5M7F
Human porphobilinogen deaminase in complex with DPM cofactor
Summary for 5M7F
Entry DOI | 10.2210/pdb5m7f/pdb |
Descriptor | Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | porphobilinogen deaminase, heme biosynthesis, porphyria, hmbs, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 81987.29 |
Authors | Pluta, P.,Millet, O.,Roversi, P.,Rojas, A.L.,Gu, S. (deposition date: 2016-10-27, release date: 2017-11-15, Last modification date: 2024-01-17) |
Primary citation | Pluta, P.,Roversi, P.,Bernardo-Seisdedos, G.,Rojas, A.L.,Cooper, J.B.,Gu, S.,Pickersgill, R.W.,Millet, O. Structural basis of pyrrole polymerization in human porphobilinogen deaminase. Biochim Biophys Acta Gen Subj, 1862:1948-1955, 2018 Cited by PubMed: 29908816DOI: 10.1016/j.bbagen.2018.06.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.78 Å) |
Structure validation
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