikiy, I, Kiburu, I, Eliezer, D.E, Maxfield, F.R.
登録日2015-05-31
公開日2015-07-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献STARD4 Membrane Interactions and Sterol Binding.
Biochemistry, 54, 2015
5W9C
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BU of 5w9c by Molmil
Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S in Complex with 4-hydroxytamoxifen
分子名称: 4-HYDROXYTAMOXIFEN, Estrogen receptor
著者Fanning, S.W, Greene, G.W.
登録日2017-06-23
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
5W9D
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BU of 5w9d by Molmil
Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S Mutant in Complex with Endoxifen
分子名称: Endoxifen, Estrogen receptor
著者Fanning, S.W, Greene, G.L.
登録日2017-06-23
公開日2017-10-11
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.6464 Å)
主引用文献Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
3V9Y
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BU of 3v9y by Molmil
Crystal structure of the PPARgamma-LBD complexed with a cercosporamide derivative modulator
分子名称: 4-{4-[({[(9aS)-8-acetyl-1,7-dihydroxy-3-methoxy-9a-methyl-9-oxo-9,9a-dihydrodibenzo[b,d]furan-4-yl]carbonyl}amino)methyl]naphthalen-2-yl}butanoic acid, Peptide from Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma
著者Matsui, Y, Hanzawa, H.
登録日2011-12-28
公開日2012-02-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPAR(gamma) partial agonists
Bioorg.Med.Chem.Lett., 22, 2012
6CBZ
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BU of 6cbz by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Estradiol and GRIP Peptide
分子名称: ESTRADIOL, Estrogen receptor, GLYCEROL, ...
著者Fanning, S.W, Greene, G.L.
登録日2018-02-05
公開日2018-02-28
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
8JZM
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BU of 8jzm by Molmil
The inhibitor of Toll-like receptor signaling o-vanillin binds covalently to MAL/TIRAP Lys-210
分子名称: Toll/interleukin-1 receptor domain-containing adapter protein
著者Rahaman, M.H, Jia, X, Maxwell, M.J, Mobli, M, Kobe, B.
登録日2023-07-05
公開日2024-05-01
実験手法SOLUTION NMR
主引用文献o-Vanillin binds covalently to MAL/TIRAP Lys-210 but independently inhibits TLR2.
J Enzyme Inhib Med Chem, 39, 2024
5GIP
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BU of 5gip by Molmil
Crystal structure of box C/D RNP with 13 nt guide regions and 11 nt substrates
分子名称: 50S ribosomal protein L7Ae, C/D RNA, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ...
著者Yang, Z, Lin, J, Ye, K.
登録日2016-06-24
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.129 Å)
主引用文献Box C/D guide RNAs recognize a maximum of 10 nt of substrates
Proc.Natl.Acad.Sci.USA, 113, 2016
5GIO
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BU of 5gio by Molmil
Crystal structure of box C/D RNP with 12 nt guide regions and 13 nt substrates
分子名称: 50S ribosomal protein L7Ae, C/D RNA, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ...
著者Yang, Z, Lin, J, Ye, K.
登録日2016-06-24
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.604 Å)
主引用文献Box C/D guide RNAs recognize a maximum of 10 nt of substrates
Proc.Natl.Acad.Sci.USA, 113, 2016
5GIN
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BU of 5gin by Molmil
Crystal structure of box C/D RNP with 12 nt guide regions and 9 nt substrates
分子名称: 50S ribosomal protein L7Ae, C/D RNA, C/D box methylation guide ribonucleoprotein complex aNOP56 subunit, ...
著者Yang, Z, Lin, J, Ye, K.
登録日2016-06-24
公開日2016-09-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.308 Å)
主引用文献Box C/D guide RNAs recognize a maximum of 10 nt of substrates
Proc.Natl.Acad.Sci.USA, 113, 2016
3O85
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Giardia lamblia 15.5kD RNA binding protein
分子名称: Ribosomal protein L7Ae
著者Biswas, S, Maxwell, E.S.
登録日2010-08-02
公開日2011-03-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.806 Å)
主引用文献Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features.
Biochemistry, 50, 2011
3PAF
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M. jannaschii L7Ae mutant
分子名称: 50S ribosomal protein L7Ae, ACETATE ION, SULFATE ION
著者Biswas, S, Maxwell, E.S.
登録日2010-10-19
公開日2011-11-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and stability of M.jannaschii L7Ae El9 KtoQ mutant
To be Published
3T7Z
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Structure of Methanocaldococcus jannaschii Nop N-terminal domain
分子名称: ACETATE ION, GLYCEROL, Nucleolar protein Nop 56/58, ...
著者Biswas, S, Maxwell, S.
登録日2011-07-31
公開日2012-04-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structurally Conserved Nop56/58 N-terminal Domain Facilitates Archaeal Box C/D Ribonucleoprotein-guided Methyltransferase Activity.
J.Biol.Chem., 287, 2012
5NH3
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CRYSTAL STRUCTURE OF THE Activin receptor type-2A LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Activin receptor type-2A, ...
著者Scheufler, C.
登録日2017-03-21
公開日2017-11-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Blockade of activin type II receptors with a dual anti-ActRIIA/IIB antibody is critical to promote maximal skeletal muscle hypertrophy.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017

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