PDB: 5793 件ウェブページステータス検索Chemie searchBIRD

---

3RA3	Crystal structure of a section of a de novo design gigaDalton protein fibre 分子名称: SODIUM ION, p1c, p2f 著者 Zaccai, N.R, Sharp, T.H, Bruning, M, Woolfson, D.N, Brady, R.L. 登録日 2011-03-27 公開日 2012-08-08 最終更新日 2013-06-19 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design Proc.Natl.Acad.Sci.USA, 109, 2012
3UD6	Structural analyses of covalent enzyme-substrate analogue complexes reveal strengths and limitations of de novo enzyme design 分子名称: 1-(6-METHOXYNAPHTHALEN-2-YL)BUTANE-1,3-DIONE, RETRO-ALDOLASE, SULFATE ION 著者 Baker, D, Stoddard, B.L, Althoff, E.A, Wang, L, Jiang, L, Moody, J, Bolduc, J, Lassila, J, Hilvert, D. 登録日 2011-10-27 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.091 Å) 主引用文献 Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. J.Mol.Biol., 415, 2012
3B83	Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. 分子名称: TEN-D3 著者 Hu, X, Ke, H, Kuhlman, B. 登録日 2007-10-31 公開日 2008-11-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. Structure, 16, 2008
9FDG	Solution structure of a de novo designed 12-stranded transmembrane beta-barrel in LDAO micelles. 分子名称: TMB12sol9_3 著者 Muentener, T, Hiller, S. 登録日 2024-05-17 公開日 2024-10-16 実験手法 SOLUTION NMR 主引用文献 Sculpting conducting nanopore size and shape through de novo protein design. Science, 385, 2024
6XXV	Crystal Structure of a computationally designed Immunogen S2_1.2 in complex with its elicited antibody C57 分子名称: Antibody C57, Heavy Chain, Light Chain, ... 著者 Yang, C, Sesterhenn, F, Correia, B.E, Pojer, F. 登録日 2020-01-28 公開日 2020-04-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.20116425 Å) 主引用文献 De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, 368, 2020
8ETQ	Designed pentafoil knot protein folded into a trefoil knot 分子名称: k-cTRP5 著者 Doyle, L.A, Kibler, R.D, Bradley, P, Stoddard, B.L. 登録日 2022-10-17 公開日 2023-10-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.42 Å) 主引用文献 De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
7SQ4	Designed trefoil knot protein, variant 2 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Designed trefoil knot protein, variant 2, ... 著者 Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. 登録日 2021-11-04 公開日 2022-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.493 Å) 主引用文献 De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
7SQ3	Designed trefoil knot protein, variant 1 分子名称: CHLORIDE ION, Designed trefoil knot protein, variant 1, ... 著者 Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. 登録日 2021-11-04 公開日 2022-06-29 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.453 Å) 主引用文献 De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
7SQ5	Designed trefoil knot protein, variant 3 分子名称: Designed trefoil knot protein, variant 3, SODIUM ION 著者 Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. 登録日 2021-11-04 公開日 2022-11-09 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.205 Å) 主引用文献 De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
8Y9B	TcdB1 in complex with mini-binder 分子名称: De novo design mini-binder, Toxin B, ZINC ION 著者 Lv, X.C, Lu, P.L. 登録日 2024-02-06 公開日 2024-08-28 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 De novo design of mini-protein binders broadly neutralizing Clostridioides difficile toxin B variants. Nat Commun, 15, 2024
9IZ6	De Novo Designed Cell-Penetrating Peptide Self-Assembly Featuring Distinctive Tertiary Structure 分子名称: GLYCEROL, LEU-LYS-LYS-LEU-CYS-LYS-LEU-LEU-LYS-LYS-LEU-CYS-LYS-LEU-ALA-GLY 著者 Park, J, Hyun, S, Lee, S.J. 登録日 2024-07-31 公開日 2024-09-11 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 De Novo Designed Cell-Penetrating Peptide Self-Assembly Featuring Distinctive Tertiary Structure. Acs Omega, 9, 2024
9J7T	De Novo Designed Cell-Penetrating Peptide Self-Assembly Featuring Distinctive Tertiary Structure 分子名称: GLYCEROL, LKa14 著者 Park, J, Hyun, S, Lee, S.J. 登録日 2024-08-19 公開日 2024-09-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 De Novo Designed Cell-Penetrating Peptide Self-Assembly Featuring Distinctive Tertiary Structure Acs Omega, 9, 2024
