8G6J
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![BU of 8g6j by Molmil](/molmil-images/mine/8g6j) | mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2) | 分子名称: | (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-15 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8G85
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![BU of 8g85 by Molmil](/molmil-images/mine/8g85) | vFP52.02 Fab in complex with BG505 DS-SOSIP Env trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Gorman, J, Kwong, P.D. | 登録日 | 2023-02-17 | 公開日 | 2023-04-19 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (3.99 Å) | 主引用文献 | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization. J.Virol., 97, 2023
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8G9B
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![BU of 8g9b by Molmil](/molmil-images/mine/8g9b) | Human IMPDH2 mutant - L245P, treated with GTP, ATP, IMP, and NAD+; compressed filament segment reconstruction | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | 著者 | O'Neill, A.G, Kollman, J.M. | 登録日 | 2023-02-21 | 公開日 | 2023-04-19 | 最終更新日 | 2023-08-09 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation. J.Biol.Chem., 299, 2023
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8GLP
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![BU of 8glp by Molmil](/molmil-images/mine/8glp) | mRNA decoding in human is kinetically and structurally distinct from bacteria (Consensus LSU focused refined structure) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Watson, Z.L, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-03-22 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (1.67 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8G60
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![BU of 8g60 by Molmil](/molmil-images/mine/8g60) | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8GAS
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![BU of 8gas by Molmil](/molmil-images/mine/8gas) | vFP48.02 Fab in complex with BG505 DS-SOSIP Env trimer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | 著者 | Gorman, J, Kwong, P.D. | 登録日 | 2023-02-23 | 公開日 | 2023-04-19 | 最終更新日 | 2023-06-14 | 実験手法 | ELECTRON MICROSCOPY (4.04 Å) | 主引用文献 | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization. J.Virol., 97, 2023
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8GHU
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![BU of 8ghu by Molmil](/molmil-images/mine/8ghu) | |
8FL6
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![BU of 8fl6 by Molmil](/molmil-images/mine/8fl6) | |
7RLJ
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![BU of 7rlj by Molmil](/molmil-images/mine/7rlj) | Cryo-EM structure of human p97 bound to CB-5083 and ATPgS. | 分子名称: | 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. | 登録日 | 2021-07-23 | 公開日 | 2021-09-22 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
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8EIU
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![BU of 8eiu by Molmil](/molmil-images/mine/8eiu) | E. coli 70S ribosome with A-loop mutations U2554C and U2555C | 分子名称: | 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | 著者 | Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D. | 登録日 | 2022-09-15 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.24 Å) | 主引用文献 | Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome. Nucleic Acids Res., 51, 2023
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7RSC
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![BU of 7rsc by Molmil](/molmil-images/mine/7rsc) | NMR-driven structure of the KRAS4B-G12D "alpha-alpha" dimer on a lipid bilayer nanodisc | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Apolipoprotein A-I, GTPase KRas, ... | 著者 | Lee, K, Enomoto, M, Gebregiworgis, T, Gasmi-Seabrook, G.M, Ikura, M, Marshall, C.B. | 登録日 | 2021-08-11 | 公開日 | 2021-09-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization. Chem Sci, 12, 2021
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8FC6
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![BU of 8fc6 by Molmil](/molmil-images/mine/8fc6) | Crystal structure of the A2058-N6-dimethylated Thermus thermophilus 70S ribosome in complex with protein Y, hygromycin A, and telithromycin at 2.35A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Chen, C.-W, Syroegin, E.A, Svetlov, M.S, Polikanov, Y.S. | 登録日 | 2022-12-01 | 公開日 | 2023-07-26 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A. Nat Commun, 14, 2023
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7RKV
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![BU of 7rkv by Molmil](/molmil-images/mine/7rkv) | Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C118 Fab Heavy Chain, C118 Fab Light Chain, ... | 著者 | Barnes, C.O, Jette, C.A, Bjorkman, P.J. | 登録日 | 2021-07-22 | 公開日 | 2021-09-22 | 最終更新日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies. Cell Rep, 36, 2021
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8FLC
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![BU of 8flc by Molmil](/molmil-images/mine/8flc) | |
7RSE
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![BU of 7rse by Molmil](/molmil-images/mine/7rse) | NMR-driven structure of the KRAS4B-G12D "alpha-beta" dimer on a lipid bilayer nanodisc | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Apolipoprotein A-I, GTPase KRas, ... | 著者 | Lee, K, Enomoto, M, Gebregiworgis, T, Gasmi-Seabrook, G.M, Ikura, M, Marshall, C.B. | 登録日 | 2021-08-11 | 公開日 | 2021-09-22 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization. Chem Sci, 12, 2021
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8FTO
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![BU of 8fto by Molmil](/molmil-images/mine/8fto) | |
8FLD
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![BU of 8fld by Molmil](/molmil-images/mine/8fld) | |
1CJL
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![BU of 1cjl by Molmil](/molmil-images/mine/1cjl) | |
8T8B
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![BU of 8t8b by Molmil](/molmil-images/mine/8t8b) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site formyl-MAI-tripeptidyl-tRNA analog ACCA-IAMf at 2.65A resolution | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | 著者 | Thaler, J, Syroegin, E.A, Breuker, K, Polikanov, Y.S, Micura, R. | 登録日 | 2023-06-22 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Practical Synthesis of N -Formylmethionylated Peptidyl-tRNA Mimics. Acs Chem.Biol., 18, 2023
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5E6P
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![BU of 5e6p by Molmil](/molmil-images/mine/5e6p) | |
5DU1
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![BU of 5du1 by Molmil](/molmil-images/mine/5du1) | Crystal structure of Dendroaspis polylepis mambalgin-1 wild-type in P21 space group. | 分子名称: | Mambalgin-1 | 著者 | Stura, E.A, Tepshi, L, Mourier, G, Kessler, P, Servent, D. | 登録日 | 2015-09-18 | 公開日 | 2015-12-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition. J.Biol.Chem., 291, 2016
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7Q0P
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![BU of 7q0p by Molmil](/molmil-images/mine/7q0p) | Structure of the Candida albicans 80S ribosome in complex with anisomycin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | 著者 | Kolosova, O, Zgadzay, Y, Stetsenko, A, Jenner, L, Guskov, A, Yusupova, G, Yusupov, M. | 登録日 | 2021-10-15 | 公開日 | 2022-05-18 | 最終更新日 | 2022-06-08 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | E-site drug specificity of the human pathogen Candida albicans ribosome. Sci Adv, 8, 2022
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7PIC
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![BU of 7pic by Molmil](/molmil-images/mine/7pic) | 70S ribosome with P/E-site tRNA in spectinomycin-treated Mycoplasma pneumoniae cells | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | 登録日 | 2021-08-19 | 公開日 | 2022-05-25 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (9.1 Å) | 主引用文献 | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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7PI8
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![BU of 7pi8 by Molmil](/molmil-images/mine/7pi8) | 70S ribosome with P-site tRNA in spectinomycin-treated Mycoplasma pneumoniae cells | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | 登録日 | 2021-08-19 | 公開日 | 2022-05-25 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | 主引用文献 | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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7PIA
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![BU of 7pia by Molmil](/molmil-images/mine/7pia) | 70S ribosome with A/P- and P/E-site tRNAs in spectinomycin-treated Mycoplasma pneumoniae cells | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | 登録日 | 2021-08-19 | 公開日 | 2022-05-25 | 最終更新日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (13.6 Å) | 主引用文献 | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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