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2ALZ
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Ternary Complex of hPoli with DNA and dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*GP*GP*GP*GP*TP*CP*CP*T)-3', ...
著者Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K.
登録日2005-08-08
公開日2005-10-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human DNA Polymerase iota Incorporates dCTP Opposite Template G via a G.C+ Hoogsteen Base Pair.
Structure, 13, 2005
4DQR
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BU of 4dqr by Molmil
Ternary complex of Bacillus DNA Polymerase I Large Fragment E658A, DNA duplex, and rCTP (paired with dG of template) in presence of Mn2+
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), ...
著者Wang, W, Beese, L.S.
登録日2012-02-16
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
2VDW
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BU of 2vdw by Molmil
Guanosine N7 methyl-transferase sub-complex (D1-D12) of the vaccinia virus mRNA capping enzyme
分子名称: MRNA-CAPPING ENZYME SMALL SUBUNIT, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
著者De la Pena, M, Kyrieleis, O.J.P, Cusack, S.
登録日2007-10-12
公開日2008-05-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural Insights Into the Mechanism and Evolution of the Vaccinia Virus Mrna CAP N7 Methyl- Transferase.
Embo J., 26, 2007
2LSN
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BU of 2lsn by Molmil
Solution structure of PFV RNase H domain
分子名称: RNase H
著者Leo, B, Schweimer, K, Woehrl, B.
登録日2012-05-03
公開日2012-10-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding.
Retrovirology, 9, 2012
2M24
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BU of 2m24 by Molmil
NMR solution structure of the d3'-hairpin including the exon binding site 1 (EBS1) of the group II intron Sc.ai5gamma
分子名称: RNA (29-MER)
著者Kruschel, D, Skilandat, M, Sigel, R.K.O.
登録日2012-12-12
公開日2013-12-18
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献NMR structure of the 5' splice site in the group IIB intron Sc.ai5 gamma--conformational requirements for exon-intron recognition.
Rna, 20, 2014
6N2S
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BU of 6n2s by Molmil
Ternary complex crystal structure of DNA polymerase Beta with 5-carboxy-dC (5-caC) at the templating position
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(1CC)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2018-11-14
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.457 Å)
主引用文献Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA polymerase beta.
J.Biol.Chem., 294, 2019
6N2T
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BU of 6n2t by Molmil
Ternary complex crystal structure of DNA polymerase Beta with 5-hydroxymethyl-dC (5-hmC) at the templating position
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(5HC)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), ...
著者Batra, V.K, Wilson, S.H.
登録日2018-11-14
公開日2019-03-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis for the faithful replication of 5-methylcytosine and its oxidized forms by DNA polymerase beta.
J.Biol.Chem., 294, 2019
4JWN
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BU of 4jwn by Molmil
Ternary complex of D256A mutant of DNA Polymerase Beta
分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ...
著者Batra, V.K, Perera, L, Ping, L, Shock, D.D, Beard, W.A, Pedersen, L.C, Pedersen, L.G, Wilson, S.H.
登録日2013-03-27
公開日2013-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Amino Acid Substitution in the Active Site of DNA Polymerase beta Explains the Energy Barrier of the Nucleotidyl Transfer Reaction.
J.Am.Chem.Soc., 135, 2013
3CQ8
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BU of 3cq8 by Molmil
Ternary complex of the L415F mutant RB69 exo(-)polymerase
分子名称: CALCIUM ION, DNA (5'-D(*DAP*DCP*DAP*DGP*DGP*DTP*DAP*DAP*DGP*DCP*DAP*DGP*DTP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(*DGP*DCP*DGP*DGP*DAP*DCP*DTP*DGP*DCP*DTP*DTP*DAP*DCP*DC)-3'), ...
著者Zhong, X, Pedersen, L.C, Kunkel, T.A.
登録日2008-04-02
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity.
