1CL3
 
 | | MOLECULAR INSIGHTS INTO PEBP2/CBF-SMMHC ASSOCIATED ACUTE LEUKEMIA REVEALED FROM THE THREE-DIMENSIONAL STRUCTURE OF PEBP2/CBF BETA | | 分子名称: | POLYOMAVIRUS ENHANCER BINDING PROTEIN 2 | | 著者 | Goger, M, Gupta, V, Kim, W.Y, Shigesada, K, Ito, Y, Werner, M.H. | | 登録日 | 1999-05-04 | | 公開日 | 2000-01-01 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Molecular insights into PEBP2/CBF beta-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBF beta
Nat.Struct.Biol., 6, 1999
|
|
1JLA
 | | CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH TNK-651 | | 分子名称: | 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL, HIV-1 RT A-chain, HIV-1 RT B-chain | | 著者 | Ren, J, Nichols, C, Bird, L, Chamberlain, P, Weaver, K, Short, S, Stuart, D.I, Stammers, D.K. | | 登録日 | 2001-07-16 | | 公開日 | 2001-10-03 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
J.Mol.Biol., 312, 2001
|
|
1JLE
 | | CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE | | 分子名称: | HIV-1 RT, A-CHAIN, B-CHAIN | | 著者 | Ren, J, Nichols, C, Bird, L, Chamberlain, P, Weaver, K, Short, S, Stuart, D.I, Stammers, D.K. | | 登録日 | 2001-07-16 | | 公開日 | 2001-10-03 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
J.Mol.Biol., 312, 2001
|
|
1JKH
 | | CRYSTAL STRUCTURE OF Y181C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH DMP-266(EFAVIRENZ) | | 分子名称: | (-)-6-CHLORO-4-CYCLOPROPYLETHYNYL-4-TRIFLUOROMETHYL-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE, HIV-1 RT, A-CHAIN, ... | | 著者 | Ren, J, Nichols, C, Bird, L, Chamberlain, P, Weaver, K, Short, S, Stuart, D.I, Stammers, D.K. | | 登録日 | 2001-07-12 | | 公開日 | 2001-10-03 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
J.Mol.Biol., 312, 2001
|
|
1JLG
 | | CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH UC-781 | | 分子名称: | 2-METHYL-FURAN-3-CARBOTHIOIC ACID [4-CHLORO-3-(3-METHYL-BUT-2-ENYLOXY)-PHENYL]-AMIDE, HIV-1 RT A-chain, HIV-1 RT B-chain | | 著者 | Ren, J, Nichols, C, Bird, L, Chamberlain, P, Weaver, K, Short, S, Stuart, D.I, Stammers, D.K. | | 登録日 | 2001-07-16 | | 公開日 | 2001-10-03 | | 最終更新日 | 2022-12-21 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural mechanisms of drug resistance for mutations at codons 181 and 188 in HIV-1 reverse transcriptase and the improved resilience of second generation non-nucleoside inhibitors.
J.Mol.Biol., 312, 2001
|
|
1U36
 | | Crystal structure of WLAC mutant of dimerisation domain of NF-kB p50 transcription factor | | 分子名称: | Nuclear factor NF-kappa-B p105 subunit | | 著者 | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | 登録日 | 2004-07-21 | | 公開日 | 2004-08-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
|
|
6Z6F
 | | HDAC-PC | | 分子名称: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | | 著者 | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | | 登録日 | 2020-05-28 | | 公開日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | | 主引用文献 | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
|
|
2DB7
 | | Crystal structure of hypothetical protein MS0332 | | 分子名称: | Hairy/enhancer-of-split related with YRPW motif 1 | | 著者 | Wang, H, Takemoto-Hori, C, Murayama, K, Terada, T, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-12-15 | | 公開日 | 2006-12-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of hypothetical protein MS0332
To be Published
|
|
6Z6O
 | | HDAC-TC | | 分子名称: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | | 著者 | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | | 登録日 | 2020-05-28 | | 公開日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
|
|
6Z6H
 | | HDAC-DC | | 分子名称: | HDA1 complex subunit 2, HDA1 complex subunit 3,HDA1 complex subunit 3, Histone deacetylase HDA1, ... | | 著者 | Lee, J.-H, Bollschweiler, D, Schaefer, T, Huber, R. | | 登録日 | 2020-05-28 | | 公開日 | 2021-02-17 | | 実験手法 | ELECTRON MICROSCOPY (8.55 Å) | | 主引用文献 | Structural basis for the regulation of nucleosome recognition and HDAC activity by histone deacetylase assemblies.
Sci Adv, 7, 2021
|
|
5ICK
 | | A unique binding model of FXR LBD with feroline | | 分子名称: | (1S,2S,3Z,5S,8Z)-5-hydroxy-5,9-dimethyl-2-(propan-2-yl)cyclodeca-3,8-dien-1-yl 4-hydroxybenzoate, Bile acid receptor, Nuclear receptor coactivator 2 | | 著者 | Lu, Y, Li, Y. | | 登録日 | 2016-02-23 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | A Novel Class of Natural FXR Modulators with a Unique Mode of Selective Co-regulator Assembly
Chembiochem, 18, 2017
|
|
6DMA
 | | DHD15_closed | | 分子名称: | DHD15_closed_A, DHD15_closed_B | | 著者 | Bick, M.J, Chen, Z, Baker, D. | | 登録日 | 2018-06-04 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.363 Å) | | 主引用文献 | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
|
|
4ES0
 | | X-ray structure of WDR5-SETd1b Win motif peptide binary complex | | 分子名称: | Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5 | | 著者 | Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S. | | 登録日 | 2012-04-21 | | 公開日 | 2012-05-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.817 Å) | | 主引用文献 | Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
|
|
3WKV
 | | Voltage-gated proton channel: VSOP/Hv1 chimeric channel | | 分子名称: | Ion channel | | 著者 | Takeshita, K, Sakata, S, Yamashita, E, Fujiwara, Y, Kawanabe, A, Kurokawa, T, Okochi, Y, Matsuda, M, Narita, H, Okamura, Y, Nakagawa, A. | | 登録日 | 2013-10-31 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.453 Å) | | 主引用文献 | X-ray crystal structure of voltage-gated proton channel.