8SRN	De novo designed transmembrane antiparallel homo-dimer G-X6-G 01322-42 分子名称: Gx6G_denovo_design_01322-42 著者 Golden, J, Dai, X, Mravic, M. 登録日 2023-05-05 公開日 2024-09-04 実験手法 X-RAY DIFFRACTION (3.275 Å) 主引用文献 De Novo Design Reveals Principles of a Common Membrane Protein Structural Building Block: The G-X6-G Motif To Be Published
5F72	De novo design and crystallographic validation of antibodies targeting a pre-selected epitope 分子名称: Kelch-like ECH-associated protein 1, Single chain Fv from a Fab 著者 Liu, X, Taylor, R.D, Griffin, L, Coker, S, Adams, R, Ceska, T, Shi, J, Lawson, A.D.G, Baker, T. 登録日 2015-12-07 公開日 2016-12-14 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 De novo design and crystallographic validation of antibodies targeting a pre-selected epitope To Be Published
6S3D	Structure of D25 Fab in complex with scaffold S0_2.126 分子名称: Heavy Chain, Light Chain, S0_2.126 著者 Cramer, J.T, Krey, T. 登録日 2019-06-25 公開日 2020-04-22 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, 368, 2020
5J0H	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: Design construct 2L6HC3_13 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. 登録日 2016-03-28 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5J10	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: peptide design 2L4HC2_24 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. 登録日 2016-03-28 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5J73	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: protein design 2L4HC2_9 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. 登録日 2016-04-05 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5J2L	De novo design of protein homo-oligomers with modular hydrogen bond network-mediated specificity 分子名称: protein design 2L4HC2_11 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Boyken, S, Chen, Z, Groves, B, Langan, R.A, Oberdorfer, G, Ford, A, Gilmore, J, Xu, C, DiMaio, F, Seelig, G. 登録日 2016-03-29 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
5JQZ	Designed two-ring homotetramer at 3.8A resolution 分子名称: De novo designed homotetramer 著者 Sankaran, B, Zwart, P.H, Pereira, J.H, Baker, D, Oberdorfer, G, Boyken, S.E, Chen, Z. 登録日 2016-05-05 公開日 2016-06-29 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.83 Å) 主引用文献 De novo design of protein homo-oligomers with modular hydrogen-bond network-mediated specificity. Science, 352, 2016
8OYV	De novo designed Claudin fold CLF_4 分子名称: De novo designed soluble Claudin 著者 Pacesa, M, Correia, B.E. 登録日 2023-05-05 公開日 2023-10-18 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Computational design of soluble and functional membrane protein analogues. Nature, 631, 2024
8OYX	De novo designed soluble GPCR-like fold GLF_18 分子名称: De novo designed soluble GPCR-like protein, PHOSPHATE ION 著者 Pacesa, M, Correia, B.E. 登録日 2023-05-05 公開日 2023-10-18 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Computational design of soluble and functional membrane protein analogues. Nature, 631, 2024
8OYW	De novo designed rhomboid protease-like fold RPF_9 分子名称: De novo designed soluble Rhomboid protease-like protein, SODIUM ION 著者 Pacesa, M, Correia, B.E. 登録日 2023-05-05 公開日 2023-10-18 最終更新日 2024-08-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Computational design of soluble and functional membrane protein analogues. Nature, 631, 2024
8GL3	De novo design of monomeric helical bundles for pH-controlled membrane lysis 分子名称: pRLB-519 著者 Goldbach, N, Bera, A.K, Baker, D, Kang, A. 登録日 2023-03-20 公開日 2023-09-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 De novo design of monomeric helical bundles for pH-controlled membrane lysis. Protein Sci., 32, 2023
8FLX	De novo designed homotrimer; the fusion product of BGL17 and DHR59 分子名称: LK031 著者 Kibler, R.D, Kennedy, M.A, Stoddard, B.L, Lee, S. 登録日 2022-12-22 公開日 2023-06-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 De novo designed homotrimer; the fusion product of BGL17 and DHR59 To Be Published

<45678910111213141516171819>