PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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4R7E	Structure of Bre1 RING domain 分子名称: E3 ubiquitin-protein ligase BRE1, ZINC ION 著者 Kumar, P, Wolberger, C. 登録日 2014-08-27 公開日 2015-05-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.251 Å) 主引用文献 Structure of the yeast Bre1 RING domain. Proteins, 83, 2015
7TDV	Crystal structure of S. aureus glutamine synthetase in Met-Sox-P/ADP transition state complex 分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ... 著者 Schumacher, M.A. 登録日 2022-01-03 公開日 2022-06-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
5A50	The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions, Zn and Phopho Choline 分子名称: AT3G17980, CALCIUM ION, PHOSPHOCHOLINE, ... 著者 Diaz, M, Albert, A. 登録日 2015-06-16 公開日 2016-03-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling. Proc.Natl.Acad.Sci.USA, 113, 2016
4GU1	Crystal structure of LSD2 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... 著者 Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. 登録日 2012-08-29 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.939 Å) 主引用文献 LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
4GUU	Crystal structure of LSD2-NPAC with tranylcypromine 分子名称: Lysine-specific histone demethylase 1B, Putative oxidoreductase GLYR1, ZINC ION, ... 著者 Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Xu, Y. 登録日 2012-08-29 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
5A6H	Synthesis, carbonic anhydrase inhibition and protein X-ray structure of the unusual natural product primary sulfonamide Psammaplin C 分子名称: CARBONIC ANHYDRASE 2, DIMETHYL SULFOXIDE, PSAMMAPLIN C, ... 著者 Mujumdar, P, Supuran, C.T, Peat, T.S, Poulsen, S. 登録日 2015-06-26 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition and Protein X-Ray Structures of Psammaplin C. J.Med.Chem., 59, 2016
6CQA	E. coli DHFR complex with inhibitor AMPQD 分子名称: 7-[(3-aminophenyl)methyl]-7H-pyrrolo[3,2-f]quinazoline-1,3-diamine, Dihydrofolate reductase, SULFATE ION 著者 Cao, H, Rodrigues, J, Benach, J, Wasserman, S, Morisco, L, Koss, J, Shakhnovich, E, Skolnick, J. 登録日 2018-03-14 公開日 2019-01-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The crystal structure of a tetrahydrofolate-bound dihydrofolate reductase reveals the origin of slow product release. Commun Biol, 1, 2018
6CR5	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with CH2-beta, gamma dATP analogue 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonomethyl)phosphoryl]oxy}phosphoryl]adenosine, DNA polymerase beta, Downstream Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-03-16 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.982 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
6CRH	Structure of human DNA polymerase beta complexed with 8-ClG in the template base paired with incoming non-hydrolyzable GTP 分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*CP*CP*GP*AP*CP*(CGM)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2018-03-17 公開日 2019-03-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.327 Å) 主引用文献 Promutagenicity of 8-Chloroguanine, A Major Inflammation-Induced Halogenated DNA Lesion. Molecules, 24, 2019
6UYH	Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP 分子名称: 1,2-ETHANEDIOL, 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-11-13 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of prolyl-tRNA synthetase from Naegleria fowleri in complex with halofuginone and AMPPNP TO BE PUBLISHED
8KG8	Yeast replisome in state II 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
6VDV	Crystal Structure of Dehaloperoxidase B in Complex with cofactor Manganese(III)- Porphyrin and Substrate 4-bromophenol 分子名称: 1,2-ETHANEDIOL, 4-BROMOPHENOL, Dehaloperoxidase B, ... 著者 Ghiladi, R.A, de Serrano, V.S, McGuire, A, Malewschik, T. 登録日 2019-12-27 公開日 2020-12-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Nonnative Heme Incorporation into Multifunctional Globin Increases Peroxygenase Activity an Order and Magnitude Compared to Native Enzyme To Be Published
7TEN	Crystal structure of the Listeria monocytogenes GS-Met-Sox-P- ADP complex to 3.5 Angstrom 分子名称: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE 著者 Schumacher, M.A. 登録日 2022-01-05 公開日 2022-06-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