Nucleic Acids Res., 36, 2008
1SC5
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BU of 1sc5 by Molmil
Sigma-28(FliA)/FlgM complex
分子名称: RNA polymerase sigma factor FliA, anti-sigma factor FlgM
著者Sorenson, M.K, Ray, S.S, Darst, S.A.
登録日2004-02-11
公開日2004-04-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation.
Mol.Cell, 14, 2004
1H3L
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BU of 1h3l by Molmil
N-terminal fragment of SigR from Streptomyces coelicolor
分子名称: RNA POLYMERASE SIGMA FACTOR
著者Li, W, Stevenson, C.E.M, Burton, N, Jakimowicz, P, Paget, M.S.B, Buttner, M.J, Lawson, D.M, Kleanthous, C.
登録日2002-09-10
公開日2002-10-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.375 Å)
主引用文献Identification and Structure of the Anti-Sigma Factor-Binding Domain of the Disulfide-Stress Regulated Sigma Factor Sigma(R) from Streptomyces Coelicolor
J.Mol.Biol., 323, 2002
3MGI
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BU of 3mgi by Molmil
Ternary complex of a DNA polymerase lambda loop mutant
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA, DNA (5'-D(*CP*AP*GP*TP*AP*T)-3'), ...
著者Garcia-Diaz, M, Bebenek, K, Zhou, R.Z, Povirk, L.F, Kunkel, T.
登録日2010-04-06
公開日2010-05-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.603 Å)
主引用文献Loop 1 modulates the fidelity of DNA polymerase lambda
Nucleic Acids Res., 38, 2010
4DOB
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BU of 4dob by Molmil
Ternary complex of DNA polymerase beta with a dideoxy terminated primer and 2'-deoxyguanosine 5'-beta, gamma-monochlororomethylene triphosphate: Stereoselective binding of R-isomer
分子名称: 5'-O-[(R)-{[(R)-[(R)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxyguanosine, C C G A C C G C G C A T C A G C, CHLORIDE ION, ...
著者Batra, V.K.
登録日2012-02-09
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Beta,Gamma-CHF- and beta,gamma-CHCl-dGTP Diastereomers: Synthesis, Discrete (31)P NMR Signatures, and Absolute Configurations of New Stereochemical Probes for DNA Polymerases
J.Am.Chem.Soc., 134, 2012
2M2W
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BU of 2m2w by Molmil
Ternary complex of ASFV Pol X with DNA and MgdGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(P*GP*GP*CP*GP*AP*AP*GP*CP*CP*GP*GP*GP*TP*GP*CP*GP*AP*AP*GP*CP*AP*CP*(DOC))-3', MAGNESIUM ION, ...
著者Wu, W, Su, M, Tsai, M.
登録日2013-01-03
公開日2014-04-02
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation.
J.Am.Chem.Soc., 136, 2014
3P1G
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BU of 3p1g by Molmil
Crystal Structure of the Xenotropic Murine Leukemia Virus-Related Virus (XMRV) RNase H Domain
分子名称: MAGNESIUM ION, Xenotropic Murine Leukemia Virus-Related Virus (XMRV) RNase H Domain
著者Kirby, K.A, Sarafianos, S.G.
登録日2010-09-30
公開日2010-10-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase.
Antimicrob.Agents Chemother., 56, 2012
1RP3
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BU of 1rp3 by Molmil
Cocrystal structure of the flagellar sigma/anti-sigma complex, Sigma-28/FlgM
分子名称: RNA polymerase sigma factor SIGMA-28 (FliA), anti sigma factor FlgM
著者Sorenson, M.K, Ray, S.S, Darst, S.A.
登録日2003-12-02
公開日2004-04-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Flagellar Sigma/Anti-Sigma Complex Sigma(28)/FlgM Reveals an Intact Sigma Factor in an Inactive Conformation
Mol.Cell, 14, 2004
1G5I
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BU of 1g5i by Molmil
CRYSTAL STRUCTURE OF THE ACCESSORY SUBUNIT OF MURINE MITOCHONDRIAL POLYMERASE GAMMA
分子名称: GLYCEROL, MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT, SODIUM ION
著者Carrodeguas, J.A, Theis, K, Bogenhagen, D.F, Kisker, C.