Nat.Struct.Mol.Biol., 21, 2014
|
|
5IJN
 | | Composite structure of the inner ring of the human nuclear pore complex (32 copies of Nup205) | | 分子名称: | NUCLEAR PORE COMPLEX PROTEIN NUP155, NUCLEAR PORE COMPLEX PROTEIN NUP205, NUCLEAR PORE COMPLEX PROTEIN NUP54, ... | | 著者 | Kosinski, J, Mosalaganti, S, von Appen, A, Beck, M. | | 登録日 | 2016-03-02 | | 公開日 | 2016-04-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (21.4 Å) | | 主引用文献 | Molecular architecture of the inner ring scaffold of the human nuclear pore complex.
Science, 352, 2016
|
|
6O3H
 | | Icosahedral reconstruction of the thermophilic bacteriophage P74-26 capsid | | 分子名称: | Major head protein, P74-26 Head Decoration Protein | | 著者 | Stone, N.P, Demo, G, Agnello, E, Kelch, B.A. | | 登録日 | 2019-02-26 | | 公開日 | 2019-07-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Principles for enhancing virus capsid capacity and stability from a thermophilic virus capsid structure.
Nat Commun, 10, 2019
|
|
1U41
 | | Crystal structure of YLGV mutant of dimerisation domain of NF-kB p50 transcription factor | | 分子名称: | Nuclear factor NF-kappa-B p105 subunit | | 著者 | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | 登録日 | 2004-07-23 | | 公開日 | 2004-08-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
|
|
4X1F
 | | Crystal structure of the hPXR-LBD in complex with the synthetic estrogen 17alpha-ethinylestradiol | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Ethinyl estradiol, Nuclear receptor subfamily 1 group I member 2 | | 著者 | Delfosse, V, Huet, T, Bourguet, W. | | 登録日 | 2014-11-24 | | 公開日 | 2015-09-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Synergistic activation of human pregnane X receptor by binary cocktails of pharmaceutical and environmental compounds.
Nat Commun, 6, 2015
|
|
4MEH
 | |
6DKM
 | | DHD131 | | 分子名称: | DHD131_A, DHD131_B | | 著者 | Bick, M.J, Chen, Z, Baker, D. | | 登録日 | 2018-05-29 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | | 主引用文献 | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
|
|
7SQB
 | | PPAR gamma LBD bound to Inverse Agonist SR10221 | | 分子名称: | (2S)-2-{5-[(5-{[(1S)-1-(4-tert-butylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}propanoic acid, Peroxisome proliferator-activated receptor gamma | | 著者 | Frkic, R.L, Pederick, J.L, Bruning, J.B. | | 登録日 | 2021-11-05 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | PPAR gamma Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles.
Acs Chem.Biol., 18, 2023
|
|
7SQA
 | | PPAR gamma LBD bound to SR10221 and SMRT corepressor motif | | 分子名称: | (2S)-2-{5-[(5-{[(1S)-1-(4-tert-butylphenyl)ethyl]carbamoyl}-2,3-dimethyl-1H-indol-1-yl)methyl]-2-chlorophenoxy}propanoic acid, Nuclear receptor corepressor 2, Peroxisome proliferator-activated receptor gamma | | 著者 | Frkic, R.L, Pederick, J.L, Bruning, J.B. | | 登録日 | 2021-11-05 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | | 主引用文献 | PPAR gamma Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles.
Acs Chem.Biol., 18, 2023
|
|
1U3Y
 | | Crystal structure of ILAC mutant of dimerisation domain of NF-kB p50 transcription factor | | 分子名称: | Nuclear factor NF-kappa-B p105 subunit | | 著者 | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | 登録日 | 2004-07-22 | | 公開日 | 2004-08-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
|
|
1U42
 | | Crystal structure of MLAM mutant of dimerisation domain of NF-kB p50 transcription factor | | 分子名称: | Nuclear factor NF-kappa-B p105 subunit | | 著者 | Chirgadze, D.Y, Demydchuk, M, Becker, M, Moran, S, Paoli, M. | | 登録日 | 2004-07-23 | | 公開日 | 2004-08-17 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.699 Å) | | 主引用文献 | Snapshot of Protein Structure Evolution Reveals Conservation of Functional Dimerization through Intertwined Folding
Structure, 12, 2004
|
|
6DM9
 | | DHD15_extended | | 分子名称: | DHD15_extended_A, DHD15_extended_B, SULFATE ION | | 著者 | Bick, M.J, Chen, Z, Baker, D. | | 登録日 | 2018-06-04 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Programmable design of orthogonal protein heterodimers.
Nature, 565, 2019
|
|
