5M9S
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![BU of 5m9s by Molmil](/molmil-images/mine/5m9s) | Human angiogenin ALS variant V103I | 分子名称: | Angiogenin, D(-)-TARTARIC ACID | 著者 | Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R. | 登録日 | 2016-11-02 | 公開日 | 2017-02-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Sci Rep, 7, 2017
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6SI9
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![BU of 6si9 by Molmil](/molmil-images/mine/6si9) | FtsZ-refold | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cell division protein FtsZ, ... | 著者 | Fernandez-Tornero, C, Andreu, J.M, Ruiz, F.M. | 登録日 | 2019-08-09 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus. Febs J., 287, 2020
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5MAM
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![BU of 5mam by Molmil](/molmil-images/mine/5mam) | Human insulin in complex with serotonin | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | 著者 | Brzozowski, A.M, Turkenburg, J.P, Jiracek, J, Zakova, L. | 登録日 | 2016-11-03 | 公開日 | 2017-04-05 | 最終更新日 | 2017-05-31 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Computational and structural evidence for neurotransmitter-mediated modulation of the oligomeric states of human insulin in storage granules. J. Biol. Chem., 292, 2017
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6SOR
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5MCI
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![BU of 5mci by Molmil](/molmil-images/mine/5mci) | Radiation damage to GH7 Family Cellobiohydrolase from Daphnia pulex: Dose (DWD) 11.9 MGy | 分子名称: | Cellobiohydrolase CHBI, GLYCEROL, SULFATE ION | 著者 | Bury, C.S, McGeehan, J.E, Ebrahim, A, Garman, E.F. | 登録日 | 2016-11-09 | 公開日 | 2017-01-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | OH cleavage from tyrosine: debunking a myth. J Synchrotron Radiat, 24, 2017
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7B1I
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7B2R
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6SHI
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![BU of 6shi by Molmil](/molmil-images/mine/6shi) | |
7B36
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![BU of 7b36 by Molmil](/molmil-images/mine/7b36) | MST4 in complex with compound G-5555 | 分子名称: | 1,2-ETHANEDIOL, 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one, CHLORIDE ION, ... | 著者 | Tesch, R, Rak, M, Joerger, A.C, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-11-28 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.10681081 Å) | 主引用文献 | Structure-Based Design of Selective Salt-Inducible Kinase Inhibitors. J.Med.Chem., 64, 2021
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5M7F
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![BU of 5m7f by Molmil](/molmil-images/mine/5m7f) | Human porphobilinogen deaminase in complex with DPM cofactor | 分子名称: | 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, Porphobilinogen deaminase, SULFATE ION | 著者 | Pluta, P, Millet, O, Roversi, P, Rojas, A.L, Gu, S. | 登録日 | 2016-10-27 | 公開日 | 2017-11-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Structural basis of pyrrole polymerization in human porphobilinogen deaminase. Biochim Biophys Acta Gen Subj, 1862, 2018
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7AV8
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![BU of 7av8 by Molmil](/molmil-images/mine/7av8) | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P21212 | 分子名称: | PH-interacting protein | 著者 | Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC) | 登録日 | 2020-11-04 | 公開日 | 2021-01-13 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P21212 To Be Published
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6SIQ
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![BU of 6siq by Molmil](/molmil-images/mine/6siq) | Fragment AZ-012 binding at the p53pT387/14-3-3 sigma interface | 分子名称: | 14-3-3 protein sigma, 4-chloranyl-7-propan-2-yloxy-1-benzothiophene-2-carboximidamide, CHLORIDE ION, ... | 著者 | Leysen, S, Wolter, M, Guillory, X, Genet, S, Somsen, B, Patel, J, Castaldi, P, Ottmann, C. | 登録日 | 2019-08-10 | 公開日 | 2020-06-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.60121 Å) | 主引用文献 | Fragment-based Differential Targeting of PPI Stabilizer Interfaces. J.Med.Chem., 63, 2020
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7AWD
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![BU of 7awd by Molmil](/molmil-images/mine/7awd) | Crystal structure of Peroxisome proliferator-activated receptor gamma (PPARG)in complex with garcinoic acid | 分子名称: | (2Z,6E,10E)-13-[(2R)-6-hydroxy-2,8-dimethyl-3,4-dihydro-2H-1-benzopyran-2-yl]-2,6,10-trimethyltrideca-2,6,10-trienoic acid, CITRIC ACID, GLYCEROL, ... | 著者 | Chaikuad, A, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2020-11-06 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Endogenous vitamin E metabolites mediate allosteric PPAR gamma activation with unprecedented co-regulatory interactions. Cell Chem Biol, 28, 2021