登録日2000-11-01
公開日2001-03-14
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer.
Mol.Cell, 7, 2001
1G5H
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BU of 1g5h by Molmil
CRYSTAL STRUCTURE OF THE ACCESSORY SUBUNIT OF MURINE MITOCHONDRIAL POLYMERASE GAMMA
分子名称: GLYCEROL, MITOCHONDRIAL DNA POLYMERASE ACCESSORY SUBUNIT, SODIUM ION
著者Carrodeguas, J.A, Theis, K, Bogenhagen, D.F, Kisker, C.
登録日2000-11-01
公開日2001-03-14
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure and deletion analysis show that the accessory subunit of mammalian DNA polymerase gamma, Pol gamma B, functions as a homodimer.
Mol.Cell, 7, 2001
1O4X
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BU of 1o4x by Molmil
TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE HOXB1 REGULATORY ELEMENT
分子名称: 5'-D(*CP*AP*TP*TP*AP*GP*CP*AP*TP*GP*AP*CP*AP*AP*AP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*TP*TP*TP*GP*TP*CP*AP*TP*GP*CP*TP*AP*AP*TP*G)-3', Transcription factor SOX-2, ...
著者Clore, G.M, Williams, D.C.
登録日2003-07-17
公開日2004-01-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Molecular basis for synergistic transcriptional activation by Oct1 and Sox2 revealed from the solution structure of the 42-kDa Oct1.Sox2.Hoxb1-DNA ternary transcription factor complex.
J.Biol.Chem., 279, 2004
3IAY
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BU of 3iay by Molmil
Ternary complex of DNA polymerase delta
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ...
著者Swan, M.K, Aggarwal, A.K.
登録日2009-07-15
公開日2009-09-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta
Nat.Struct.Mol.Biol., 16, 2009
1SL2
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BU of 1sl2 by Molmil
Ternary 5' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template and an incoming nucleotide
分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*TP*(2DA))-3', ...
著者Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T.
登録日2004-03-05
公開日2004-07-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
1SL0
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BU of 1sl0 by Molmil
Ternary 3' complex of T7 DNA polymerase with a DNA primer/template containing a disordered cis-syn thymine dimer on the template and an incoming nucleotide
分子名称: 2',3'-DIDEOXYADENOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*CP*(TTD)P*AP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3', ...
著者Li, Y, Dutta, S, Doublie, S, Bdour, H.M, Taylor, J.S, Ellenberger, T.
登録日2004-03-05
公開日2004-07-06
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Nucleotide insertion opposite a cis-syn thymine dimer by a replicative DNA polymerase from bacteriophage T7.
Nat.Struct.Mol.Biol., 11, 2004
4DQQ
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Ternary complex of Bacillus DNA Polymerase I Large Fragment E658A, DNA duplex, and rCTP (paired with dG of template) in presence of Mg2+
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Wang, W, Beese, L.S.
登録日2012-02-16
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.595 Å)
主引用文献Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
4DSF
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BU of 4dsf by Molmil
Ternary complex of Bacillus DNA Polymerase I Large Fragment F710Y, DNA duplex, and rCTP (paired with dG of template) in presence of Mn2+
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*AP*TP*GP*GP*GP*AP*GP*TP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*AP*CP*TP*CP*(DOC))-3'), ...
著者Wang, W, Beese, L.S.
登録日2012-02-18
公開日2012-06-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.661 Å)
主引用文献Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides.
J.Biol.Chem., 287, 2012
2DPI
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Ternary complex of hPoli with DNA and dCTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', ...
著者Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K.
登録日2006-05-12
公開日2006-07-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota.
Nat.Struct.Mol.Biol., 13, 2006

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