6CS0	SARS Spike Glycoprotein, Trypsin-cleaved, Stabilized variant, one S1 CTD in an upwards conformation 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,Fibritin, ... 著者 Kirchdoerfer, R.N, Wang, N, Pallesen, J, Turner, H.L, Cottrell, C.A, McLellan, J.S, Ward, A.B. 登録日 2018-03-19 公開日 2018-04-11 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis. Sci Rep, 8, 2018
5A3B	Crystal structure of the ADP-ribosylating sirtuin (SirTM) from Streptococcus pyogenes in complex with ADP-ribose 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, ALANINE, ... 著者 Rack, J.G.M, Morra, R, Barkauskaite, E, Kraehenbuehl, R, Ariza, A, Qu, Y, Ortmayer, M, Leidecker, O, Cameron, D.R, Matic, I, Peleg, A.Y, Leys, D, Traven, A, Ahel, I. 登録日 2015-05-28 公開日 2015-07-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Identification of a Class of Protein Adp-Ribosylating Sirtuins in Microbial Pathogens. Mol.Cell, 59, 2015
4RAY	Crystal structure of Magnetospirillum gryphiswaldense MSR-1 Apo-Fur 分子名称: CITRATE ANION, DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport(Fur family), SULFATE ION 著者 Deng, Z, Liu, Z, Chen, Z. 登録日 2014-09-12 公開日 2015-07-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator. Nat Commun, 6
6CTQ	Ternary complex crystal structure of DNA polymerase Beta with a dideoxy terminated primer with dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2018-03-23 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
7QLM	rsKiiro trans chromophore dark structure by SFX 分子名称: rsKiiro 著者 van Thor, J.J. 登録日 2021-12-20 公開日 2023-09-27 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Optical control of ultrafast structural dynamics in a fluorescent protein. Nat.Chem., 15, 2023
8KG6	Yeast replisome in state I 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, Chromosome segregation in meiosis protein 3, ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.07 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
8KG9	Yeast replisome in state III 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cell division control protein 45, DNA (61-mer), ... 著者 Dang, S, Zhai, Y, Feng, J, Yu, D, Xu, Z. 登録日 2023-08-17 公開日 2023-12-06 実験手法 ELECTRON MICROSCOPY (4.52 Å) 主引用文献 Synergism between CMG helicase and leading strand DNA polymerase at replication fork. Nat Commun, 14, 2023
4R62	Structure of Rad6~Ub 分子名称: ACETATE ION, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 2 著者 Kumar, P, Wolberger, C. 登録日 2014-08-22 公開日 2015-09-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity. Nucleic Acids Res., 43, 2015
7QLN	rsKiiro pump probe structure by TR-SFX 分子名称: rsKiiro 著者 van Thor, J.J. 登録日 2021-12-20 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Optical control of ultrafast structural dynamics in a fluorescent protein. Nat.Chem., 15, 2023
6CUT	Engineered Holo TrpB from Pyrococcus furiosus, PfTrpB7E6 with (2S,3S)-isopropylserine bound as the external aldimine 分子名称: (2S,3S)-3-hydroxy-2-[(E)-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)amino]-4-methylpentanoic acid (non-preferred name), SODIUM ION, Tryptophan synthase beta chain 1 著者 Boville, C.E, Scheele, R.A, Buller, A.R, Arnold, F.H. 登録日 2018-03-26 公開日 2018-09-26 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Engineered Biosynthesis of beta-Alkyl Tryptophan Analogues. Angew. Chem. Int. Ed. Engl., 57, 2018
4QTB	Structure of human ERK1 in complex with SCH772984 revealing a novel inhibitor-induced binding pocket 分子名称: (3R)-1-(2-oxo-2-{4-[4-(pyrimidin-2-yl)phenyl]piperazin-1-yl}ethyl)-N-[3-(pyridin-4-yl)-2H-indazol-5-yl]pyrrolidine-3-carboxamide, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Chaikuad, A, Keates, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2014-07-07 公開日 2014-07-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A unique inhibitor binding site in ERK1/2 is associated with slow binding kinetics. Nat.Chem.Biol., 10, 2014
7TTJ	Stable-5-LOX elongated Ha2 分子名称: Arachidonate 5-lipoxygenase, FE (II) ION 著者 Gilbert, N.C, Newcomer, M.E. 登録日 2022-02-01 公開日 2022-08-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Helical remodeling augments 5-lipoxygenase activity in the synthesis of proinflammatory mediators. J.Biol.Chem., 298, 2022

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