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5M9V
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![BU of 5m9v by Molmil](/molmil-images/mine/5m9v) | Human angiogenin PD/ALS variant R121C | 分子名称: | Angiogenin, GLUTATHIONE, L(+)-TARTARIC ACID | 著者 | Bradshaw, W.J, Rehman, S, Pham, T.T.K, Thiyagarajan, N, Lee, R.L, Subramanian, V, Acharya, K.R. | 登録日 | 2016-11-02 | 公開日 | 2017-02-22 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Sci Rep, 7, 2017
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7B7N
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![BU of 7b7n by Molmil](/molmil-images/mine/7b7n) | Human herpesvirus-8 gH/gL in complex with EphA2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Pederzoli, R, Guardado-Calvo, P, Rey, F.A, Backovic, M. | 登録日 | 2020-12-11 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling. Plos Biol., 19, 2021
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5MBT
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![BU of 5mbt by Molmil](/molmil-images/mine/5mbt) | CeuE (H227L, Y288F variant) a periplasmic protein from Campylobacter jejuni | 分子名称: | Enterochelin uptake periplasmic binding protein | 著者 | Wilde, E.J, Blagova, E.V, Hughes, A, Raines, D.J, Moroz, O.V, Turkenburg, J.P, Duhme-Klair, A.-K, Wilson, K.S. | 登録日 | 2016-11-08 | 公開日 | 2017-04-12 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length. Sci Rep, 7, 2017
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6SRA
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![BU of 6sra by Molmil](/molmil-images/mine/6sra) | Crystal structure of glutathione transferase Omega 2C from Trametes versicolor in complex with naringenin | 分子名称: | GLUTATHIONE, R-naringenin, glutathione transferase | 著者 | Schwartz, M, Favier, F, Didierjean, C. | 登録日 | 2019-09-05 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.206 Å) | 主引用文献 | Diversity of Omega Glutathione Transferases in mushroom-forming fungi revealed by phylogenetic, transcriptomic, biochemical and structural approaches. Fungal Genet Biol., 148, 2021
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5MC9
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6SQB
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![BU of 6sqb by Molmil](/molmil-images/mine/6sqb) | Crystal structure of M. tuberculosis InhA in complex with NAD+ and 3-(3-chlorophenyl)propanoic acid | 分子名称: | 3-(3-chlorophenyl)propanoic acid, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Enoyl-[acyl-carrier-protein] reductase [NADH], ... | 著者 | Mendes, V, Sabbah, M, Coyne, A.G, Abell, C, Blundell, T.L. | 登録日 | 2019-09-03 | 公開日 | 2020-04-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.774 Å) | 主引用文献 | Fragment-Based Design ofMycobacterium tuberculosisInhA Inhibitors. J.Med.Chem., 63, 2020
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5MCN
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![BU of 5mcn by Molmil](/molmil-images/mine/5mcn) | Radiation damage to GH7 Family Cellobiohydrolase from Daphnia pulex: Dose (DWD) 22.7 MGy | 分子名称: | Cellobiohydrolase CHBI, GLYCEROL, SULFATE ION | 著者 | Bury, C.S, McGeehan, J.E, Ebrahim, A, Garman, E.F. | 登録日 | 2016-11-10 | 公開日 | 2017-01-11 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | OH cleavage from tyrosine: debunking a myth. J Synchrotron Radiat, 24, 2017
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6SQD
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![BU of 6sqd by Molmil](/molmil-images/mine/6sqd) | Crystal structure of M. tuberculosis InhA in complex with NAD+ and 2-pyrazol-1-ylbenzoic acid | 分子名称: | 2-pyrazol-1-ylbenzoic acid, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Mendes, V, Sabbah, M, Coyne, A.G, Abell, C, Blundell, T.L. | 登録日 | 2019-09-03 | 公開日 | 2020-04-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Fragment-Based Design ofMycobacterium tuberculosisInhA Inhibitors. J.Med.Chem., 63, 2020
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5MDQ
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6SQS
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![BU of 6sqs by Molmil](/molmil-images/mine/6sqs) | Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub | 分子名称: | E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ... | 著者 | Magnussen, H.M, Ahmed, S.F, Huang, D.T. | 登録日 | 2019-09-04 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain. Nat Commun, 11, 2020
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5ME9
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![BU of 5me9 by Molmil](/molmil-images/mine/5me9) | Crystal structure of yeast Cdt1 (N terminal and middle domain), form 1. | 分子名称: | Cell division cycle protein CDT1, GLYCEROL, SULFATE ION | 著者 | Pye, V.E, Frigola, J, Diffley, J.F.X, Cherepanov, P. | 登録日 | 2016-11-14 | 公開日 | 2017-05-17 | 最終更新日 | 2017-07-05 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Cdt1 stabilizes an open MCM ring for helicase loading. Nat Commun, 8, 2017
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6ST4
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